PPARα-UGT axis activation represses intestinal FXR-FGF15 feedback signalling and exacerbates experimental colitis X Zhou, L Cao, C Jiang, Y Xie, X Cheng, KW Krausz, Y Qi, L Sun, ... Nature communications 5 (1), 4573, 2014 | 154 | 2014 |
Ginsenosides regulate PXR/NF-κB signaling and attenuate dextran sulfate sodium–induced colitis J Zhang, L Cao, H Wang, X Cheng, L Wang, L Zhu, T Yan, Y Xie, Y Wu, ... Drug Metabolism and Disposition 43 (8), 1181-1189, 2015 | 55 | 2015 |
Altenusin, a nonsteroidal microbial metabolite, attenuates nonalcoholic fatty liver disease by activating the farnesoid X receptor Z Zheng, Z Zhao, S Li, X Lu, M Jiang, J Lin, Y An, Y Xie, M Xu, W Shen, ... Molecular pharmacology 92 (4), 425-436, 2017 | 38 | 2017 |
Intestinal Sulfation is Essential to Protect Against Colitis and Colonic Carcinogenesis WX Pengfei Xu, Yue Xi, Junjie Zhu, Min Zhang, Zigmund Luka, Donna B. Stolz ... Gastroenterology, 2021 | 35 | 2021 |
The Role of Sulfotransferases in Liver Diseases WX Yang Xie Drug Metabolism and Disposition 48 (7), 2020 | 33 | 2020 |
Farnesoid X receptor activation promotes cell proliferation via PDK4-controlled metabolic reprogramming Y Xie, H Wang, X Cheng, Y Wu, L Cao, M Wu, W Xie, G Wang, H Hao Scientific Reports 6 (1), 18751, 2016 | 32 | 2016 |
Disturbance of hepatic and intestinal UDP-glucuronosyltransferase in rats with trinitrobenzene sulfonic acid-induced colitis X Zhou, Y Xie, Q Qi, X Cheng, F Liu, K Liao, G Wang, H Hao Drug metabolism and pharmacokinetics 28 (4), 305-313, 2013 | 23 | 2013 |
Activation of Pregnane X Receptor Sensitizes Mice to Hemorrhagic Shock Induced Liver Injury. Y Xie, M Xu, M Deng, Z Li, P Wang, S Ren, Y Guo, X Ma, J Fan, T Billiar, ... Hepatology, 2019 | 22 | 2019 |
Mechanism-Based Inhibitory and Peroxisome Proliferator-Activated Receptor α–Dependent Modulating Effects of Silybin on Principal Hepatic Drug-Metabolizing Enzymes H Wang, T Yan, Y Xie, M Zhao, Y Che, J Zhang, H Liu, L Cao, X Cheng, ... Drug Metabolism and Disposition 43 (4), 444-454, 2015 | 21 | 2015 |
DNA binding by the MATα2 transcription factor controls its access to alternative ubiquitin-modification pathways CM Hickey, Y Xie, M Hochstrasser Molecular Biology of the Cell 29 (5), 542-556, 2018 | 18 | 2018 |
Regulation of drug-metabolizing enzymes by local and systemic liver injuries Y Guo, B Hu, Y Xie, TR Billiar, JL Sperry, M Huang, W Xie Expert opinion on drug metabolism & toxicology 12 (3), 245-251, 2016 | 17 | 2016 |
Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice YLWX Anne C. Silva Barbosa, Dong Zhou, Yang Xie, You-Jin Choi, Hung-Chun ... JASN 31 (6), 2020 | 14* | 2020 |
Molecular genetics of the ubiquitin-proteasome system: lessons from yeast M Hochstrasser, M Deng, AR Kusmierczyk, X Li, SG Kreft, T Ravid, ... The Ubiquitin System in Health and Disease, 41-66, 2009 | 10 | 2009 |
An unexpected role of cholesterol sulfotransferase and its regulation in sensitizing mice to acetaminophen induced liver injury. Y An, P Wang, P Xu, HC Tung, Y Xie, L Kirisci, M Xu, S Ren, X Tian, X Ma, ... Mol Pharmacol., 2019 | 9 | 2019 |
Hepatic Estrogen Sulfotransferase Distantly Sensitizes Mice to Hemorrhagic Shock-Induced Acute Lung Injury WX Yang Xie, Anne Caroline S Barbosa, Meishu Xu, Patrick J Oberly, Songrong ... Endocrinology, 2019 | 7* | 2019 |
Chronic Activation of LXRα Sensitizes Mice to Hepatocellular Carcinoma Y Xie, R Sun, L Gao, J Guan, J Wang, A Bell, J Zhu, M Zhang, M Xu, P Lu, ... Hepatology Communications, 2022 | 6 | 2022 |
Hepatic steroid sulfatase critically determines estrogenic activities of conjugated equine estrogens in human cells in vitro and in mice Y Feng, Y Xie, M Xu, L Li, KW Selcer, PJ Oberly, SM Poloyac, H Wang, ... J Biol Chem., 2019 | 4 | 2019 |
Ligand dependent interaction between PC-TP and PPARδ mitigates diet-induced hepatic steatosis in male mice SA Druzak, M Tardelli, SG Mays, M El Bejjani, X Mo, KM Maner-Smith, ... Nature Communications 14 (1), 2748, 2023 | 2 | 2023 |
Progress in the role of farnesoid X receptor in metabolic regulation and tumor cell proliferation Y Xie, XY Zhou, HP Hao, GJ Wang Sheng li xue bao:[Acta Physiologica Sinica] 66 (2), 252-258, 2014 | 1 | 2014 |
High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease CS Krumm, RS Landzberg, L Ramos-Espiritu, C Adura, X Liu, M Acuna, ... Molecular Metabolism 78, 101832, 2023 | | 2023 |