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Sarel Malan
Sarel Malan
Verified email at uwc.ac.za
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Year
Pharmacology and structure‐activity relationships of bioactive polycyclic cage compounds: a focus on pentacycloundecane derivatives
WJ Geldenhuys, SF Malan, JR Bloomquist, AP Marchand, ...
Medicinal research reviews 25 (1), 21-48, 2005
2362005
Preparation and physicochemical characterization of 5 niclosamide solvates and 1 hemisolvate
EC Van Tonder, MD Mahlatji, SF Malan, W Liebenberg, MR Caira, ...
Aaps Pharmscitech 5, 86-95, 2004
1512004
Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease
J Joubert, GB Foka, BP Repsold, DW Oliver, E Kapp, SF Malan
European journal of medicinal chemistry 125, 853-864, 2017
1182017
Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues
B Strydom, SF Malan, N Castagnoli Jr, JJ Bergh, JP Petzer
Bioorganic & medicinal chemistry 18 (3), 1018-1028, 2010
1122010
Indazole derivatives and their therapeutic applications: a patent review (2013-2017)
I Denya, SF Malan, J Joubert
Expert opinion on therapeutic patents 28 (6), 441-453, 2018
1022018
Polycyclic cage structures as lipophilic scaffolds for neuroactive drugs
J Joubert, WJ Geldenhuys, CJ Van der Schyf, DW Oliver, HG Kruger, ...
ChemMedChem 7 (3), 375-384, 2012
992012
Propargylamine as functional moiety in the design of multifunctional drugs for neurodegenerative disorders: MAO inhibition and beyond
FT Zindo, J Joubert, SF Malan
Future medicinal chemistry 7 (5), 609-629, 2015
952015
Inhibition of monoamine oxidase B by selected benzimidazole and caffeine analogues
D van den Berg, KR Zoellner, MO Ogunrombi, SF Malan, G Terre’Blanche, ...
Bioorganic & medicinal chemistry 15 (11), 3692-3702, 2007
912007
Dual inhibition of monoamine oxidase B and antagonism of the adenosine A2A receptor by (E, E)-8-(4-phenylbutadien-1-yl) caffeine analogues
J Pretorius, SF Malan, N Castagnoli Jr, JJ Bergh, JP Petzer
Bioorganic & medicinal chemistry 16 (18), 8676-8684, 2008
832008
Inhibition of monoamine oxidase B by analogues of the adenosine A2A receptor antagonist (E)-8-(3-chlorostyryl) caffeine (CSC)
N Vlok, SF Malan, N Castagnoli Jr, JJ Bergh, JP Petzer
Bioorganic & medicinal chemistry 14 (10), 3512-3521, 2006
832006
Synthesis and biological evaluation of pentacyclo [5.4. 0.02, 6.03, 10.05, 9] undecane derivatives as potential therapeutic agents in Parkinson's disease
WJ Geldenhuys, SF Malan, T Murugesan, CJ Van der Schyf, ...
Bioorganic & medicinal chemistry 12 (7), 1799-1806, 2004
822004
Inhibition of monoamine oxidase by indole and benzofuran derivatives
LHA Prins, JP Petzer, SF Malan
European Journal of Medicinal Chemistry 45 (10), 4458-4466, 2010
812010
Role of monoamine oxidase, nitric oxide synthase and regional brain monoamines in the antidepressant-like effects of methylene blue and selected structural analogues
BH Harvey, I Duvenhage, F Viljoen, N Scheepers, SF Malan, G Wegener, ...
Biochemical pharmacology 80 (10), 1580-1591, 2010
762010
Medicinal chemistry of polycyclic cage compounds in drug discovery research
DW Oliver, SF Malan
Medicinal Chemistry Research 17, 137-151, 2008
712008
Structure–activity relationships of pentacycloundecylamines at the N-methyl-d-aspartate receptor
WJ Geldenhuys, SF Malan, JR Bloomquist, CJ Van der Schyf
Bioorganic & medicinal chemistry 15 (3), 1525-1532, 2007
692007
Antioxidant properties of 4-quinolones and structurally related flavones
J Greeff, J Joubert, SF Malan, S van Dyk
Bioorganic & medicinal chemistry 20 (2), 809-818, 2012
672012
Anti-inflammatory activity and QSAR studies of compounds isolated from Hyacinthaceae species and Tachiadenus longiflorus Griseb.(Gentianaceae)
K du Toit, EE Elgorashi, SF Malan, SE Drewes, J van Staden, NR Crouch, ...
Bioorganic & medicinal chemistry 13 (7), 2561-2568, 2005
622005
Inhibition of monoamine oxidase by (E)-styrylisatin analogues
EM Van der Walt, EM Milczek, SF Malan, DE Edmondson, N Castagnoli Jr, ...
Bioorganic & medicinal chemistry letters 19 (9), 2509-2513, 2009
562009
Physicochemical prediction of a brain–blood distribution profile in polycyclic amines
J Zah, G Terre'Blanche, E Erasmus, SF Malan
Bioorganic & medicinal chemistry 11 (17), 3569-3578, 2003
562003
Quantitative structure–activity relationship studies on acetylcholinesterase enzyme inhibitory effects of Amaryllidaceae alkaloids
EE Elgorashi, SF Malan, GI Stafford, J Van Staden
South African Journal of Botany 72 (2), 224-231, 2006
552006
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