| Amino acid derivatives as bitter taste receptor (T2R) blockers SP Pydi, T Sobotkiewicz, R Billakanti, RP Bhullar, MC Loewen, ... Journal of Biological Chemistry 289 (36), 25054-25066, 2014 | 100 | 2014 |
| Bitter taste receptor T2R1 is activated by dipeptides and tripeptides J Upadhyaya, SP Pydi, N Singh, RE Aluko, P Chelikani Biochemical and biophysical research communications 398 (2), 331-335, 2010 | 95 | 2010 |
| Structural basis of activation of bitter taste receptor T2R1 and comparison with Class A G-protein-coupled receptors (GPCRs) N Singh, SP Pydi, J Upadhyaya, P Chelikani Journal of Biological Chemistry 286 (41), 36032-36041, 2011 | 85 | 2011 |
| Abscisic acid acts as a blocker of the bitter taste G protein-coupled receptor T2R4 SP Pydi, A Jaggupilli, KM Nelson, SR Abrams, RP Bhullar, MC Loewen, ... Biochemistry 54 (16), 2622-2631, 2015 | 53 | 2015 |
| Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis SP Pydi, S Jain, W Tung, Y Cui, L Zhu, W Sakamoto, S Jain, BS Abel, ... Nature Communications 10 (1), 2936, 2019 | 50 | 2019 |
| The third intracellular loop plays a critical role in bitter taste receptor activation SP Pydi, N Singh, J Upadhyaya, RP Bhullar, P Chelikani Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (1), 231-236, 2014 | 45 | 2014 |
| Characterization of the direct interaction between hybrid sensor kinases PA1611 and RetS that controls biofilm formation and the type III secretion system in Pseudomonas aeruginosa AY Bhagirath, SP Pydi, Y Li, C Lin, W Kong, P Chelikani, K Duan ACS infectious diseases 3 (2), 162-175, 2017 | 43 | 2017 |
| Dextromethorphan mediated bitter taste receptor activation in the pulmonary circuit causes vasoconstriction JD Upadhyaya, N Singh, AS Sikarwar, R Chakraborty, SP Pydi, ... PLoS One 9 (10), e110373, 2014 | 41 | 2014 |
| Constitutively active mutant gives novel insights into the mechanism of bitter taste receptor activation SP Pydi, RP Bhullar, P Chelikani Journal of neurochemistry 122 (3), 537-544, 2012 | 40 | 2012 |
| Lack of adipocyte purinergic P2Y6 receptor greatly improves whole body glucose homeostasis S Jain, SP Pydi, KS Toti, B Robaye, M Idzko, O Gavrilova, J Wess, ... Proceedings of the National Academy of Sciences 117 (48), 30763-30774, 2020 | 39 | 2020 |
| Hepatic Gi signaling regulates whole-body glucose homeostasis M Rossi, L Zhu, SM McMillin, SP Pydi, S Jain, L Wang, Y Cui, RJ Lee, ... The Journal of clinical investigation 128 (2), 746-759, 2018 | 35 | 2018 |
| Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity L Wang, SP Pydi, L Zhu, LF Barella, Y Cui, O Gavrilova, KK Bence, ... Nature Communications 11 (1), 2995, 2020 | 34 | 2020 |
| Recent advances in structure and function studies on human bitter taste receptors S Prasad Pydi, J Upadhyaya, N Singh, R Pal Bhullar, P Chelikani Current Protein and Peptide Science 13 (6), 501-508, 2012 | 34 | 2012 |
| Selective activation of Gs signaling in adipocytes causes striking metabolic improvements in mice L Wang, SP Pydi, Y Cui, L Zhu, J Meister, O Gavrilova, R Berdeaux, ... Molecular Metabolism 27, 83-91, 2019 | 32 | 2019 |
| Metabolic roles of G protein‐coupled receptor signaling in obesity and type 2 diabetes LF Barella, S Jain, T Kimura, SP Pydi The FEBS journal 288 (8), 2622-2644, 2021 | 31 | 2021 |
| Cholesterol modulates bitter taste receptor function SP Pydi, M Jafurulla, L Wai, RP Bhullar, P Chelikani, A Chattopadhyay Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (9), 2081-2087, 2016 | 31 | 2016 |
| New insights into structural determinants for prostanoid thromboxane A2 receptor-and prostacyclin receptor-G protein coupling R Chakraborty, SP Pydi, S Gleim, RP Bhullar, J Hwa, S Dakshinamurti, ... Molecular and cellular biology, 2013 | 31 | 2013 |
| Metabolic functions of G protein-coupled receptors in hepatocytes—Potential applications for diabetes and NAFLD T Kimura, SP Pydi, J Pham, N Tanaka Biomolecules 10 (10), 1445, 2020 | 30 | 2020 |
| Serum thrombospondin 2 is a novel predictor for the severity in the patients with NAFLD T Kimura, N Tanaka, N Fujimori, T Yamazaki, T Katsuyama, Y Iwashita, ... Liver International 41 (3), 505-514, 2021 | 29 | 2021 |
| Use of DREADD technology to identify novel targets for antidiabetic drugs L Wang, L Zhu, J Meister, DBJ Bone, SP Pydi, M Rossi, J Wess Annual review of pharmacology and toxicology 61, 421-440, 2021 | 28 | 2021 |
Jurgen WessNIH-NIDDKVerified email at niddk.nih.gov
