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Guoyan Xu
Guoyan Xu
Virginia Commonwealth University, Virginia Tech
Verified email at vt.edu
Title
Cited by
Cited by
Year
Pin1 as an anticancer drug target.
GG Xu, FA Etzkorn
Drug news & perspectives 22 (7), 399-407, 2009
702009
Chemokine Receptor CCR5 Antagonist Maraviroc: Medicinal Chemistry and Clinical Applications
GG Xu, J Guo, Y Wu
Current Topics in Medicinal Chemistry 14 (13), 1504-1514, 2014
582014
Convergent synthesis of α-ketoamide inhibitors of Pin1
GG Xu, FA Etzkorn
Organic letters 12 (4), 696-699, 2010
452010
A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state
GG Xu, Y Zhang, AY Mercedes-Camacho, FA Etzkorn
Biochemistry 50 (44), 9545-9550, 2011
402011
Reaction of nitrile oxides with vinylphosphonate: A facile, regioselective approach to 5‐phosphonyl‐4, 5‐dihydroisoxazoles
Y Ye, Y Zheng, GY Xu, LZ Liu
Heteroatom Chemistry: An International Journal of Main Group Elements 14 (3 …, 2003
342003
Kinetic isotope effects support the twisted amide mechanism of Pin1 peptidyl-prolyl isomerase
AY Mercedes-Camacho, AB Mullins, MD Mason, GG Xu, BJ Mahoney, ...
Biochemistry 52 (44), 7707-7713, 2013
282013
Cyclohexyl Ketone Inhibitors of Pin1 Dock in a Trans-Diaxial Cyclohexane Conformation
GG Xu, C Slebodnick, FA Etzkorn
Public Library of Science 7 (9), e44226, 2012
192012
1, 3-dipolar cycloaddition reactions of nitrones to prop-1-ene-1, 3-sultone
L Tian, GY Xu, Y Ye, LZ Liu
Synthesis 2003 (09), 1329-1334, 2003
152003
Cycloaddition of nitrile oxides to substituted vinylphosphonates
Y Ye, GY Xu, Y Zheng, LZ Liu
Heteroatom Chemistry: An International Journal of Main Group Elements 14 (4 …, 2003
152003
1, 3‐dipolar cycloaddition reactions of nitrile oxides to prop‐1‐ene‐1, 3‐sultone
L Tian, GY Xu, Y Ye, LZ Liu
Journal of heterocyclic chemistry 40 (6), 1071-1074, 2003
142003
Exploration on natural product anibamine side chain modification toward development of novel CCR5 antagonists and potential anti-prostate cancer agents
GG Xu, SA Zaidi, F Zhang, S Singh, TJ Raborg, Y Yuan, Y Zhang
Bioorganic & medicinal chemistry letters 25 (17), 3721-3725, 2015
82015
The reaction of PhCH2C(O)NR2/P(O)Cl3 with phosphites and hydridophosphorane
WH Wang, GY Xu, RZ Cao, LZ Liu
Heteroatom Chemistry: An International Journal of Main Group Elements 11 (7 …, 2000
82000
Vzhe-039, a novel structurally-enhanced allosteric hemoglobin effector inhibits sickling of SS erythrocytes in vitro, and exhibits improved pharmacologic properties In Vivo
MK Safo, G Xu, M Ghatge, Q Chen, C Casu, D Tanya, Y Zhang, J Venitz, ...
Blood 128 (22), 3645, 2016
32016
Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease
MK Safo, Y Zhang, PP Pagare, XU Guoyan, M Ghatge, J Venitz, ...
US Patent 11,401,241, 2022
22022
Prodrug and protected forms of 5-hydroxymethylfurfuranal (5-HMF) and its derivatives
MK Safo, XU Guoyan, Y Zhang, O Abdulmalik
US Patent 10,875,834, 2020
22020
Pin1 Inhibitors: Towards Understanding the Enzymatic Mechanism
G Xu
Virginia Tech, 2010
22010
Benzaldehyde compounds with direct polymer destabilizing effects to treat sickle cell disease
M Safo, Y Zhang, PP Pagare, XU Guoyan, M Ghatge, J Venitz, ...
US Patent App. 18/501,244, 2024
2024
Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease
MK Safo, Y Zhang, PP Pagare, XU Guoyan, M Ghatge, J Venitz, ...
US Patent App. 17/846,101, 2022
2022
BIOL 57-Design and synthesis of amine and ketone inhibitors of PIN1
GG Xu, FA Etzkorn
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, 2008
2008
Synthesis of a potential transition-state analogue inhibitor for Pin1
GG Xu, FA Etzkorn
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230, U591-U592, 2005
2005
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