Catalytic isonitrile insertions and condensations initiated by RNC–X complexation S Chakrabarty, S Choudhary, A Doshi, FQ Liu, R Mohan, MP Ravindra, ... Advanced synthesis & catalysis 356 (10), 2135-2196, 2014 | 139 | 2014 |
Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy AS Dekhne, K Shah, GS Ducker, JM Katinas, J Wong-Roushar, ... Molecular cancer therapeutics 18 (10), 1787-1799, 2019 | 46 | 2019 |
AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization A Bastian, S Matsuzaki, KM Humphries, GA Pharaoh, A Doshi, N Zaware, ... Cancer letters 388, 149-157, 2017 | 45 | 2017 |
Structural and enzymatic analysis of tumor-targeted antifolates that inhibit glycinamide ribonucleotide formyltransferase SM Deis, A Doshi, Z Hou, LH Matherly, A Gangjee, CE Dann III Biochemistry 55 (32), 4574-4582, 2016 | 26 | 2016 |
Design, Synthesis, and Biological Evaluation of 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines as Microtubule Targeting Agents F Islam, A Doshi, AJ Robles, TM Quadery, X Zhang, X Zhou, E Hamel, ... Molecules 27 (1), 321, 2022 | 5 | 2022 |
Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer S Choudhary, A Doshi, L Luckett-Chastain, M Ihnat, E Hamel, ... Bioorganic & medicinal chemistry 35, 116061, 2021 | 4 | 2021 |
Structure-based SAR in the design of selective or bifunctional nociceptin (NOP) receptor agonists ME Meyer, A Doshi, D Yasuda, NT Zaveri The AAPS Journal 23 (3), 68, 2021 | 2 | 2021 |
Discovery of amide-bridged pyrrolo [2, 3-d] pyrimidines as tumor targeted classical antifolates with selective uptake by folate receptor α and inhibition of de novo purine … W Xiang, A Dekhne, A Doshi, C O'Connor, Z Hou, LH Matherly, A Gangjee Bioorganic & medicinal chemistry 27 (23), 115125, 2019 | 2 | 2019 |
Discovery and structure-activity relationships (SAR) of a novel class of 2-substituted N-piperidinyl indole-based nociceptin opioid receptor ligands ME Meyer, A Doshi, WE Polgar, NT Zaveri Bioorganic & Medicinal Chemistry 92, 117421, 2023 | | 2023 |
Targeted one-carbon (1C) metabolism inhibitors: Design, synthesis and biological evaluation of novel 5-substituted pyrrolo [3, 2-d] pyrimidines with pyridyl-and ortho … A Doshi, A Wallace-Povirk, C O'Connor, Z Hou, L Matherly, A Gangjee Cancer Research 80 (16_Supplement), 511-511, 2020 | | 2020 |
Cellular pharmacodynamics of mitochondrial one-carbon metabolism-targeting 5-substituted pyrrolo[3,2-d]pyrimidine antifolates A Dekhne, K Shah, GS Ducker, MJ Nayeen, JM Katinas, J Wong, A Doshi, ... Cancer Research 79 (13_Supplement), 2992-2992, 2019 | | 2019 |
Design and Synthesis of Pyrimidine Based Heterocycles as Potential Anti-cancer Agents with Combination Chemotherapeutic Potential or Targeted One Carbon Metabolism Inhibition … A Doshi Duquesne University, 2019 | | 2019 |
Design, synthesis, and structure-activity relationships of pyrido [3, 2-d] pyrimidines as microtubule targeting agents that are effective against Pgp and beta III-tubulin … A Gangjee, A Doshi, E Hamel, S Mooberry ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Novel 5-substituted pyrrolo [2, 3-d] pyrimidines with pyridine glutamate side chain as selective folate receptors and proton-coupled folate transporter substrates: Potential … A Gangjee, A Doshi, L Matherly, Z Hou, A Dekhne, C O'Connor, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
Correction to Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase SM Deis, A Doshi, Z Hou, LH Matherly, A Gangjee, CE Dann III Biochemistry 56 (7), 1025-1025, 2017 | | 2017 |