| An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution EE Scott, YA He, MR Wester, MA White, CC Chin, JR Halpert, EF Johnson, ... Proceedings of the National Academy of Sciences 100 (23), 13196-13201, 2003 | 443 | 2003 |
| Mapping the pathways for O2 entry into and exit from myoglobin EE Scott, QH Gibson, JS Olson Journal of Biological Chemistry 276 (7), 5177-5188, 2001 | 402 | 2001 |
| Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl) imidazole at 1.9-Å resolution: insight into the range of P450 conformations and the coordination of … EE Scott, MA White, YA He, EF Johnson, CD Stout, JR Halpert Journal of Biological Chemistry 279 (26), 27294-27301, 2004 | 356 | 2004 |
| Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001 NM DeVore, EE Scott Nature 482 (7383), 116-119, 2012 | 351 | 2012 |
| Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism AA Walsh, GD Szklarz, EE Scott Journal of Biological Chemistry 288 (18), 12932-12943, 2013 | 295 | 2013 |
| Structures of human cytochrome P-450 2E1: insights into the binding of inhibitors and both small molecular weight and fatty acid substrates PR Porubsky, KM Meneely, EE Scott Journal of Biological Chemistry 283 (48), 33698-33707, 2008 | 274 | 2008 |
| Ligand migration in sperm whale myoglobin EE Scott, QH Gibson Biochemistry 36 (39), 11909-11917, 1997 | 179 | 1997 |
| A truncation of 2B subfamily cytochromes P450 yields increased expression levels, increased solubility, and decreased aggregation while retaining function EE Scott, M Spatzenegger, JR Halpert Archives of Biochemistry and Biophysics 395 (1), 57-68, 2001 | 153 | 2001 |
| Structures of cytochrome P450 3A4 EE Scott, JR Halpert Trends in biochemical sciences 30 (1), 5-7, 2005 | 145 | 2005 |
| Structure of the human lung cytochrome P450 2A13 BD Smith, JL Sanders, PR Porubsky, GH Lushington, CD Stout, EE Scott Journal of Biological Chemistry 282 (23), 17306-17313, 2007 | 121 | 2007 |
| Structures of human steroidogenic cytochrome P450 17A1 with substrates EM Petrunak, NM DeVore, PR Porubsky, EE Scott Journal of Biological Chemistry 289 (47), 32952-32964, 2014 | 118 | 2014 |
| Waterproofing the heme pocket: role of proximal amino acid side chains in preventing hemin loss from myoglobin EC Liong, Y Dou, EE Scott, JS Olson, GN Phillips Journal of Biological Chemistry 276 (12), 9093-9100, 2001 | 116 | 2001 |
| Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode PR Porubsky, KP Battaile, EE Scott Journal of biological chemistry 285 (29), 22282-22290, 2010 | 112 | 2010 |
| Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR DF Estrada, JS Laurence, EE Scott Journal of Biological Chemistry 288 (23), 17008-17018, 2013 | 102 | 2013 |
| Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes NM DeVore, EE Scott Journal of Biological Chemistry 287 (32), 26576-26585, 2012 | 88 | 2012 |
| Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine NM DeVore, KM Meneely, AG Bart, ES Stephens, KP Battaile, EE Scott The FEBS journal 279 (9), 1621-1631, 2012 | 79 | 2012 |
| A rational approach to re-engineer cytochrome P450 2B1 regioselectivity based on the crystal structure of cytochrome P450 2C5 S Kumar, EE Scott, H Liu, JR Halpert Journal of Biological Chemistry 278 (19), 17178-17184, 2003 | 76 | 2003 |
| Illuminating cytochrome P450 binding: Ru (ii)-caged inhibitors of CYP17A1 A Li, R Yadav, JK White, MK Herroon, BP Callahan, I Podgorski, C Turro, ... Chemical communications 53 (26), 3673-3676, 2017 | 74 | 2017 |
| Human Cytochrome P450 17A1 Conformational Selection: Modulation by ligand and cytochrome b5 DF Estrada, AL Skinner, JS Laurence, EE Scott Journal of Biological Chemistry 289 (20), 14310-14320, 2014 | 73 | 2014 |
| Possible pathway (s) of testosterone egress from the active site of cytochrome P450 2B1: a steered molecular dynamics simulation W Li, H Liu, EE Scott, F Gräter, JR Halpert, X Luo, J Shen, H Jiang Drug metabolism and disposition 33 (7), 910-919, 2005 | 62 | 2005 |
John S. OlsonRalph & Dorothy Looney Emeritus Professor, Department of BioSciences, RiceVerified email at rice.edu
