Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation M Diaconu, U Kothe, F Schlünzen, N Fischer, JM Harms, AG Tonevitsky, ... Cell 121 (7), 991-1004, 2005 | 473 | 2005 |
Recognition and selection of tRNA in translation MV Rodnina, KB Gromadski, U Kothe, HJ Wieden FEBS letters 579 (4), 938-942, 2005 | 214 | 2005 |
Eukaryotic stand-alone pseudouridine synthases–RNA modifying enzymes and emerging regulators of gene expression? AC Rintala-Dempsey, U Kothe RNA biology 14 (9), 1185-1196, 2017 | 143 | 2017 |
Control of phosphate release from elongation factor G by ribosomal protein L7/12 A Savelsbergh, D Mohr, U Kothe, W Wintermeyer, MV Rodnina The EMBO Journal 24 (24), 4316-4323, 2005 | 123 | 2005 |
Interaction of helix D of elongation factor Tu with helices 4 and 5 of protein L7/12 on the ribosome U Kothe, HJ Wieden, D Mohr, MV Rodnina Journal of molecular biology 336 (5), 1011-1021, 2004 | 104 | 2004 |
Delayed release of inorganic phosphate from elongation factor Tu following GTP hydrolysis on the ribosome U Kothe, MV Rodnina Biochemistry 45 (42), 12767-12774, 2006 | 85 | 2006 |
RNA modification enzyme TruB is a tRNA chaperone LC Keffer-Wilkes, GR Veerareddygari, U Kothe Proceedings of the National Academy of Sciences 113 (50), 14306-14311, 2016 | 79 | 2016 |
Codon reading by tRNAAla with modified uridine in the wobble position U Kothe, MV Rodnina Molecular cell 25 (1), 167-174, 2007 | 76 | 2007 |
Efficient RNA pseudouridylation by eukaryotic H/ACA ribonucleoproteins requires high affinity binding and correct positioning of guide RNA EA Caton, EK Kelly, R Kamalampeta, U Kothe Nucleic acids research 46 (2), 905-916, 2018 | 44 | 2018 |
Pre-steady-state kinetic analysis of the three Escherichia coli pseudouridine synthases TruB, TruA, and RluA reveals uniformly slow catalysis JR Wright, LC Keffer-Wilkes, SR Dobing, U Kothe Rna 17 (12), 2074-2084, 2011 | 42 | 2011 |
The methyltransferase TrmA facilitates tRNA folding through interaction with its RNA-binding domain LC Keffer-Wilkes, EF Soon, U Kothe Nucleic acids research 48 (14), 7981-7990, 2020 | 34 | 2020 |
Archaeal proteins Nop10 and Gar1 increase the catalytic activity of Cbf5 in pseudouridylating tRNA R Kamalampeta, U Kothe Scientific reports 2 (1), 663, 2012 | 32 | 2012 |
Base-pairing interactions between substrate RNA and H/ACA guide RNA modulate the kinetics of pseudouridylation, but not the affinity of substrate binding by H/ACA small … EK Kelly, DP Czekay, U Kothe Rna 25 (10), 1393-1404, 2019 | 29 | 2019 |
H/ACA small ribonucleoproteins: structural and functional comparison between archaea and eukaryotes DP Czekay, U Kothe Frontiers in Microbiology 12, 654370, 2021 | 28 | 2021 |
Single-step purification of specific tRNAs by hydrophobic tagging. U Kothe, A Paleskava, AL Konevega, MV Rodnina Analytical biochemistry 356 (1), 148-150, 2006 | 27 | 2006 |
An arginine-aspartate network in the active site of bacterial TruB is critical for catalyzing pseudouridine formation J Friedt, FMV Leavens, E Mercier, HJ Wieden, U Kothe Nucleic Acids Research 42 (6), 3857-3870, 2014 | 24 | 2014 |
tRNA binding, positioning, and modification by the pseudouridine synthase Pus10 R Kamalampeta, LC Keffer-Wilkes, U Kothe Journal of molecular biology 425 (20), 3863-3874, 2013 | 23 | 2013 |
tRNA elbow modifications affect the tRNA pseudouridine synthase TruB and the methyltransferase TrmA SKL Schultz, U Kothe Rna 26 (9), 1131-1142, 2020 | 22 | 2020 |
Revisiting tRNA chaperones: new players in an ancient game J Porat, U Kothe, MA Bayfield Rna 27 (5), 543-559, 2021 | 21 | 2021 |
The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface J Guegueniat, L Halabelian, H Zeng, A Dong, Y Li, H Wu, CH Arrowsmith, ... Nucleic acids research 49 (20), 11810-11822, 2021 | 14 | 2021 |