Integration of GPCR signaling and sorting from very early endosomes via opposing APPL1 mechanisms S Sposini, FG Jean-Alphonse, MA Ayoub, A Oqua, C West, S Lavery, ... Cell reports 21 (10), 2855-2867, 2017 | 89 | 2017 |
AP2σ mutations impair calcium-sensing receptor trafficking and signaling, and show an endosomal pathway to spatially direct G-protein selectivity CM Gorvin, A Rogers, B Hastoy, AI Tarasov, M Frost, S Sposini, A Inoue, ... Cell reports 22 (4), 1054-1066, 2018 | 71 | 2018 |
NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95 B Compans, C Camus, E Kallergi, S Sposini, M Martineau, C Butler, ... Nature communications 12 (1), 1-18, 2021 | 69 | 2021 |
Functional recruitment of dynamin requires multimeric interactions for efficient endocytosis M Rosendale, TNN Van, D Grillo-Bosch, S Sposini, L Claverie, ... Nature communications 10 (1), 1-14, 2019 | 33 | 2019 |
Spatial encryption of G protein-coupled receptor signaling in endosomes; mechanisms and applications S Sposini, AC Hanyaloglu Biochemical pharmacology 143, 1-9, 2017 | 30 | 2017 |
Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G protein–coupled receptors M Baidya, P Kumari, H Dwivedi-Agnihotri, S Pandey, B Sokrat, S Sposini, ... Journal of Biological Chemistry, jbc. RA120. 013470, 2020 | 29 | 2020 |
Identification of transmembrane domains that regulate spatial arrangements and activity of prokineticin receptor 2 dimers S Sposini, G Caltabiano, AC Hanyaloglu, R Miele Molecular and cellular endocrinology 399, 362-372, 2015 | 27 | 2015 |
Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity D Azarnia Tehran, G Kochlamazashvili, NP Pampaloni, S Sposini, ... Science advances 8 (21), eabl5032, 2022 | 16 | 2022 |
Evolving view of membrane trafficking and signaling systems for g protein-coupled receptors S Sposini, AC Hanyaloglu Endocytosis and Signaling, 273-299, 2018 | 15 | 2018 |
Pharmacological programming of endosomal signaling activated by small molecule ligands of the follicle stimulating hormone receptor S Sposini, F De Pascali, R Richardson, NS Sayers, D Perrais, H Yu, ... Frontiers in Pharmacology 11, 1880, 2020 | 14 | 2020 |
Imaging endocytic vesicle formation at high spatial and temporal resolutions with the pulsed-pH protocol S Sposini, M Rosendale, L Claverie, TNN Van, D Jullié, D Perrais Nature Protocols 15 (9), 3088-3104, 2020 | 12 | 2020 |
Driving gonadotrophin hormone receptor signalling: the role of membrane trafficking S Sposini, AC Hanyaloglu Reproduction 156 (6), R195-R208, 2018 | 9 | 2018 |
Pharmacological characterization of low molecular weight biased agonists at the follicle stimulating hormone receptor F De Pascali, MA Ayoub, R Benevelli, S Sposini, J Lehoux, N Gallay, ... International journal of molecular sciences 22 (18), 9850, 2021 | 7 | 2021 |
Rational Engineering of an Improved Genetically Encoded pH Sensor Based on Superecliptic pHluorin Y Shen, Y Wen, S Sposini, AA Vishwanath, AS Abdelfattah, ER Schreiter, ... ACS sensors 8 (8), 3014-3022, 2023 | 3 | 2023 |
Confocal and TIRF microscopy based approaches to visualize arrestin trafficking in living cells FG Jean-Alphonse, S Sposini Methods in Cell Biology 166, 179-203, 2021 | 3 | 2021 |
Imaging of post-synaptic membrane trafficking in neuronal dendrites: progress, limitations, and new developments D Perrais, S Sposini, J Angibaud Neurophotonics 10 (4), 044404-044404, 2023 | 2 | 2023 |