| Metabolic reprogramming commits differentiation of human CD27+ IgD+ B cells to plasmablasts or CD27− IgD− cells M Torigoe, S Iwata, S Nakayamada, K Sakata, M Zhang, M Hajime, ... The Journal of Immunology 199 (2), 425-434, 2017 | 89 | 2017 |
| Expansion of T follicular helper-T helper 1 like cells through epigenetic regulation by signal transducer and activator of transcription factors X Ma, S Nakayamada, S Kubo, K Sakata, K Yamagata, Y Miyazaki, ... Annals of the Rheumatic Diseases 77 (9), 1354-1361, 2018 | 69 | 2018 |
| conversion of T follicular helper cells to T follicular regulatory cells by interleukin‐2 through transcriptional regulation in systemic lupus Erythematosus H Hao, S Nakayamada, K Yamagata, N Ohkubo, S Iwata, Y Inoue, ... Arthritis & Rheumatology 73 (1), 132-142, 2021 | 55 | 2021 |
| Relevance of interferon-gamma in pathogenesis of life-threatening rapidly progressive interstitial lung disease in patients with dermatomyositis Y Ishikawa, S Iwata, K Hanami, A Nawata, M Zhang, K Yamagata, ... Arthritis Research & Therapy 20, 1-10, 2018 | 49 | 2018 |
| Methionine commits cells to differentiate into plasmablasts through epigenetic regulation of BTB and CNC homolog 2 by the methyltransferase EZH 2 M Zhang, S Iwata, M Hajime, N Ohkubo, Y Todoroki, H Miyata, M Ueno, ... Arthritis & Rheumatology 72 (7), 1143-1153, 2020 | 32 | 2020 |
| An enhanced mitochondrial function through glutamine metabolism in plasmablast differentiation in systemic lupus erythematosus MH Sumikawa, S Iwata, M Zhang, H Miyata, M Ueno, Y Todoroki, ... Rheumatology 61 (7), 3049-3059, 2022 | 23 | 2022 |
| Involvement of lncRNA IL21-AS1 in interleukin-2 and T follicular regulatory cell activation in systemic lupus erythematosus H Hao, S Nakayamada, N Ohkubo, K Yamagata, M Zhang, Y Shan, ... Arthritis Research & Therapy 23 (1), 302, 2021 | 17 | 2021 |
| Enhanced fatty acid synthesis leads to subset imbalance and IFN-γ overproduction in T helper 1 cells S Iwata, M Zhang, H Hao, G Trimova, M Hajime, Y Miyazaki, N Ohkubo, ... Frontiers in Immunology 11, 593103, 2020 | 17 | 2020 |
| Modulation of the itaconate pathway attenuates murine lupus LP Blanco, E Patino‐Martinez, S Nakabo, M Zhang, HL Pedersen, ... Arthritis & Rheumatology 74 (12), 1971-1983, 2022 | 10 | 2022 |
| Simultaneous occurrence of Hodgkin's lymphoma and multiple myeloma: a case report and review of the literature C Huang, G Zhao, L Wang, H Zhang, X Wu, M Zhang, R Ma, L Wang, ... Oncology Letters 11 (6), 4139-4143, 2016 | 10 | 2016 |
| Pathological role of activated mTOR in CXCR3+ memory B cells of rheumatoid arthritis S Iwata, M Zhang, M Hajime, N Ohkubo, K Sonomoto, K Torimoto, ... Rheumatology 60 (11), 5452-5462, 2021 | 9 | 2021 |
| mTOR activation in CD8+ cells contributes to disease activity of rheumatoid arthritis and increases therapeutic response to TNF inhibitors M Zhang, S Iwata, K Sonomoto, M Ueno, Y Fujita, J Anan, Y Miyazaki, ... Rheumatology 61 (7), 3010-3022, 2022 | 6 | 2022 |
| Enhanced Fatty Acid Synthesis Leads to Subset Imbalance and IFN-g Overproduction in T Helper 1 Cells S Iwata, M Zhang, H Hao, G Trimova, M Hajime, Y Miyazaki, N Ohkubo, ... Focusing on T-cells for Novel Treatments of Systemic Lupus Erythematosus, 2021 | | 2021 |
| Methionine Commits Immunometabolism and Epigenetic Regulation of BACH2 Loci in B Cells, Resulting in Biases Toward Plasmablast Differentiation in the Pathogenesis of SLE M Zhang, S Iwata, M Hajime, N Ohkubo, Y Todoroki, H Miyata, J Fan, ... ARTHRITIS & RHEUMATOLOGY 71, 2019 | | 2019 |
| mTORC1-phosphorylated CXCR3+memory B Cells and Their Potential as a New Mode of Action of TNF Inhibitors in RA S Iwata, M Zhang, M Hajime, N Ohkubo, Y Kitanaga, G Trimova, ... ARTHRITIS & RHEUMATOLOGY 71, 2019 | | 2019 |
| 1731-P: The Involvement of Glutaminolysis in ß-Cell Differentiation and Its Clinical Application for Type 1 Diabetes M Hajime, S Iwata, M Zhang, S Nakayamada, Y Okada, Y Tanaka Diabetes 68 (Supplement_1), 2019 | | 2019 |
| OP0196 IMBALANCE BETWEEN MEMORY TH1 AND TH1-TREG CELLS DEPENDS ON DIFFERENTIAL REGULATION OF CELL METABOLISM IN PATIENTS WITH SLE S Iwata, M Zhang, M Hajime, N Ohkubo, H Miyata, Y Todoroki, ... Annals of the Rheumatic Diseases 78 (Suppl 2), 173-174, 2019 | | 2019 |
| THU0243 ROLE OF METHIONINE AND ITS TRANSPORTER CD98 IN HUMAN B CELL DIFFERENTIATION AND THE RELEVANCE TO PATHOLOGICAL PROCESSES OF SLE M Zhang, S Iwata, M Hajime, N Ohkubo, Y Todoroki, H Miyata, ... Annals of the Rheumatic Diseases 78 (Suppl 2), 398-399, 2019 | | 2019 |
| THU0219 THE INVOLVEMENT OF MITOCHONDRIAL ACTIVATION VIA GLUTAMINOLYSIS IN HUMAN B CELL DIFFERENTIATION AND ITS RELEVANCE TO THE PATHOGENESIS OF SLE M Hajime, S Iwata, M Zhang, H Miyata, S Lee, S Nakayamada, ... Annals of the Rheumatic Diseases 78 (Suppl 2), 388-388, 2019 | | 2019 |
| 30 Metabolic reprogramming in cd4+ cd28-cxcr3intt-bethi cells and its relevance to pathogenesis in patients with sle S Iwata, K Sakata, M Hajime, M Zhang, M Torigoe, N Ohkubo, ... Lupus Science & Medicine 4 (Suppl 1), 2017 | | 2017 |
