| 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ... Chemical science 4 (8), 3110-3117, 2013 | 176 | 2013 |
| Selectively targeting the kinome-conserved lysine of PI3Kδ as a general approach to covalent kinase inhibition SE Dalton, L Dittus, DA Thomas, MA Convery, J Nunes, JT Bush, ... Journal of the American Chemical Society 140 (3), 932-939, 2018 | 90 | 2018 |
| A cell‐permeable ester derivative of the JmjC histone demethylase inhibitor IOX1 R Schiller, G Scozzafava, A Tumber, JR Wickens, JT Bush, G Rai, ... ChemMedChem 9 (3), 566-571, 2014 | 75 | 2014 |
| Studies on deacetoxycephalosporin C synthase support a consensus mechanism for 2-oxoglutarate dependent oxygenases H Tarhonskaya, A Szöllössi, IKH Leung, JT Bush, L Henry, ... Biochemistry 53 (15), 2483-2493, 2014 | 51 | 2014 |
| A photoaffinity‐based fragment‐screening platform for efficient identification of protein ligands EK Grant, DJ Fallon, MM Hann, KGM Fantom, C Quinn, F Zappacosta, ... Angewandte Chemie 132 (47), 21282-21291, 2020 | 45 | 2020 |
| The Ugi four-component reaction enables expedient synthesis and comparison of photoaffinity probes JT Bush, LJ Walport, JF McGouran, IKH Leung, G Berridge, SS van Berkel, ... Chemical Science 4 (11), 4115-4120, 2013 | 41 | 2013 |
| A direct-to-biology high-throughput chemistry approach to reactive fragment screening RP Thomas, RE Heap, F Zappacosta, EK Grant, P Pogány, S Besley, ... Chemical science 12 (36), 12098-12106, 2021 | 32 | 2021 |
| A photoaffinity displacement assay and probes to study the cyclin‐dependent kinase family EK Grant, DJ Fallon, HC Eberl, KGM Fantom, F Zappacosta, C Messenger, ... Angewandte Chemie International Edition 58 (48), 17322-17327, 2019 | 32 | 2019 |
| Systematic review of clinical trials assessing the therapeutic efficacy of visceral leishmaniasis treatments: A first step to assess the feasibility of establishing an … JT Bush, M Wasunna, F Alves, J Alvar, PL Olliaro, M Otieno, CH Sibley, ... PLoS neglected tropical diseases 11 (9), e0005781, 2017 | 30 | 2017 |
| Profiling sulfur (VI) fluorides as reactive functionalities for chemical biology tools and expansion of the ligandable proteome KE Gilbert, A Vuorinen, A Aatkar, P Pogány, J Pettinger, EK Grant, ... ACS chemical biology 18 (2), 285-295, 2023 | 28 | 2023 |
| Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase A Cioce, G Bineva-Todd, AJ Agbay, J Choi, TM Wood, MF Debets, ... ACS chemical biology 16 (10), 1961-1967, 2021 | 27 | 2021 |
| A turing test for molecular generators JT Bush, P Pogany, SD Pickett, M Barker, A Baxter, S Campos, ... Journal of Medicinal Chemistry 63 (20), 11964-11971, 2020 | 26 | 2020 |
| 1, 3, 5-Trisubstituted benzenes as fluorescent photoaffinity probes for human carbonic anhydrase II capture PS Addy, B Saha, NDP Singh, AK Das, JT Bush, C Lejeune, CJ Schofield, ... Chemical communications 49 (19), 1930-1932, 2013 | 25 | 2013 |
| Efficient ligand discovery using sulfur (VI) fluoride reactive fragments A Aatkar, A Vuorinen, OE Longfield, K Gilbert, R Peltier-Heap, CD Wagner, ... ACS Chemical Biology 18 (9), 1926-1937, 2023 | 12 | 2023 |
| Quantitative MS‐Based Proteomics: Comparing the MCF‐7 Cellular Response to Hypoxia and a 2‐Oxoglutarate Analogue JT Bush, MC Chan, S Mohammed, CJ Schofield ChemBioChem 21 (11), 1647-1655, 2020 | 8 | 2020 |
| YcfDRM is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase R Sekirnik, SE Wilkins, J Bush, H Tarhonskaya, M Münzel, A Hussein, ... Extremophiles 22, 553-562, 2018 | 7 | 2018 |
| One‐Step synthesis of photoaffinity probes for live‐cell MS‐based proteomics DJ Fallon, S Lehmann, C Chung, A Phillipou, C Eberl, KGM Fantom, ... Chemistry–A European Journal 27 (71), 17880-17888, 2021 | 6 | 2021 |
| Small-molecules that covalently react with a human prolyl hydroxylase–towards activity modulation and substrate capture JT Bush, RK Leśniak, TL Yeh, R Belle, H Kramer, A Tumber, ... Chemical communications 55 (8), 1020-1023, 2019 | 6 | 2019 |
| A chemoproteomic platform for selective deubiquitinase inhibitor discovery R Cookson, A Vuorinen, J Pettinger, CR Kennedy, JM Kirkpatrick, ... Cell Reports Physical Science 4 (10), 2023 | 4 | 2023 |
| Automated LC-MS analysis and data extraction for high-throughput chemistry J Mason, H Wilders, DJ Fallon, RP Thomas, JT Bush, NCO Tomkinson, ... Digital Discovery 2 (6), 1894-1899, 2023 | 4 | 2023 |
