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Arpit Doshi
Arpit Doshi
Astraea Therapeutics LLC
Verified email at astraeatherapeutics.com
Title
Cited by
Cited by
Year
Catalytic isonitrile insertions and condensations initiated by RNC–X complexation
S Chakrabarty, S Choudhary, A Doshi, FQ Liu, R Mohan, MP Ravindra, ...
Advanced synthesis & catalysis 356 (10), 2135-2196, 2014
1392014
Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy
AS Dekhne, K Shah, GS Ducker, JM Katinas, J Wong-Roushar, ...
Molecular cancer therapeutics 18 (10), 1787-1799, 2019
462019
AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization
A Bastian, S Matsuzaki, KM Humphries, GA Pharaoh, A Doshi, N Zaware, ...
Cancer letters 388, 149-157, 2017
452017
Structural and enzymatic analysis of tumor-targeted antifolates that inhibit glycinamide ribonucleotide formyltransferase
SM Deis, A Doshi, Z Hou, LH Matherly, A Gangjee, CE Dann III
Biochemistry 55 (32), 4574-4582, 2016
262016
Design, Synthesis, and Biological Evaluation of 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines as Microtubule Targeting Agents
F Islam, A Doshi, AJ Robles, TM Quadery, X Zhang, X Zhou, E Hamel, ...
Molecules 27 (1), 321, 2022
52022
Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer
S Choudhary, A Doshi, L Luckett-Chastain, M Ihnat, E Hamel, ...
Bioorganic & medicinal chemistry 35, 116061, 2021
42021
Structure-based SAR in the design of selective or bifunctional nociceptin (NOP) receptor agonists
ME Meyer, A Doshi, D Yasuda, NT Zaveri
The AAPS Journal 23 (3), 68, 2021
22021
Discovery of amide-bridged pyrrolo [2, 3-d] pyrimidines as tumor targeted classical antifolates with selective uptake by folate receptor α and inhibition of de novo purine …
W Xiang, A Dekhne, A Doshi, C O'Connor, Z Hou, LH Matherly, A Gangjee
Bioorganic & medicinal chemistry 27 (23), 115125, 2019
22019
Discovery and structure-activity relationships (SAR) of a novel class of 2-substituted N-piperidinyl indole-based nociceptin opioid receptor ligands
ME Meyer, A Doshi, WE Polgar, NT Zaveri
Bioorganic & Medicinal Chemistry 92, 117421, 2023
2023
Targeted one-carbon (1C) metabolism inhibitors: Design, synthesis and biological evaluation of novel 5-substituted pyrrolo [3, 2-d] pyrimidines with pyridyl-and ortho …
A Doshi, A Wallace-Povirk, C O'Connor, Z Hou, L Matherly, A Gangjee
Cancer Research 80 (16_Supplement), 511-511, 2020
2020
Cellular pharmacodynamics of mitochondrial one-carbon metabolism-targeting 5-substituted pyrrolo[3,2-d]pyrimidine antifolates
A Dekhne, K Shah, GS Ducker, MJ Nayeen, JM Katinas, J Wong, A Doshi, ...
Cancer Research 79 (13_Supplement), 2992-2992, 2019
2019
Design and Synthesis of Pyrimidine Based Heterocycles as Potential Anti-cancer Agents with Combination Chemotherapeutic Potential or Targeted One Carbon Metabolism Inhibition …
A Doshi
Duquesne University, 2019
2019
Design, synthesis, and structure-activity relationships of pyrido [3, 2-d] pyrimidines as microtubule targeting agents that are effective against Pgp and beta III-tubulin …
A Gangjee, A Doshi, E Hamel, S Mooberry
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
Novel 5-substituted pyrrolo [2, 3-d] pyrimidines with pyridine glutamate side chain as selective folate receptors and proton-coupled folate transporter substrates: Potential …
A Gangjee, A Doshi, L Matherly, Z Hou, A Dekhne, C O'Connor, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017
2017
Correction to Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase
SM Deis, A Doshi, Z Hou, LH Matherly, A Gangjee, CE Dann III
Biochemistry 56 (7), 1025-1025, 2017
2017
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