A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity JB Bramsen, MB Laursen, AF Nielsen, TB Hansen, C Bus, N Langkjær, ... Nucleic acids research 37 (9), 2867-2881, 2009 | 431 | 2009 |
About mechanism of chitosan cross-linking with glutaraldehyde NR Kildeeva, PA Perminov, LV Vladimirov, VV Novikov, SN Mikhailov Russian journal of bioorganic chemistry 35, 360-369, 2009 | 253* | 2009 |
Bisphosphonate conjugates and methods of making and using the same N Padioukova, S Mikhailov, HBF Dixon, G Tzeitline US Patent 6,750,340, 2004 | 70* | 2004 |
Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue GG Reinholz, B Getz, ES Sanders, MY Karpeisky, NS Padyukova, ... Breast cancer research and treatment 71, 257-268, 2002 | 66 | 2002 |
An Efficient Synthesis and Physico-Chemical Properties OF 2′-O-d-Ribofuranosylnuleosides, Minor tRNA Components SN Mikhailov, EV Efimtseva, GV Gurskaya, MV Fomitcheva, SV Meshkov, ... Journal of carbohydrate chemistry 16 (1), 75-92, 1997 | 56 | 1997 |
Periodate oxidation in chemistry of nucleic acids: Dialdehyde derivatives of nucleosides, nucleotides, and oligonucleotides BS Ermolinsky, SN Mikhailov Russian Journal of Bioorganic Chemistry 26, 429-449, 2000 | 53 | 2000 |
New syntheses of 2′-C-methylnucleosides starting from D-glucose and D-ribose LN Beigelman, BS Ermolinsky, GV Gurskaya, EN Tsapkina, MY Karpeisky, ... Carbohydrate research 166 (2), 219-232, 1987 | 53 | 1987 |
Synthesis and properties of 3′-C-methylnucleosides and their phosphoric esters SN Mikhailov, LN Beigelman, GV Gurskaya, NS Padyukova, GI Yakovlev, ... Carbohydrate Research 124 (1), 75-96, 1983 | 52 | 1983 |
Phosphoramidite building blocks for efficient incorporation of 2′-O-aminoethoxy (and propoxy) methyl nucleosides into oligonucleotides GV Bobkov, SN Mikhailov, A Van Aerschot, P Herdewijn Tetrahedron 64 (27), 6238-6251, 2008 | 50 | 2008 |
Antiviral and antimicrobial nucleoside derivatives: structural features and mechanisms of action AA Zenchenko, MS Drenichev, IA Il’Icheva, SN Mikhailov Molecular biology 55, 786-812, 2021 | 49 | 2021 |
Cytokinin nucleosides-natural compounds with a unique spectrum of biological activities M S Drenichev, V E Oslovsky, S N Mikhailov Current topics in medicinal chemistry 16 (23), 2562-2576, 2016 | 49 | 2016 |
Hydrolysis of 2'-and 3'-C-methyluridine 2', 3'-cyclic monophosphates and interconversion and dephosphorylation of the resulting 2'-and 3'-monophosphates: comparison with the … SN Mikhailov, M Oivanen, P Oksman, H Lonnberg The Journal of Organic Chemistry 57 (15), 4122-4126, 1992 | 49 | 1992 |
Branched-chain sugar nucleosides. Synthesis of 3′-C-ethyl (and 3′-C-butyl) uridine A Rosenthal, SN Mikhailov Carbohydrate Research 79 (2), 235-242, 1980 | 49 | 1980 |
Chemical incorporation of 1-methyladenosine into oligonucleotides SN Mikhailov, J Rozenski, EV Efimtseva, R Busson, A Van Aerschot, ... Nucleic acids research 30 (5), 1124-1131, 2002 | 47 | 2002 |
Solid-Supported 2′-O-Glycoconjugation of Oligonucleotides by Azidation and Click Reactions A Kiviniemi, P Virta, MS Drenichev, SN Mikhailov, H Lonnberg Bioconjugate Chemistry 22 (6), 1249-1255, 2011 | 44 | 2011 |
Synthesis of 2′-O-α-d-ribofuranosyladenosine, monomeric unit of poly (ADP–ribose) SN Mikhailov, IV Kulikova, K Nauwelaerts, P Herdewijn Tetrahedron 64 (12), 2871-2876, 2008 | 43 | 2008 |
Disaccharide nucleosides and their incorporation into oligonucleotides EV Efimtseva, IV Kulikova, SN Mikhailov Current Organic Chemistry 11 (4), 337-354, 2007 | 43 | 2007 |
Modification of the length and structure of the linker of N6-benzyladenosine modulates its selective antiviral activity against enterovirus 71 MS Drenichev, VE Oslovsky, L Sun, A Tijsma, NN Kurochkin, VI Tararov, ... European Journal of Medicinal Chemistry 111, 84-94, 2016 | 40 | 2016 |
Crosslinking of chitosan with dialdehyde derivatives of nucleosides and nucleotides. Mechanism and comparison with glutaraldehyde SN Mikhailov, AN Zakharova, MS Drenichev, AV Ershov, MA Kasatkina, ... Nucleosides, nucleotides and nucleic acids 35 (3), 114-129, 2016 | 40 | 2016 |
Chemical modification of the plant isoprenoid cytokinin N6-isopentenyladenosine yields a selective inhibitor of human enterovirus 71 replication VI Tararov, A Tijsma, SV Kolyachkina, VE Oslovsky, J Neyts, ... European Journal of Medicinal Chemistry 90, 406-413, 2015 | 40 | 2015 |