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Damien Thévenin
Damien Thévenin
Associate Professor of Chemistry, Lehigh University
Verified email at lehigh.edu - Homepage
Title
Cited by
Cited by
Year
pHLIP-mediated translocation of membrane-impermeable molecules into cells
D Thévenin, M An, DM Engelman
Chemistry & biology 16 (7), 754-762, 2009
912009
Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulation
EE Matthews, D Thévenin, JM Rogers, L Gotow, PD Lira, LA Reiter, ...
The FASEB Journal 25 (7), 2234, 2011
842011
Oligomerization of the fifth transmembrane domain from the adenosine A2A receptor
D Thevenin, T Lazarova, MF Roberts, CR Robinson
Protein science 14 (8), 2177-2186, 2005
702005
Inhibition of cancer cell proliferation and breast tumor targeting of pHLIP–monomethyl auristatin E conjugates
KE Burns, MK Robinson, D Thévenin
Molecular pharmaceutics 12 (4), 1250-1258, 2015
642015
pH-selective cytotoxicity of pHLIP-antimicrobial peptide conjugates
KE Burns, TP McCleerey, D Thévenin
Scientific reports 6 (1), 28465, 2016
622016
Taming amphotericin B
V Janout, WA Schell, D Thévenin, Y Yu, JR Perfect, SL Regen
Bioconjugate chemistry 26 (10), 2021-2024, 2015
422015
Comparison of lipid-dependent bilayer insertion of pHLIP and its P20G variant
V Vasquez-Montes, J Gerhart, KE King, D Thévenin, AS Ladokhin
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (2), 534-543, 2018
382018
Therapeutic efficacy of a family of pHLIP–MMAF conjugates in cancer cells and mouse models
KE Burns, H Hensley, MK Robinson, D Thévenin
Molecular pharmaceutics 14 (2), 415-422, 2017
352017
Stable interactions between the transmembrane domains of the adenosine A2A receptor
D Thévenin, T Lazarova
Protein Science 17 (7), 1188-1199, 2008
332008
Identifying Interactions between Transmembrane Helices from the Adenosine A2A Receptor
D Thévenin, MF Roberts, T Lazarova, CR Robinson
Biochemistry 44 (49), 16239-16245, 2005
322005
Down-regulation of PAR1 activity with a pHLIP-based allosteric antagonist induces cancer cell death
KE Burns, D Thévenin
Biochemical Journal 472 (3), 287-295, 2015
312015
Divalent cations and lipid composition modulate membrane insertion and cancer-targeting action of pHLIP
V Vasquez-Montes, J Gerhart, D Thévenin, AS Ladokhin
Journal of molecular biology 431 (24), 5004-5018, 2019
272019
Peptide targeting and imaging of damaged lung tissue in influenza-infected mice
N Li, L Yin, D Thévenin, Y Yamada, G Limmon, J Chen, VTK Chow, ...
Future microbiology 8 (2), 257-269, 2013
262013
Inhibiting epidermal growth factor receptor dimerization and signaling through targeted delivery of a juxtamembrane domain peptide mimic
J Gerhart, AF Thévenin, E Bloch, KE King, D Thévenin
ACS chemical biology 13 (9), 2623-2632, 2018
212018
Disrupting the transmembrane domain–mediated oligomerization of protein tyrosine phosphatase receptor J inhibits EGFR-driven cancer cell phenotypes
E Bloch, EL Sikorski, D Pontoriero, EK Day, BW Berger, MJ Lazzara, ...
Journal of Biological Chemistry 294 (49), 18796-18806, 2019
172019
Conjugates of pH Low Insertion Peptide and Monomethyl Auristatins in the Treatment of Solid Tumors
D Thevenin, MK Robinson, KE Burns
US Patent App. 15/449,318, 2017
112017
Ph-dependent grafting of cancer cells with antigenic epitopes promotes selective antibody-mediated cytotoxicity
J Wehr, EL Sikorski, E Bloch, MS Feigman, NJ Ferraro, TR Baybutt, ...
Journal of medicinal chemistry 63 (7), 3713-3722, 2020
102020
Ca2+‐dependent interactions between lipids and the tumor‐targeting peptide pHLIP
V Vasquez‐Montes, V Tyagi, E Sikorski, A Kyrychenko, JA Freites, ...
Protein Science 31 (9), e4385, 2022
82022
Identifying and measuring transmembrane helix–helix interactions by FRET
D Thévenin, T Lazarova
Membrane Protein Structure and Dynamics: Methods and Protocols, 87-106, 2012
62012
Backscattering Interferometry: Seeing Membrane Proteins in a New Light
J Gerhart, G Haddad-Weiser, A Kussrow, D Bornhop, R Flowers, ...
Biophysical Journal 108 (2), 253a, 2015
52015
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