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Sean Moran
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How to get insight into amyloid structure and formation from infrared spectroscopy
SD Moran, MT Zanni
The journal of physical chemistry letters 5 (11), 1984-1993, 2014
2372014
Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy
HT Kratochvil, JK Carr, K Matulef, AW Annen, H Li, M Maj, J Ostmeyer, ...
Science 353 (6303), 1040-1044, 2016
2042016
Two-dimensional IR spectroscopy and segmental 13C labeling reveals the domain structure of human γD-crystallin amyloid fibrils
SD Moran, AM Woys, LE Buchanan, E Bixby, SM Decatur, MT Zanni
Proceedings of the National Academy of Sciences 109 (9), 3329-3334, 2012
1522012
Structural motif of polyglutamine amyloid fibrils discerned with mixed-isotope infrared spectroscopy
LE Buchanan, JK Carr, AM Fluitt, AJ Hoganson, SD Moran, JJ de Pablo, ...
Proceedings of the National Academy of Sciences 111 (16), 5796-5801, 2014
1242014
Amyloid fiber formation in human γD-crystallin induced by UV–B photodamage
SD Moran, TO Zhang, SM Decatur, MT Zanni
Biochemistry 52 (36), 6169-6181, 2013
602013
A strongly absorbing class of non-natural labels for probing protein electrostatics and solvation with FTIR and 2D IR spectroscopies
AM Woys, SS Mukherjee, DR Skoff, SD Moran, MT Zanni
The journal of physical chemistry B 117 (17), 5009-5018, 2013
562013
Structural and Sequence Analysis of the Human γD-Crystallin Amyloid Fibril Core Using 2D IR Spectroscopy, Segmental 13C Labeling, and Mass Spectrometry
SD Moran, SM Decatur, MT Zanni
Journal of the American Chemical Society 134 (44), 18410-18416, 2012
452012
An alternative structural isoform in amyloid‐like aggregates formed from thermally denatured human γD‐crystallin
SD Moran, TO Zhang, MT Zanni
Protein Science 23 (3), 321-331, 2014
232014
Study of the γD-crystallin protein using two-dimensional infrared (2DIR) spectroscopy: experiment and simulation
AR Lam, SD Moran, NK Preketes, TO Zhang, MT Zanni, S Mukamel
The Journal of Physical Chemistry B 117 (49), 15436-15443, 2013
112013
Making a single-chain four-helix bundle for redox chemistry studies
K Westerlund, SD Moran, HK Privett, S Hay, J Jarvet, BR Gibney, ...
Protein Engineering, Design & Selection 21 (11), 645-652, 2008
112008
Infrared spectroscopy reveals the preferred motif size and local disorder in parallel stranded DNA G‐quadruplexes
DA Price, ZJ Kartje, JA Hughes, TD Hill, TM Loth, JK Watts, KT Gagnon, ...
ChemBioChem 21 (19), 2792-2804, 2020
82020
Isotope-Labeled Amyloids via Synthesis, Expression, and Chemical Ligation for Use in FTIR, 2D IR, and NMR Studies
TO Zhang, M Grechko, SD Moran, MT Zanni
Protein Amyloid Aggregation: Methods and Protocols, 21-41, 2016
82016
The polarization dependence of 2D IR cross-peaks distinguishes parallel-stranded and antiparallel-stranded DNA G-quadruplexes
DA Price, P Wedamulla, TD Hill, TM Loth, SD Moran
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 267, 120596, 2022
52022
Effects of the Intramolecular Group and Solvent on Vibrational Coupling Modes and Strengths of Fermi Resonances in Aryl Azides: A DFT Study of 4-Azidotoluene and 4-Azido-N …
SM Perera, T Aikawa, SE Shaner, SD Moran, L Wang
The Journal of Physical Chemistry A 127 (42), 8911-8921, 2023
22023
Investigating the effects of protein structural context and hydrophobic burial on the thermodynamic selectivity and reactivity of tryptophan indole and mononuclear metal ion …
SD Moran
Columbia University, 2008
22008
Binding to the conserved and stably folded guide RNA pseudoknot induces Cas12a conformational changes during ribonucleoprotein assembly
S Sudhakar, CL Barkau, R Chilamkurthy, HM Barber, AA Pater, SD Moran, ...
Journal of Biological Chemistry 299 (5), 2023
12023
Investigating Protein Aggregation using Segmental Isotope Labeling and 2D IR Spectroscopy
SD Moran, E Bixby, SM Decatur, MT Zanni
Biophysical Journal 100 (3), 531a-532a, 2011
12011
Ultrafast 2D IR Studies of Internal Hydrogen Bonding Dynamics in Enzymes: The Influence of Substrate and Inhibitor Binding
S Moran
Bulletin of the American Physical Society, 2024
2024
Anisotropic dynamics of an interfacial enzyme active site observed using tethered substrate analogs and ultrafast 2D IR spectroscopy
TD Hill, S Basnet, HH Lepird, BW Rightnowar, SD Moran
The Journal of Chemical Physics 159 (16), 2023
2023
Examining enzyme active site dynamics using linear and nonlinear infrared spectroscopy: substrate orientation, cofactor composition, and solvent effects
S Basnet, HH Lepird, TD Hill, SD Moran
Biophysical Journal 121 (3), 53a-54a, 2022
2022
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