Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels SG Brohawn, Z Su, R MacKinnon Proceedings of the National Academy of Sciences 111 (9), 3614-3619, 2014 | 394 | 2014 |
A neural circuit for the suppression of pain by a competing need state AL Alhadeff, Z Su, E Hernandez, ML Klima, SZ Phillips, RA Holland, ... Cell 173 (1), 140-152. e15, 2018 | 176 | 2018 |
Nutritive, post-ingestive signals are the primary regulators of AgRP neuron activity Z Su, AL Alhadeff, JN Betley Cell reports 21 (10), 2724-2736, 2017 | 166 | 2017 |
Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force S Loukin, X Zhou, Z Su, Y Saimi, C Kung Journal of Biological Chemistry 285 (35), 27176-27181, 2010 | 151 | 2010 |
Novel cell-free high-throughput screening method for pharmacological tools targeting K+ channels Z Su, EC Brown, W Wang, R MacKinnon Proceedings of the National Academy of Sciences 113 (20), 5748-5753, 2016 | 98 | 2016 |
Increased basal activity is a key determinant in the severity of human skeletal dysplasia caused by TRPV4 mutations S Loukin, Z Su, C Kung PloS one 6 (5), e19533, 2011 | 62 | 2011 |
Yeast screens show aromatic residues at the end of the sixth helix anchor transient receptor potential channel gate X Zhou, Z Su, A Anishkin, WJ Haynes, EM Friske, SH Loukin, C Kung, ... Proceedings of the National Academy of Sciences 104 (39), 15555-15559, 2007 | 56 | 2007 |
Hypotonic shocks activate rat TRPV4 in yeast in the absence of polyunsaturated fatty acids SH Loukin, Z Su, C Kung Febs Letters 583 (4), 754-758, 2009 | 52 | 2009 |
Forward genetic analysis reveals multiple gating mechanisms of TRPV4 S Loukin, Z Su, X Zhou, C Kung Journal of biological chemistry 285 (26), 19884-19890, 2010 | 49 | 2010 |
Yeast gain-of-function mutations reveal structure–function relationships conserved among different subfamilies of transient receptor potential channels Z Su, X Zhou, WJ Haynes, SH Loukin, A Anishkin, Y Saimi, C Kung Proceedings of the National Academy of Sciences 104 (49), 19607-19612, 2007 | 45 | 2007 |
Mechanical Force and Cytoplasmic Ca2+ Activate Yeast TRPY1 in Parallel Z Su, X Zhou, SH Loukin, Y Saimi, C Kung Journal of membrane biology 227, 141-150, 2009 | 39 | 2009 |
The use of yeast to understand TRP-channel mechanosensitivity Z Su, X Zhou, SH Loukin, WJ Haynes, Y Saimi, C Kung Pflügers Archiv-European Journal of Physiology 458 (5), 861-867, 2009 | 29 | 2009 |
The core domain as the force sensor of the yeast mechanosensitive TRP channel Z Su, A Anishkin, C Kung, Y Saimi Journal of General Physiology 138 (6), 627-640, 2011 | 21 | 2011 |
Indole and other aromatic compounds activate the yeast TRPY1 channel WJ Haynes, XL Zhou, ZW Su, SH Loukin, Y Saimi, C Kung FEBS letters 582 (10), 1514-1518, 2008 | 19 | 2008 |
Engineered hERG channel proteins, vesicles and methods of identifying small molecule pharmacological agents R Mackinnon, SU Zhenwei, W Wang US Patent 11,579,152, 2023 | | 2023 |
Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of CC motif chemokine receptor-like 2 (CCRL2) ligand binding function Z Su, J Brooks, J Pelker, T Andreyeva, H Sobon, R Gifford, M Powers, ... Plos one 18 (1), e0280590, 2023 | | 2023 |