Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells Z Bian, L Shi, YL Guo, Z Lv, C Tang, S Niu, A Tremblay, M Venkataramani, ... Proceedings of the National Academy of Sciences 113 (37), E5434-E5443, 2016 | 128 | 2016 |
Broad infiltration of macrophages leads to a proinflammatory state in streptozotocin-induced hyperglycemic mice S Niu, Z Bian, A Tremblay, Y Luo, K Kidder, A Mansour, K Zen, Y Liu The Journal of Immunology 197 (8), 3293-3301, 2016 | 64 | 2016 |
Arginase‐1 is neither constitutively expressed in nor required for myeloid‐derived suppressor cell‐mediated inhibition of T‐cell proliferation Z Bian, AM Abdelaal, L Shi, H Liang, L Xiong, K Kidder, M Venkataramani, ... European journal of immunology 48 (6), 1046-1058, 2018 | 55 | 2018 |
Tumor conditions induce bone marrow expansion of granulocytic, but not monocytic, immunosuppressive leukocytes with increased CXCR2 expression in mice Z Bian, L Shi, M Venkataramani, AM Abdelaal, C Culpepper, K Kidder, ... European journal of immunology 48 (3), 532-542, 2018 | 32 | 2018 |
Enhancing microRNA activity through increased endosomal release mediated by nigericin EA Orellana, AM Abdelaal, L Rangasamy, S Tenneti, S Myoung, PS Low, ... Molecular Therapy-Nucleic Acids 16, 505-518, 2019 | 29 | 2019 |
Ligand-mediated delivery of RNAi-based therapeutics for the treatment of oncological diseases AM Abdelaal, AL Kasinski NAR cancer 3 (3), zcab030, 2021 | 19 | 2021 |
A first-in-class fully modified version of miR-34a with outstanding stability, activity, and anti-tumor efficacy AM Abdelaal, IS Sohal, S Iyer, K Sudarshan, H Kothandaraman, ... Oncogene 42 (40), 2985-2999, 2023 | 14 | 2023 |
Induction of arginase-1 in MDSC requires exposure to CD3/CD28 activated T cells AA Abdelaal, Z Bian, C Culpepper, Y Liu J Immunol May 2017, 198 (1 Supplement) 154.13;, 2017 | 5 | 2017 |
Developing Folate-Conjugated miR-34a Therapeutic for Prostate Cancer: Challenges and Promises W Li, Y Wang, X Liu, S Wu, M Wang, SG Turowski, JA Spernyak, A Tracz, ... International Journal of Molecular Sciences 25 (4), 2123, 2024 | 2 | 2024 |
Selective targeting of chemically modified miR-34a to prostate cancer using a small molecule ligand and an endosomal escape agent AM Abdelaal, IS Sohal, SG Iyer, K Sudarshan, EA Orellana, KE Ozcan, ... Molecular Therapy-Nucleic Acids, 2024 | | 2024 |
ENHANCING MIRNA THERAPEUTICS USING LIGAND CONJUGATED AND CHEMICALLY MODIFIED TUMOR SUPPRESSIVE MIRNAS AM Abdelaal Purdue University Graduate School, 2023 | | 2023 |
Further development of microRNA-34a therapeutics to target castration-resistant prostate cancer W Li, X Liu, AM Abdelaal, S Kasireddy, Y Su, Y Wu, AL Kasinski, DG Tang Cancer Research 83 (7_Supplement), 2716-2716, 2023 | | 2023 |
Targeting cancer cells using folate conjugated to a fully modified version of miR-34a (FolamiR-34a) to produce enhanced and sustained anti-tumor activity SG Iyer, AM Abdelaal, IS Sohal, SR Kasireddy, AL Kasinski Cancer Research 83 (7_Supplement), 3782-3782, 2023 | | 2023 |
Determining the intracellular fate of ligand-conjugated therapeutics using nanogold labeling IS Sohal, AM Abdelaal, AL Kasinski Cancer Research 82 (12_Supplement), 1740-1740, 2022 | | 2022 |
Efficient targeting of prostate cancer using ligand conjugated and chemically modified tumor suppressive miRNA AM Abdelaal, S Kasireddy, IS Sohal, PS Low, AL Kasinski Cancer Research 82 (12_Supplement), 1482-1482, 2022 | | 2022 |
5-methyltetrahydrofolate (5-MTHF) as a superior ligand for delivery of small RNAs for cancer therapy SR Kasireddy, AM Abdelaal, PS Low, AL Kasinski Cancer Research 82 (12_Supplement), 1494-1494, 2022 | | 2022 |
Induction Of Arginase-1 In MDSC Requires Exposure to CD3/CD28 Activated T Cells A Abdelbaky Abdelaal | | 2017 |