| Overexpression of the MTA1 gene in gastrointestinal carcinomas: Correlation with invasion and metastasis Y Toh, E Oki, S Oda, E Tokunaga, S Ohno, Y Maehara, GL Nicolson, ... International Journal of Cancer 74 (4), 459-463, 1997 | 286 | 1997 |
| Deregulation of the Akt pathway in human cancer E Tokunaga, E Oki, A Egashira, N Sadanaga, M Morita, Y Kakeji, ... Current cancer drug targets 8 (1), 27-36, 2008 | 285 | 2008 |
| Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies Y Nakamura, H Taniguchi, M Ikeda, H Bando, K Kato, C Morizane, T Esaki, ... Nature medicine 26 (12), 1859-1864, 2020 | 264 | 2020 |
| Prognostic nutritional index predicts severe complications, recurrence, and poor prognosis in patients with colorectal cancer undergoing primary tumor resection R Tokunaga, Y Sakamoto, S Nakagawa, Y Miyamoto, N Yoshida, E Oki, ... Diseases of the Colon & Rectum 58 (11), 1048-1057, 2015 | 254 | 2015 |
| Activation of PI3K/Akt signaling and hormone resistance in breast cancer E Tokunaga, Y Kimura, K Mashino, E Oki, A Kataoka, S Ohno, M Morita, ... Breast cancer 13, 137-144, 2006 | 250 | 2006 |
| Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition GS Wong, J Zhou, JB Liu, Z Wu, X Xu, T Li, D Xu, SE Schumacher, ... Nature medicine 24 (7), 968-977, 2018 | 235 | 2018 |
| Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer E Oki, H Baba, E Tokunaga, T Nakamura, N Ueda, M Futatsugi, ... International journal of cancer 117 (3), 376-380, 2005 | 229 | 2005 |
| Akt is frequently activated in HER2/neu‐positive breast cancers and associated with poor prognosis among hormone‐treated patients E Tokunaga, Y Kimura, E Oki, N Ueda, M Futatsugi, K Mashino, ... International journal of cancer 118 (2), 284-289, 2006 | 217 | 2006 |
| Activation of transforming growth factor beta 1 signaling in gastric cancer-associated fibroblasts increases their motility, via expression of rhomboid 5 homolog 2, and ability … T Ishimoto, K Miyake, T Nandi, M Yashiro, N Onishi, KK Huang, SJ Lin, ... Gastroenterology 153 (1), 191-204. e16, 2017 | 197 | 2017 |
| Clinical significance of heparin-binding epidermal growth factor–like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer Y Tanaka, S Miyamoto, SO Suzuki, E Oki, H Yagi, K Sonoda, A Yamazaki, ... Clinical Cancer Research 11 (13), 4783-4792, 2005 | 193 | 2005 |
| Advances in esophageal cancer surgery in Japan: an analysis of 1000 consecutive patients treated at a single institute M Morita, R Yoshida, K Ikeda, A Egashira, E Oki, N Sadanaga, Y Kakeji, ... Surgery 143 (4), 499-508, 2008 | 192 | 2008 |
| Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: molecular mechanisms of carcinogenesis Y Toh, E Oki, K Ohgaki, Y Sakamoto, S Ito, A Egashira, H Saeki, Y Kakeji, ... International journal of clinical oncology 15, 135-144, 2010 | 189 | 2010 |
| Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six randomised … T André, J Meyerhardt, T Iveson, A Sobrero, T Yoshino, I Souglakos, ... The lancet oncology 21 (12), 1620-1629, 2020 | 185 | 2020 |
| Assessment of sarcopenia as a predictor of poor outcomes after esophagectomy in elderly patients with esophageal cancer Y Nakashima, H Saeki, R Nakanishi, M Sugiyama, J Kurashige, E Oki, ... Annals of surgery 267 (6), 1100-1104, 2018 | 175 | 2018 |
| Integrated multiregional analysis proposing a new model of colorectal cancer evolution R Uchi, Y Takahashi, A Niida, T Shimamura, H Hirata, K Sugimachi, ... PLoS genetics 12 (2), e1005778, 2016 | 170 | 2016 |
| Validation of HB-EGF and amphiregulin as targets for human cancer therapy F Yotsumoto, H Yagi, SO Suzuki, E Oki, H Tsujioka, T Hachisuga, ... Biochemical and biophysical research communications 365 (3), 555-561, 2008 | 163 | 2008 |
| Sarcopenia is an independent predictor of complications after colorectal cancer surgery R Nakanishi, E Oki, S Sasaki, K Hirose, T Jogo, K Edahiro, S Korehisa, ... Surgery today 48, 151-157, 2018 | 158 | 2018 |
| The association between Akt activation and resistance to hormone therapy in metastatic breast cancer E Tokunaga, A Kataoka, Y Kimura, E Oki, K Mashino, K Nishida, T Koga, ... European Journal of Cancer 42 (5), 629-635, 2006 | 157 | 2006 |
| An imbalance in TAZ and YAP expression in hepatocellular carcinoma confers cancer stem cell–like behaviors contributing to disease progression H Hayashi, T Higashi, N Yokoyama, T Kaida, K Sakamoto, Y Fukushima, ... Cancer research 75 (22), 4985-4997, 2015 | 147 | 2015 |
| Reduced expression of p33ING1 and the relationship with p53 expression in human gastric cancer E Oki, Y Maehara, E Tokunaga, Y Kakeji, K Sugimachi Cancer letters 147 (1-2), 157-162, 1999 | 146 | 1999 |
