Leveraging polygenic functional enrichment to improve GWAS power G Kichaev, G Bhatia, PR Loh, S Gazal, K Burch, MK Freund, A Schoech, ... The American Journal of Human Genetics 104 (1), 65-75, 2019 | 803 | 2019 |
Mixed-model association for biobank-scale datasets PR Loh, G Kichaev, S Gazal, AP Schoech, AL Price Nature genetics 50 (7), 906-908, 2018 | 598 | 2018 |
Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection S Gazal, HK Finucane, NA Furlotte, PR Loh, PF Palamara, X Liu, ... Nature genetics 49 (10), 1421-1427, 2017 | 415 | 2017 |
Functionally informed fine-mapping and polygenic localization of complex trait heritability O Weissbrod, F Hormozdiari, C Benner, R Cui, J Ulirsch, S Gazal, ... Nature genetics 52 (12), 1355-1363, 2020 | 208 | 2020 |
Extreme polygenicity of complex traits is explained by negative selection LJ O'Connor, AP Schoech, F Hormozdiari, S Gazal, N Patterson, AL Price The American Journal of Human Genetics 105 (3), 456-476, 2019 | 203 | 2019 |
Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits F Hormozdiari, S Gazal, B Van De Geijn, HK Finucane, CJT Ju, PR Loh, ... Nature genetics 50 (7), 1041-1047, 2018 | 156 | 2018 |
Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations S Gazal, PR Loh, HK Finucane, A Ganna, A Schoech, S Sunyaev, ... Nature genetics 50 (11), 1600-1607, 2018 | 142 | 2018 |
Population-specific causal disease effect sizes in functionally important regions impacted by selection H Shi, S Gazal, M Kanai, EM Koch, AP Schoech, KM Siewert, SS Kim, ... Nature communications 12 (1), 1098, 2021 | 129 | 2021 |
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection AP Schoech, DM Jordan, PR Loh, S Gazal, LJ O’Connor, DJ Balick, ... Nature communications 10 (1), 790, 2019 | 104 | 2019 |
The evolution of quorum sensing as a mechanism to infer kinship J Schluter, AP Schoech, KR Foster, S Mitri PLoS computational biology 12 (4), e1004848, 2016 | 74 | 2016 |
Quantification of frequency-dependent genetic architectures and action of negative selection in 25 UK Biobank traits AP Schoech, D Jordan, PR Loh, S Gazal, L O’Connor, DJ Balick, ... BioRxiv, 188086, 2017 | 22 | 2017 |
Facilitated diffusion buffers noise in gene expression AP Schoech, NR Zabet Physical Review E 90 (3), 032701, 2014 | 8 | 2014 |
Quantification of genetic components of population differentiation in UK Biobank traits reveals signals of polygenic selection X Liu, PR Loh, LJ O’Connor, S Gazal, A Schoech, RM Maier, N Patterson, ... Biorxiv, 357483, 2018 | 7 | 2018 |
Leveraging molecular QTL to understand the genetic architecture of diseases and complex traits F Hormozdiari, S Gazal, B Geijn, H Finucane, CJT Ju, PR Loh, A Schoech, ... bioRxiv, 203380, 2017 | 6 | 2017 |
Quantification of frequency-dependent genetic architectures and action of negative selection in 25 UK Biobank traits. bioRxiv A Schoech, D Jordan, PR Loh, S Gazal, L O’Connor, DJ Balick, ... September, 2017 | 6 | 2017 |
Mixed model association for biobank-scale data sets. bioRxiv PR Loh, G Kichaev, S Gazal, AP Schoech, AL Price DOI: https://doi org/101101/194944, 2017 | 6 | 2017 |
Negative short-range genomic autocorrelation of causal effects on human complex traits AP Schoech, O Weissbrod, LJ O’Connor, N Patterson, H Shi, Y Reshef, ... bioRxiv, 2020.09. 23.310748, 2020 | 5 | 2020 |
Low-frequency variant functional architectures reveal strength of negative selection across coding and non-coding annotations S Gazal, PR Loh, HK Finucane, A Ganna, A Schoech, S Sunyaev, ... bioRxiv, 297572, 2018 | 3 | 2018 |
Author Correction: Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection. S Gazal, HK Finucane, NA Furlotte, PR Loh, PF Palamara, X Liu, ... Nature Genetics 51 (8), 1295-1295, 2019 | 1 | 2019 |
Statistical Inference of Signatures of Natural Selection in Human Complex Trait Genetic Architecture AP Schoech Harvard University, 2020 | | 2020 |