pHLIP-mediated translocation of membrane-impermeable molecules into cells D Thévenin, M An, DM Engelman Chemistry & biology 16 (7), 754-762, 2009 | 91 | 2009 |
Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulation EE Matthews, D Thévenin, JM Rogers, L Gotow, PD Lira, LA Reiter, ... The FASEB Journal 25 (7), 2234, 2011 | 84 | 2011 |
Oligomerization of the fifth transmembrane domain from the adenosine A2A receptor D Thevenin, T Lazarova, MF Roberts, CR Robinson Protein science 14 (8), 2177-2186, 2005 | 70 | 2005 |
Inhibition of cancer cell proliferation and breast tumor targeting of pHLIP–monomethyl auristatin E conjugates KE Burns, MK Robinson, D Thévenin Molecular pharmaceutics 12 (4), 1250-1258, 2015 | 64 | 2015 |
pH-selective cytotoxicity of pHLIP-antimicrobial peptide conjugates KE Burns, TP McCleerey, D Thévenin Scientific reports 6 (1), 28465, 2016 | 62 | 2016 |
Taming amphotericin B V Janout, WA Schell, D Thévenin, Y Yu, JR Perfect, SL Regen Bioconjugate chemistry 26 (10), 2021-2024, 2015 | 42 | 2015 |
Comparison of lipid-dependent bilayer insertion of pHLIP and its P20G variant V Vasquez-Montes, J Gerhart, KE King, D Thévenin, AS Ladokhin Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (2), 534-543, 2018 | 38 | 2018 |
Therapeutic efficacy of a family of pHLIP–MMAF conjugates in cancer cells and mouse models KE Burns, H Hensley, MK Robinson, D Thévenin Molecular pharmaceutics 14 (2), 415-422, 2017 | 35 | 2017 |
Stable interactions between the transmembrane domains of the adenosine A2A receptor D Thévenin, T Lazarova Protein Science 17 (7), 1188-1199, 2008 | 33 | 2008 |
Identifying Interactions between Transmembrane Helices from the Adenosine A2A Receptor D Thévenin, MF Roberts, T Lazarova, CR Robinson Biochemistry 44 (49), 16239-16245, 2005 | 32 | 2005 |
Down-regulation of PAR1 activity with a pHLIP-based allosteric antagonist induces cancer cell death KE Burns, D Thévenin Biochemical Journal 472 (3), 287-295, 2015 | 31 | 2015 |
Divalent cations and lipid composition modulate membrane insertion and cancer-targeting action of pHLIP V Vasquez-Montes, J Gerhart, D Thévenin, AS Ladokhin Journal of molecular biology 431 (24), 5004-5018, 2019 | 27 | 2019 |
Peptide targeting and imaging of damaged lung tissue in influenza-infected mice N Li, L Yin, D Thévenin, Y Yamada, G Limmon, J Chen, VTK Chow, ... Future microbiology 8 (2), 257-269, 2013 | 26 | 2013 |
Inhibiting epidermal growth factor receptor dimerization and signaling through targeted delivery of a juxtamembrane domain peptide mimic J Gerhart, AF Thévenin, E Bloch, KE King, D Thévenin ACS chemical biology 13 (9), 2623-2632, 2018 | 21 | 2018 |
Disrupting the transmembrane domain–mediated oligomerization of protein tyrosine phosphatase receptor J inhibits EGFR-driven cancer cell phenotypes E Bloch, EL Sikorski, D Pontoriero, EK Day, BW Berger, MJ Lazzara, ... Journal of Biological Chemistry 294 (49), 18796-18806, 2019 | 17 | 2019 |
Conjugates of pH Low Insertion Peptide and Monomethyl Auristatins in the Treatment of Solid Tumors D Thevenin, MK Robinson, KE Burns US Patent App. 15/449,318, 2017 | 11 | 2017 |
Ph-dependent grafting of cancer cells with antigenic epitopes promotes selective antibody-mediated cytotoxicity J Wehr, EL Sikorski, E Bloch, MS Feigman, NJ Ferraro, TR Baybutt, ... Journal of medicinal chemistry 63 (7), 3713-3722, 2020 | 10 | 2020 |
Ca2+‐dependent interactions between lipids and the tumor‐targeting peptide pHLIP V Vasquez‐Montes, V Tyagi, E Sikorski, A Kyrychenko, JA Freites, ... Protein Science 31 (9), e4385, 2022 | 8 | 2022 |
Identifying and measuring transmembrane helix–helix interactions by FRET D Thévenin, T Lazarova Membrane Protein Structure and Dynamics: Methods and Protocols, 87-106, 2012 | 6 | 2012 |
Backscattering Interferometry: Seeing Membrane Proteins in a New Light J Gerhart, G Haddad-Weiser, A Kussrow, D Bornhop, R Flowers, ... Biophysical Journal 108 (2), 253a, 2015 | 5 | 2015 |