mRNA vaccine–induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer G Cafri, JJ Gartner, T Zaks, K Hopson, N Levin, BC Paria, MR Parkhurst, ... The Journal of clinical investigation 130 (11), 5976-5988, 2020 | 272 | 2020 |
Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers FJ Lowery, S Krishna, R Yossef, NB Parikh, PD Chatani, N Zacharakis, ... Science 375 (6583), 877-884, 2022 | 208 | 2022 |
Adoptive cellular therapy with autologous tumor-infiltrating lymphocytes and T-cell receptor–engineered T cells targeting common p53 neoantigens in human solid tumors SP Kim, NR Vale, N Zacharakis, S Krishna, Z Yu, B Gasmi, JJ Gartner, ... Cancer immunology research 10 (8), 932-946, 2022 | 64 | 2022 |
Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy N Levin, BC Paria, NR Vale, R Yossef, FJ Lowery, MR Parkhurst, Z Yu, ... Clinical Cancer Research 27 (18), 5084-5095, 2021 | 26 | 2021 |
Rapid identification and evaluation of neoantigen-reactive T-cell receptors from single cells BC Paria, N Levin, FJ Lowery, A Pasetto, DC Deniger, MR Parkhurst, ... Journal of Immunotherapy 44 (1), 1-8, 2021 | 26 | 2021 |
Membrane-attached cytokines expressed by mRNA electroporation act as potent T-cell adjuvants H Weinstein-Marom, A Pato, N Levin, K Susid, O Itzhaki, MJ Besser, ... Journal of immunotherapy 39 (2), 60-70, 2016 | 24 | 2016 |
Spontaneous activation of antigen-presenting cells by genes encoding truncated homo-oligomerizing derivatives of CD40 N Levin, A Pato, G Cafri, G Eisenberg, T Peretz, A Margalit, M Lotem, ... Journal of Immunotherapy 40 (2), 39-50, 2017 | 15 | 2017 |
Potent activation of human T cells by mRNA encoding constitutively active CD40 N Levin, H Weinstein-Marom, A Pato, O Itzhaki, MJ Besser, G Eisenberg, ... The Journal of Immunology 201 (10), 2959-2968, 2018 | 14 | 2018 |
Combined expression of genetic adjuvants via mRNA electroporation exerts multiple immunostimulatory effects on antitumor T cells H Weinstein-Marom, N Levin, A Pato, N Shmuel, A Sharabi-Nov, T Peretz, ... Journal of Immunotherapy 42 (2), 43-50, 2019 | 8 | 2019 |
Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers R Yossef, S Krishna, S Sindiri, FJ Lowery, AR Copeland, JJ Gartner, ... Cancer Cell 41 (12), 2154-2165. e5, 2023 | 5 | 2023 |
The intracellular domain of CD40 is a potent costimulatory element in chimeric antigen receptors O Levin-Piaeda, N Levin, S Pozner, A Danieli, H Weinstein-Marom, ... Journal of Immunotherapy 44 (6), 209-213, 2021 | 5 | 2021 |
Single cell mapping of tumor infiltrating lymphocytes enables neoantigen-reactive T cell identification in metastatic human cancer FJ Lowery, S Krishna, R Yossef, PD Chatani, NB Parikh, YC Lu, ... Cancer Research 81 (13_Supplement), 127-127, 2021 | 2 | 2021 |
Identification of T-cell receptors targeting RAS hotspot mutations using TIL IVS in human cancers for use in cell-based immunotherapy N Levin, FJ Lowery, MR Parkhurst, Z Yu, NR Vale, SP Kim, SA Rosenberg Cancer Research 82 (12_Supplement), 3576-3576, 2022 | 1 | 2022 |
Adoptive transfer of T lymphocytes retrovirally transduced to express personalized neoantigen reactive T cell receptors can mediate tumor regression in patients with metastatic … M Parkhurst, S Goff, F Lowery, R Beyer, H Halas, P Robbins, J Gartner, ... | | 2024 |
Adoptive Transfer of T Cells Genetically Engineered to Express T-Cell Receptors Targeting Neoantigens Arising from p53 and Ras Hotspot Mutations in Hematologic Malignancies KM Cappell, SP Kim, N Levin, N Lam, C Amatya, LC Cutmore, R Beyer, ... Blood 142, 888, 2023 | | 2023 |
Hla class ii-restricted dq t cell receptors against ras with g13d mutation N Levin, FJ Lowery III, BC Paria, SA Rosenberg, R Yoseph US Patent App. 18/027,981, 2023 | | 2023 |
366 Neoantigen-specific stimulation of T cells for effective cancer adoptive cell therapies S Kim, N Levin, C Marquardt, SA Rosenberg Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
1216 Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers S Krishna, R Yoseph, S Sindiri, F Lowery, N Parikh, N Zacharakis, N Levin, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
Hla class ii-restricted drb t cell receptors against ras with g12d mutation N Levin, R Yoseph, G Cafri, SA Rosenberg US Patent App. 18/015,776, 2023 | | 2023 |
Hla class ii-restricted drb t cell receptors against ras with g12v mutation N Levin, FJ Lowery III, MR Parkhurst, SA Rosenberg US Patent App. 18/015,781, 2023 | | 2023 |