| A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ... Nature neuroscience 20 (8), 1052-1061, 2017 | 344 | 2017 |
| Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture Q Zhang, J Sidorenko, B Couvy-Duchesne, RE Marioni, MJ Wright, ... Nature communications 11 (1), 4799, 2020 | 335 | 2020 |
| Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation JC Bis, X Jian, BW Kunkle, Y Chen, KL Hamilton-Nelson, WS Bush, ... Molecular psychiatry 25 (8), 1859-1875, 2020 | 235 | 2020 |
| SynGAP regulates steady-state and activity-dependent phosphorylation of cofilin HJ Carlisle, P Manzerra, E Marcora, MB Kennedy Journal of Neuroscience 28 (50), 13673-13683, 2008 | 149 | 2008 |
| Cholesterol and matrisome pathways dysregulated in astrocytes and microglia TCW Julia, L Qian, NH Pipalia, MJ Chao, SA Liang, Y Shi, BR Jain, ... Cell 185 (13), 2213-2233. e25, 2022 | 147 | 2022 |
| Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes G Novikova, M Kapoor, J Tcw, EM Abud, AG Efthymiou, SX Chen, ... Nature communications 12 (1), 1610, 2021 | 143 | 2021 |
| The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding A Sharma, M Moore, E Marcora, JE Lee, Y Qiu, S Samaras, R Stein Molecular and cellular biology 19 (1), 704-713, 1999 | 130 | 1999 |
| Microglial phagocytosis: a disease-associated process emerging from Alzheimer’s disease genetics A Podleśny-Drabiniok, E Marcora, AM Goate Trends in Neurosciences 43 (12), 965-979, 2020 | 120 | 2020 |
| Stimulation of NeuroD activity by huntingtin and huntingtin-associated proteins HAP1 and MLK2 E Marcora, K Gowan, JE Lee Proceedings of the National Academy of Sciences 100 (16), 9578-9583, 2003 | 119 | 2003 |
| The variant call format provides efficient and robust storage of GWAS summary statistics MS Lyon, SJ Andrews, B Elsworth, TR Gaunt, G Hemani, E Marcora Genome biology 22 (1), 32, 2021 | 117 | 2021 |
| Molecular basis for the loss-of-function effects of the Alzheimer's disease–associated R47H variant of the immune receptor TREM2 A Sudom, S Talreja, J Danao, E Bragg, R Kegel, X Min, J Richardson, ... Journal of Biological Chemistry 293 (32), 12634-12646, 2018 | 103 | 2018 |
| The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus E Marcora, MB Kennedy Human molecular genetics 19 (22), 4373-4384, 2010 | 99 | 2010 |
| NeuroD1 in the endocrine pancreas: localization and dual function as an activator and repressor P Itkin‐Ansari, E Marcora, I Geron, B Tyrberg, C Demeterco, E Hao, ... Developmental dynamics: an official publication of the American Association …, 2005 | 95 | 2005 |
| Causal associations between modifiable risk factors and the Alzheimer's phenome SJ Andrews, B Fulton‐Howard, P O'Reilly, E Marcora, AM Goate, ... Annals of neurology 89 (1), 54-65, 2021 | 94 | 2021 |
| N-(4-hydroxyphenyl) retinamide: a potent inducer of apoptosis in human neuroblastoma cells A Mariotti, E Marcora, G Bunone, A Costa, U Veronesi, MA Pierotti, ... Oxford University Press, 1994 | 81 | 1994 |
| A tale of two genes: microglial Apoe and Trem2 AA Pimenova, E Marcora, AM Goate Immunity 47 (3), 398-400, 2017 | 56 | 2017 |
| Alzheimer's-associated PU. 1 expression levels regulate microglial inflammatory response AA Pimenova, M Herbinet, I Gupta, SI Machlovi, KR Bowles, E Marcora, ... Neurobiology of disease 148, 105217, 2021 | 55 | 2021 |
| The complex genetic architecture of Alzheimer's disease: novel insights and future directions SJ Andrews, AE Renton, B Fulton-Howard, A Podlesny-Drabiniok, ... EBioMedicine 90, 2023 | 53 | 2023 |
| Cholesterol and matrisome pathways dysregulated in human APOE ε4 glia J Tcw, SA Liang, L Qian, NH Pipalia, MJ Chao, Y Shi, SE Bertelsen, ... BioRxiv, 713362, 2019 | 43 | 2019 |
| Microglial efferocytosis: diving into the Alzheimer’s disease gene pool C Romero-Molina, F Garretti, SJ Andrews, E Marcora, AM Goate Neuron 110 (21), 3513-3533, 2022 | 40 | 2022 |
Alison GoateProfessor of Genetics & Genomic Sciences, Icahn School of Medicine at Mount SinaiVerified email at mssm.edu
