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Chao Xu
Chao Xu
Verified email at roswellpark.org
Title
Cited by
Cited by
Year
The epichaperome is an integrated chaperome network that facilitates tumour survival
Nature 538, 397-401, 2016
2472016
Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 response
CD Fan, MA Lum, C Xu, JD Black, X Wang
Journal of Biological Chemistry 288 (3), 1674-1684, 2013
1222013
Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase
C Xu, CD Fan, X Wang
Oncogene 34 (3), 281-289, 2015
882015
FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX
X Ling, C Xu, C Fan, K Zhong, F Li, X Wang
Cancer research 74 (24), 7487-7497, 2014
652014
HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons
S Kishinevsky, T Wang, A Rodina, SY Chung, C Xu, J Philip, T Taldone, ...
Nature communications 9 (1), 4345, 2018
432018
Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells
Wu W, Xu C, Ling X, Fan C, Buckley BP, Chernov MV, Ellis L, Li F, Muñoz IG ...
Cell Death Dis., 2015
282015
Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
S Joshi, EDG Gomes, T Wang, A Corben, T Taldone, S Gandu, C Xu, ...
Communications Biology 4 (1), 1333, 2021
122021
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
A Rodina, C Xu, CS Digwal, S Joshi, Y Patel, AR Santhaseela, S Bay, ...
Nature communications 14 (1), 3742, 2023
82023
The interaction of azurin and C-terminal domain of p53 is mediated by nucleic acids
Xu C, Zhao Y, Zhao B
Arch Biochem Biophys 503, 2010
72010
Structural characteristics of the hydrophobic patch of azurin and its interaction with p53: a site-directed spin labeling study
Xu C, Yin J, Zhao B
Sci China Life Sci 53, 2010
62010
Epichaperomics can identify disease-related changes in protein-protein interaction networks
A Rodina, C Xu, C Digwal, S Joshi, AS Seela, S Bay, S Merugu, A Alam, ...
2023
Allosteric Hsp70-family inhibitors as targeted anticancer therapeutics
J Koren, C Xu, A Rodina, L Shrestha, T Taldone, G Chiosis
Cancer Research 75 (15_Supplement), 1740-1740, 2015
2015
Ubiquitin-dependent regulation of AKT by NEDD4-1.
X Wang, CD Fan, MA Lum, C Xu, JD Black
Cancer Research 73 (8_Supplement), 5157-5157, 2013
2013
NEDD4–1‐mediated ubiquitination regulates pAKT nuclear trafficking in IGF‐1 response
X Wang, CD Fan, MA Lum, C Xu, JD Black
The FASEB Journal 27, 556.1-556.1, 2013
2013
UBIQUITIN-DEPENDENT REGULATION OF PHOSPHO-AKT DYNAMICS BY THE UBIQUITIN E3 LIGASE, NEDD4-1, IN THE IGF-1
CD Fan, MA Lum, C Xu, JD Black, X Wang
2012
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