| Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes L Alamo, JS Ware, A Pinto, RE Gillilan, JG Seidman, CE Seidman, ... elife 6, e24634, 2017 | 182 | 2017 |
| Three-dimensional reconstruction of tarantula myosin filaments suggests how phosphorylation may regulate myosin activity L Alamo, W Wriggers, A Pinto, F Bártoli, L Salazar, FQ Zhao, R Craig, ... Journal of molecular biology 384 (4), 780-797, 2008 | 173 | 2008 |
| Conserved intramolecular interactions maintain myosin interacting-heads motifs explaining tarantula muscle super-relaxed state structural basis L Alamo, D Qi, W Wriggers, A Pinto, J Zhu, A Bilbao, RE Gillilan, S Hu, ... Journal of molecular biology 428 (6), 1142-1164, 2016 | 101 | 2016 |
| Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals KH Lee, G Sulbarán, S Yang, JY Mun, L Alamo, A Pinto, O Sato, M Ikebe, ... Proceedings of the National Academy of Sciences 115 (9), E1991-E2000, 2018 | 85 | 2018 |
| Role of von Willebrand factor in vascular disease P Paulinska, A Spiel, B Jilma Hämostaseologie 29 (01), 32-38, 2009 | 81 | 2009 |
| A molecular model of phosphorylation-based activation and potentiation of tarantula muscle thick filaments R Brito, L Alamo, U Lundberg, JR Guerrero, A Pinto, G Sulbarán, ... Journal of molecular biology 414 (1), 44-61, 2011 | 76 | 2011 |
| An invertebrate smooth muscle with striated muscle myosin filaments G Sulbarán, L Alamo, A Pinto, G Márquez, F Méndez, R Padrón, R Craig Proceedings of the National Academy of Sciences 112 (42), E5660-E5668, 2015 | 52 | 2015 |
| An invertebrate smooth muscle with striated muscle myosin filaments G Sulbarán, L Alamo, A Pinto, G Márquez, F Méndez, R Padrón, R Craig Proceedings of the National Academy of Sciences 112 (42), E5660-E5668, 2015 | 52 | 2015 |
| Lessons from a tarantula: new insights into myosin interacting-heads motif evolution and its implications on disease L Alamo, A Pinto, G Sulbarán, J Mavárez, R Padrón Biophysical Reviews 10, 1465-1477, 2018 | 43 | 2018 |
| The myosin interacting-heads motif is present in the relaxed thick filament of the striated muscle of scorpion A Pinto, F Sánchez, L Alamo, R Padrón Journal of structural biology 180 (3), 469-478, 2012 | 42 | 2012 |
| Lessons from a tarantula: new insights into muscle thick filament and myosin interacting-heads motif structure and function L Alamo, N Koubassova, A Pinto, R Gillilan, A Tsaturyan, R Padrón Biophysical Reviews 9, 461-480, 2017 | 37 | 2017 |
| The myosin interacting-heads motif present in live tarantula muscle explains tetanic and posttetanic phosphorylation mechanisms R Padrón, W Ma, S Duno-Miranda, N Koubassova, KH Lee, A Pinto, ... Proceedings of the National Academy of Sciences 117 (22), 11865-11874, 2020 | 33 | 2020 |
| Different head environments in tarantula thick filaments support a cooperative activation process G Sulbarán, A Biasutto, L Alamo, C Riggs, A Pinto, F Méndez, R Craig, ... Biophysical journal 105 (9), 2114-2122, 2013 | 27 | 2013 |
| Tarantula myosin free head regulatory light chain phosphorylation stiffens N-terminal extension, releasing it and blocking its docking back L Alamo, XE Li, LM Espinoza-Fonseca, A Pinto, DD Thomas, W Lehman, ... Molecular bioSystems 11 (8), 2180-2189, 2015 | 22 | 2015 |
| Sequential myosin phosphorylation activates tarantula thick filament via a disorder–order transition LM Espinoza-Fonseca, L Alamo, A Pinto, DD Thomas, R Padrón Molecular bioSystems 11 (8), 2167-2179, 2015 | 16 | 2015 |
| Hyperhomocystinemia and 677C T methylenetetrahydrofolate reductase polymorphism as a cardiovascular risk factor in childhood CM Cid, NG Giralt, MAV Buscà, IF Codina, JFM López, AM Pintó, XP Sala, ... Anales espanoles de pediatria 56 (5), 402-408, 2002 | 10 | 2002 |
| 18O labeling on Ser45 but not on Ser35 supports the cooperative phosphorylation mechanism on tarantula thick filament activation G Sulbarán, A Biasutto, F Méndez, A Pinto, L Alamo, R Padrón Biochemical and Biophysical Research Communications 524 (1), 198-204, 2020 | 4 | 2020 |
| The Inhibited, Interacting-Heads Motif Characterizes Myosin II from the Earliest Animals with Muscles G Sulbarán, JY Mun, KH Lee, L Alamo, A Pinto, O Sato, M Ikebe, X Liu, ... Biophysical Journal 108 (2), 301a, 2015 | 4 | 2015 |
| A method for 3D-reconstruction of a muscle thick filament using the tilt series images of a single filament electron tomogram G Márquez, A Pinto, L Alamo, B Baumann, F Ye, H Winkler, K Taylor, ... Journal of structural biology 186 (2), 265-272, 2014 | 3 | 2014 |
| Hiperhomocistinemia y polimorfismo 677C→ T de la 5, 10-metilenotetrahidrofolato reductasa en hijos de pacientes con enfermedad coronaria prematura CM Cid, NG Giralt, IF Codina, JFM López, AM Pintó, XP Sala, ... Anales de Pediatría 56 (5), 402-408, 2002 | 3 | 2002 |
Raul PadronProfessor, UMass Chan Medical SchoolVerified email at umassmed.edu
