| Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA MC Liu, GR Oxnard, EA Klein, C Swanton, MV Seiden, MC Liu, ... Annals of Oncology 31 (6), 745-759, 2020 | 977 | 2020 |
| EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation W Béguelin, R Popovic, M Teater, Y Jiang, KL Bunting, M Rosen, H Shen, ... Cancer cell 23 (5), 677-692, 2013 | 910 | 2013 |
| The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ... Nature medicine 21 (10), 1199-1208, 2015 | 425 | 2015 |
| EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis I Velichutina, R Shaknovich, H Geng, NA Johnson, RD Gascoyne, ... Blood, The Journal of the American Society of Hematology 116 (24), 5247-5255, 2010 | 374 | 2010 |
| Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas BB Ding, JJ Yu, RYL Yu, LM Mendez, R Shaknovich, Y Zhang, G Cattoretti, ... Blood, The Journal of the American Society of Hematology 111 (3), 1515-1523, 2008 | 352 | 2008 |
| The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL W Ci, JM Polo, L Cerchietti, R Shaknovich, L Wang, SN Yang, K Ye, ... Blood, The Journal of the American Society of Hematology 113 (22), 5536-5548, 2009 | 270 | 2009 |
| MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo L Fontan, C Yang, V Kabaleeswaran, L Volpon, MJ Osborne, E Beltran, ... Cancer cell 22 (6), 812-824, 2012 | 265 | 2012 |
| CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas Y Jiang, A Ortega-Molina, H Geng, HY Ying, K Hatzi, S Parsa, D McNally, ... Cancer discovery 7 (1), 38-53, 2017 | 258 | 2017 |
| EZH2 and BCL6 cooperate to assemble CBX8-BCOR complex to repress bivalent promoters, mediate germinal center formation and lymphomagenesis W Béguelin, M Teater, MD Gearhart, MTC Fernández, RL Goldstein, ... Cancer cell 30 (2), 197-213, 2016 | 234 | 2016 |
| TET1 is a tumor suppressor of hematopoietic malignancy L Cimmino, MM Dawlaty, D Ndiaye-Lobry, YS Yap, S Bakogianni, Y Yu, ... Nature immunology 16 (6), 653-662, 2015 | 228 | 2015 |
| Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A PL Yeyati, R Shaknovich, S Boterashvili, J Li, HJ Ball, S Waxman, ... Oncogene 18 (4), 925-934, 1999 | 221 | 1999 |
| The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma E Oricchio, G Nanjangud, AL Wolfe, JH Schatz, KJ Mavrakis, M Jiang, ... Cell 147 (3), 554-564, 2011 | 220 | 2011 |
| Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma T Clozel, SN Yang, RL Elstrom, W Tam, P Martin, M Kormaksson, ... Cancer discovery 3 (9), 1002-1019, 2013 | 217 | 2013 |
| Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells G Cattoretti, M Büttner, R Shaknovich, E Kremmer, B Alobeid, ... Blood 107 (10), 3967-3975, 2006 | 216 | 2006 |
| The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosis R Shaknovich, PL Yeyati, S Ivins, A Melnick, C Lempert, S Waxman, ... Molecular and cellular biology 18 (9), 5533-5545, 1998 | 209 | 1998 |
| A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6–dependent B cell lymphomas LC Cerchietti, EC Lopes, SN Yang, K Hatzi, KL Bunting, LA Tsikitas, ... Nature medicine 15 (12), 1369-1376, 2009 | 207 | 2009 |
| A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo LC Cerchietti, SN Yang, R Shaknovich, K Hatzi, JM Polo, A Chadburn, ... Blood, The Journal of the American Society of Hematology 113 (15), 3397-3405, 2009 | 198 | 2009 |
| Conformational activation of a basic helix-loop-helix protein (MyoDl) by the C-terminal region of murine HSP90 (HSP84) R Shaknovich, G Shue, D Stave Kohtz Molecular and cellular biology 12 (11), 5059-5068, 1992 | 189 | 1992 |
| CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer CJ Kemp, JM Moore, R Moser, B Bernard, M Teater, LE Smith, NA Rabaia, ... Cell reports 7 (4), 1020-1029, 2014 | 182 | 2014 |
| BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms S Parekh, JM Polo, R Shaknovich, P Juszczynski, P Lev, SM Ranuncolo, ... Blood, The Journal of the American Society of Hematology 110 (6), 2067-2074, 2007 | 174 | 2007 |
Olivier ElementoDirector, Englander Institute for Precision Medicine, Weill Cornell MedicineVerified email at med.cornell.edu
