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Ahmed M Abdelaal
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Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells
Z Bian, L Shi, YL Guo, Z Lv, C Tang, S Niu, A Tremblay, M Venkataramani, ...
Proceedings of the National Academy of Sciences 113 (37), E5434-E5443, 2016
1282016
Broad infiltration of macrophages leads to a proinflammatory state in streptozotocin-induced hyperglycemic mice
S Niu, Z Bian, A Tremblay, Y Luo, K Kidder, A Mansour, K Zen, Y Liu
The Journal of Immunology 197 (8), 3293-3301, 2016
642016
Arginase‐1 is neither constitutively expressed in nor required for myeloid‐derived suppressor cell‐mediated inhibition of T‐cell proliferation
Z Bian, AM Abdelaal, L Shi, H Liang, L Xiong, K Kidder, M Venkataramani, ...
European journal of immunology 48 (6), 1046-1058, 2018
552018
Tumor conditions induce bone marrow expansion of granulocytic, but not monocytic, immunosuppressive leukocytes with increased CXCR2 expression in mice
Z Bian, L Shi, M Venkataramani, AM Abdelaal, C Culpepper, K Kidder, ...
European journal of immunology 48 (3), 532-542, 2018
322018
Enhancing microRNA activity through increased endosomal release mediated by nigericin
EA Orellana, AM Abdelaal, L Rangasamy, S Tenneti, S Myoung, PS Low, ...
Molecular Therapy-Nucleic Acids 16, 505-518, 2019
292019
Ligand-mediated delivery of RNAi-based therapeutics for the treatment of oncological diseases
AM Abdelaal, AL Kasinski
NAR cancer 3 (3), zcab030, 2021
192021
A first-in-class fully modified version of miR-34a with outstanding stability, activity, and anti-tumor efficacy
AM Abdelaal, IS Sohal, S Iyer, K Sudarshan, H Kothandaraman, ...
Oncogene 42 (40), 2985-2999, 2023
142023
Induction of arginase-1 in MDSC requires exposure to CD3/CD28 activated T cells
AA Abdelaal, Z Bian, C Culpepper, Y Liu
J Immunol May 2017, 198 (1 Supplement) 154.13;, 2017
52017
Developing Folate-Conjugated miR-34a Therapeutic for Prostate Cancer: Challenges and Promises
W Li, Y Wang, X Liu, S Wu, M Wang, SG Turowski, JA Spernyak, A Tracz, ...
International Journal of Molecular Sciences 25 (4), 2123, 2024
22024
Selective targeting of chemically modified miR-34a to prostate cancer using a small molecule ligand and an endosomal escape agent
AM Abdelaal, IS Sohal, SG Iyer, K Sudarshan, EA Orellana, KE Ozcan, ...
Molecular Therapy-Nucleic Acids, 2024
2024
ENHANCING MIRNA THERAPEUTICS USING LIGAND CONJUGATED AND CHEMICALLY MODIFIED TUMOR SUPPRESSIVE MIRNAS
AM Abdelaal
Purdue University Graduate School, 2023
2023
Further development of microRNA-34a therapeutics to target castration-resistant prostate cancer
W Li, X Liu, AM Abdelaal, S Kasireddy, Y Su, Y Wu, AL Kasinski, DG Tang
Cancer Research 83 (7_Supplement), 2716-2716, 2023
2023
Targeting cancer cells using folate conjugated to a fully modified version of miR-34a (FolamiR-34a) to produce enhanced and sustained anti-tumor activity
SG Iyer, AM Abdelaal, IS Sohal, SR Kasireddy, AL Kasinski
Cancer Research 83 (7_Supplement), 3782-3782, 2023
2023
Determining the intracellular fate of ligand-conjugated therapeutics using nanogold labeling
IS Sohal, AM Abdelaal, AL Kasinski
Cancer Research 82 (12_Supplement), 1740-1740, 2022
2022
Efficient targeting of prostate cancer using ligand conjugated and chemically modified tumor suppressive miRNA
AM Abdelaal, S Kasireddy, IS Sohal, PS Low, AL Kasinski
Cancer Research 82 (12_Supplement), 1482-1482, 2022
2022
5-methyltetrahydrofolate (5-MTHF) as a superior ligand for delivery of small RNAs for cancer therapy
SR Kasireddy, AM Abdelaal, PS Low, AL Kasinski
Cancer Research 82 (12_Supplement), 1494-1494, 2022
2022
Induction Of Arginase-1 In MDSC Requires Exposure to CD3/CD28 Activated T Cells
A Abdelbaky Abdelaal
2017
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Articles 1–17