| Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation CM Olson, B Jiang, MA Erb, Y Liang, ZM Doctor, Z Zhang, T Zhang, ... Nature chemical biology 14 (2), 163-170, 2018 | 430 | 2018 |
| Development of dual and selective degraders of cyclin‐dependent kinases 4 and 6 B Jiang, ES Wang, KA Donovan, Y Liang, ES Fischer, T Zhang, NS Gray Angewandte Chemie International Edition 58 (19), 6321-6326, 2019 | 206 | 2019 |
| Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML M Brand, B Jiang, S Bauer, KA Donovan, Y Liang, ES Wang, RP Nowak, ... Cell chemical biology 26 (2), 300-306. e9, 2019 | 202 | 2019 |
| Mapping the degradable kinome provides a resource for expedited degrader development KA Donovan, FM Ferguson, JW Bushman, NA Eleuteri, D Bhunia, SS Ryu, ... Cell 183 (6), 1714-1731. e10, 2020 | 172 | 2020 |
| MELK is not necessary for the proliferation of basal-like breast cancer cells HT Huang, HS Seo, T Zhang, Y Wang, B Jiang, Q Li, DL Buckley, B Nabet, ... Elife 6, e26693, 2017 | 103 | 2017 |
| Ligase IV inhibitor SCR7 enhances gene editing directed by CRISPR–Cas9 and ssODN in human cancer cells Z Hu, Z Shi, X Guo, B Jiang, G Wang, D Luo, Y Chen, YS Zhu Cell & bioscience 8, 1-15, 2018 | 97 | 2018 |
| INK4 tumor suppressor proteins mediate resistance to CDK4/6 kinase inhibitors Q Li, B Jiang, J Guo, H Shao, IS Del Priore, Q Chang, R Kudo, Z Li, ... Cancer discovery 12 (2), 356-371, 2022 | 83 | 2022 |
| Discovery and resistance mechanism of a selective CDK12 degrader B Jiang, Y Gao, J Che, W Lu, IH Kaltheuner, R Dries, M Kalocsay, ... Nature chemical biology 17 (6), 675-683, 2021 | 80 | 2021 |
| ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer J Deng, A Thennavan, I Dolgalev, T Chen, J Li, A Marzio, JT Poirier, ... Nature cancer 2 (5), 503-514, 2021 | 76 | 2021 |
| A chemoproteomic strategy for direct and proteome-wide covalent inhibitor target-site identification CM Browne, B Jiang, SB Ficarro, ZM Doctor, JL Johnson, JD Card, ... Journal of the American Chemical Society 141 (1), 191-203, 2018 | 72 | 2018 |
| Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells L Johannessen, TB Sundberg, DJ O'Connell, R Kolde, J Berstler, ... Nature chemical biology 13 (10), 1102-1108, 2017 | 56 | 2017 |
| USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy W Xiong, X Gao, T Zhang, B Jiang, MM Hu, X Bu, Y Gao, LZ Zhang, ... Nature communications 13 (1), 1700, 2022 | 53 | 2022 |
| Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition A Fassl, C Brain, M Abu-Remaileh, I Stukan, D Butter, P Stepien, AS Feit, ... Science advances 6 (25), eabb2210, 2020 | 50 | 2020 |
| Targeting the PI5P4K lipid kinase family in cancer using covalent inhibitors SC Sivakumaren, H Shim, T Zhang, FM Ferguson, MR Lundquist, ... Cell chemical biology 27 (5), 525-537. e6, 2020 | 35 | 2020 |
| Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma B Jiang, J Jiang, IH Kaltheuner, AB Iniguez, K Anand, FM Ferguson, ... European Journal of Medicinal Chemistry 221, 113481, 2021 | 30 | 2021 |
| Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia X Gao, S Qin, Y Wu, C Chu, B Jiang, RH Johnson, D Kuang, J Zhang, ... The Journal of clinical investigation 131 (16), 2021 | 28 | 2021 |
| ELISA detection of semicarbazide based on a fast sample pretreatment method Z Fang, B Jiang, W Wu, Z Xiang, C Ouyang, T Huang, J Chen, L Zeng Chemical communications 49 (55), 6164-6166, 2013 | 28 | 2013 |
| Facile synthesis of 2-bromoindoles by ligand-free CuI-catalyzed intramolecular cross-coupling of gem-dibromoolefins B Jiang, K Tao, W Shen, J Zhang Tetrahedron Letters 51 (48), 6342-6344, 2010 | 28 | 2010 |
| Harmine induces adipocyte thermogenesis through RAC1-MEK-ERK-CHD4 Axis T Nie, X Hui, L Mao, B Nie, K Li, W Sun, X Gao, X Tang, Y Xu, B Jiang, ... Scientific reports 6 (1), 36382, 2016 | 27 | 2016 |
| Facile synthesis of 2-amino-3-bromoquinolines by palladium-catalyzed isocyanide insertion and cyclization of gem-dibromovinylanilines B Jiang, L Hu, W Gui RSC Advances 4 (27), 13850-13853, 2014 | 19 | 2014 |
Georg E WinterPrincipal Investigator at CeMM, ViennaVerified email at cemm.oeaw.ac.at
