De novo design of a fluorescence-activating β-barrel J Dou, AA Vorobieva, W Sheffler, LA Doyle, H Park, MJ Bick, B Mao, ... Nature 561 (7724), 485-491, 2018 | 320 | 2018 |
Transformation efficiency of RasQ61 mutants linked to structural features of the switch regions in the presence of Raf G Buhrman, G Wink, C Mattos Structure 15 (12), 1618-1629, 2007 | 127 | 2007 |
Designed BH3 peptides with high affinity and specificity for targeting Mcl-1 in cells GW Foight, JA Ryan, SV Gullá, A Letai, AE Keating ACS chemical biology 9 (9), 1962-1968, 2014 | 111 | 2014 |
Multi-input chemical control of protein dimerization for programming graded cellular responses GW Foight, Z Wang, CT Wei, P Jr Greisen, KM Warner, ... Nature biotechnology 37 (10), 1209-1216, 2019 | 74 | 2019 |
Multiple solvent crystal structures of ribonuclease A: an assessment of the method M Dechene, G Wink, M Smith, P Swartz, C Mattos Proteins: Structure, Function, and Bioinformatics 76 (4), 861-881, 2009 | 51 | 2009 |
Comparison of the peptide binding preferences of three closely related TRAF paralogs: TRAF2, TRAF3, and TRAF5 GW Foight, AE Keating Protein Science 25 (7), 1273-1289, 2016 | 30 | 2016 |
Locating herpesvirus Bcl-2 homologs in the specificity landscape of anti-apoptotic Bcl-2 proteins GW Foight, AE Keating Journal of molecular biology 427 (15), 2468-2490, 2015 | 25 | 2015 |
A chemically disrupted proximity system for controlling dynamic cellular processes D Cunningham-Bryant, EM Dieter, GW Foight, JC Rose, DE Loutey, ... Journal of the American Chemical Society 141 (8), 3352-3355, 2019 | 23 | 2019 |
Selective peptide inhibitors of antiapoptotic cellular and viral Bcl-2 proteins lead to cytochrome c release during latent Kaposi’s sarcoma-associated herpesvirus infection CM Burrer, GW Foight, AE Keating, GC Chan Virus research 211, 86-88, 2016 | 10 | 2016 |
BH3 profiling predicts clinical response in a phase II clinical trial of ABT-199 (GDC-0199) in acute myeloid leukemia L Hogdal, B Chyla, E McKeegan, J Leverson, J Potluri, N Falotico, ... Cancer Research 75 (15_Supplement), 2834-2834, 2015 | 6 | 2015 |
Enriching peptide libraries for binding affinity and specificity through computationally directed library design GW Foight, TS Chen, D Richman, AE Keating Modeling Peptide-Protein Interactions: Methods and Protocols, 213-232, 2017 | 5 | 2017 |
Synthetic transcription factor engineering for cell and gene therapy B Bhatt, P García-Díaz, GW Foight Trends in Biotechnology, 2023 | 4 | 2023 |
Reagents and methods for controlling protein function and interaction D Baker, D Cunningham-bryant, E Dieter, G Foight, P Greisen, D Maly, ... US Patent App. 17/297,606, 2022 | 1 | 2022 |
Determinants of protein-peptide interaction specificity in the Bcl-2 and TRAF families GW Foight Massachusetts Institute of Technology, 2015 | | 2015 |