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Rasmus O. Bak
Rasmus O. Bak
Associate Professor, PhD, Aarhus University, Dept. of Biomedicine
Verified email at biomed.au.dk - Homepage
Title
Cited by
Cited by
Year
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
A Hendel*, RO Bak*, JT Clark, AB Kennedy, DE Ryan, S Roy, I Steinfeld, ...
Nature Biotechnology, 2015
11562015
Activation of proto-oncogenes by disruption of chromosome neighborhoods
D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ...
Science, 2016
10232016
CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
DP Dever*, RO Bak*, A Reinisch, J Camarena, G Washington, CE Nicolas, ...
Nature, 2016
8872016
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells
CA Vakulskas, DP Dever, GR Rettig, R Turk, AM Jacobi, MA Collingwood, ...
Nature medicine 24 (8), 1216-1224, 2018
7082018
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
MR Jakobsen, RO Bak, A Andersen, RK Berg, SB Jensen, T Jin, ...
PNAS, 2013
3732013
CRISPR/Cas9 genome editing in human hematopoietic stem cells
RO Bak, DP Dever, MH Porteus
Nature protocols 13 (2), 358-376, 2018
2802018
Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses
CK Holm, SH Rahbek, HH Gad, RO Bak, MR Jakobsen, Z Jiang, ...
Nature Communications, 2016
2112016
miRNA sponges: soaking up miRNAs for regulation of gene expression
RO Bak, JG Mikkelsen
Wiley Interdisciplinary Reviews (WIREs): RNA, 2014
2032014
Gene editing on center stage
RO Bak, N Gomez-Ospina, MH Porteus
Trends in Genetics 34 (8), 600-611, 2018
1652018
Highly efficient and marker-free genome editing of human pluripotent stem cells by CRISPR-Cas9 RNP and AAV6 donor-mediated homologous recombination
RM Martin, K Ikeda, MK Cromer, N Uchida, T Nishimura, R Romano, ...
Cell stem cell 24 (5), 821-828. e5, 2019
1622019
Regulation of pro-inflammatory cytokines TNFα and IL24 by microRNA-203 in primary keratinocytes
MN Primo, RO Bak, B Schibler, JG Mikkelsen
Cytokine, 2012
1262012
CRISPR-mediated integration of large gene cassettes using AAV donor vectors
RO Bak, MH Porteus
Cell Reports, 2017
1222017
Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6
RO Bak, DP Dever, A Reinisch, DC Hernandez, R Majeti, MH Porteus
eLife, 2017
1162017
Global transcriptional response to CRISPR/Cas9-AAV6-based genome editing in CD34+ hematopoietic stem and progenitor cells
MK Cromer, S Vaidyanathan, DE Ryan, B Curry, AB Lucas, J Camarena, ...
Molecular Therapy 26 (10), 2431-2442, 2018
1092018
Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases
Y Cai, RO Bak, JG Mikkelsen
eLife, 2014
1092014
Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I
N Gomez-Ospina, SG Scharenberg, N Mostrel, RO Bak, S Mantri, ...
Nature Communications 10, 4045, 2019
1042019
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease
A Lattanzi, J Camarena, P Lahiri, H Segal, W Srifa, CA Vakulskas, ...
Science translational medicine 13 (598), eabf2444, 2021
972021
Potent microRNA suppression by RNA Pol II-transcribed ‘Tough Decoy’inhibitors
RO Bak, AK Hollensen, MN Primo, CD Sørensen, JG Mikkelsen
RNA, 2013
892013
Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells
B Moldt, C Miskey, NH Staunstrup, A Gogol-Döring, RO Bak, N Sharma, ...
Molecular Therapy, 2011
892011
STEEP mediates STING ER exit and activation of signaling
B Zhang, R Nandakumar, LS Reinert, J Huang, A Laustsen, Z Gao, C Sun, ...
Nature immunology 21 (8), 868-879, 2020
862020
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