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Xinmei Wen
Xinmei Wen
Thomas Jefferson University, Xuanwu Hospital, Capital Medical University
Verified email at jefferson.edu
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Cited by
Cited by
Year
Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death
X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ...
Neuron 84 (6), 1213-1225, 2014
5562014
Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death
X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ...
Neuron 84 (6), 1213-1225, 2014
5562014
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons
Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ...
Nature medicine 24 (3), 313-325, 2018
5392018
Cell-to-cell transmission of dipeptide repeat proteins linked to C9orf72-ALS/FTD
T Westergard, BK Jensen, X Wen, J Cai, E Kropf, L Iacovitti, P Pasinelli, ...
Cell reports 17 (3), 645-652, 2016
2182016
Repeat‐associated non‐AUG translation in C9orf72‐ALS/FTD is driven by neuronal excitation and stress
T Westergard, K McAvoy, K Russell, X Wen, Y Pang, B Morris, P Pasinelli, ...
EMBO molecular medicine 11 (2), e9423, 2019
1102019
Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene
X Wen, T Westergard, P Pasinelli, D Trotti
Neuroscience letters 636, 16-26, 2017
482017
Synaptic dysfunction induced by glycine‐alanine dipeptides in C9orf72‐ALS/FTD is rescued by SV 2 replenishment
BK Jensen, MH Schuldi, K McAvoy, KA Russell, A Boehringer, BM Curran, ...
EMBO molecular medicine 12 (5), e10722, 2020
462020
A mouse model with widespread expression of the C9orf72-linked glycine–arginine dipeptide displays non-lethal ALS/FTD-like phenotypes
BM Verdone, ME Cicardi, X Wen, S Sriramoji, K Russell, SS Markandaiah, ...
Scientific Reports 12 (1), 5644, 2022
122022
Cell-to-cell transmission of dipeptide repeat proteins linked to C9orf72-ALS/FTD. Cell Rep 17: 645–652
T Westergard, BK Jensen, X Wen, J Cai, E Kropf, L Iacovitti, P Pasinelli, ...
122016
Antisense proline-arginine RAN dipeptides linked to
X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ...
C9ORF72, 0
10
Aberrant expression of the axon guidance cue netrin-1 by SOD1-ALS astrocytes contributes to motor neuron degeneration.
K Krishnamurthy, S Markandaiah, M Cicardi, B Ghosh, X Wen, K McAvoy, ...
GLIA 69, E194-E194, 2021
2021
Identification of Pathogenic Determinants and Mechanisms of C9ORF72 linked ALS/FTD
X Wen
Thomas Jefferson University, 2016
2016
Aberrant secretion of netrin-1 from astrocytes is toxic to motor neurons in a mouse model of amyotrophic lateral sclerosis
A Bogush, E Foran, X Wen, L Rosenblum, A Kia, W Tan, P Pasinelli, ...
Implication of a sumoylated c-terminal fragment of the astroglial glutamate …, 2013
2013
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T Westergard, BK Jensen, X Wen, J Cai
Cell 10, 11-2016, 0
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