| Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities M Cnop, N Welsh, JC Jonas, A Jorns, S Lenzen, DL Eizirik Diabetes 54 (suppl_2), S97-S107, 2005 | 1946 | 2005 |
| Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines E Gurgul, S Lortz, M Tiedge, A Jorns, S Lenzen Diabetes 53 (9), 2271-2280, 2004 | 167 | 2004 |
| Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes M Solimena, AM Schulte, L Marselli, F Ehehalt, D Richter, M Kleeberg, ... Diabetologia 61, 641-657, 2018 | 152 | 2018 |
| The LEW. 1AR1/Ztm-iddm rat: a new model of spontaneous insulin-dependent diabetes mellitus S Lenzen, M Tiedge, M Elsner, S Lortz, H Weiss, A Jörns, G Klöppel, ... Diabetologia 44, 1189-1196, 2001 | 147 | 2001 |
| Norovirus triggered microbiota-driven mucosal inflammation in interleukin 10-deficient mice M Basic, LM Keubler, M Buettner, M Achard, G Breves, B Schröder, ... Inflammatory bowel diseases 20 (3), 431-443, 2014 | 146 | 2014 |
| Immune cell infiltration, cytokine expression, and β-cell apoptosis during the development of type 1 diabetes in the spontaneously diabetic LEW. 1AR1/Ztm-iddm rat A Jorns, A Gunther, HJ Hedrich, D Wedekind, M Tiedge, S Lenzen Diabetes 54 (7), 2041-2052, 2005 | 142 | 2005 |
| MIN6 β-cell–β-cell interactions influence insulin secretory responses to nutrients and non-nutrients MJ Luther, A Hauge-Evans, KLA Souza, A Jörns, S Lenzen, SJ Persaud, ... Biochemical and biophysical research communications 343 (1), 99-104, 2006 | 108 | 2006 |
| Effect of superoxide dismutase, catalase, chelating agents, and free radical scavengers on the toxicity of alloxan to isolated pancreatic islets in vitro A Jörns, M Tiedge, S Lenzen, R Munday Free Radical Biology and Medicine 26 (9-10), 1300-1304, 1999 | 100 | 1999 |
| Alloxan derivatives as a tool for the elucidation of the mechanism of the diabetogenic action of alloxan S Lenzen, M Tiedge, A Jörns, R Munday Lessons from Animal Diabetes VI: 75th Anniversary of the Insulin Discovery …, 1996 | 100 | 1996 |
| Chromogranin A (CGA) in the gastro-entero-pancreatic (GEP) endocrine system: I. CGA in the mammalian endocrine pancreas D Grube, D Aunis, F Bader, Y Cetin, A Jörns, S Yoshie Histochemistry 85 (6), 441-452, 1986 | 95 | 1986 |
| Islet infiltration, cytokine expression and beta cell death in the NOD mouse, BB rat, Komeda rat, LEW.1AR1-iddm rat and humans with type 1 diabetes A Jörns, T Arndt, AM Zu Vilsendorf, J Klempnauer, D Wedekind, ... Diabetologia 57, 512-521, 2014 | 91 | 2014 |
| Antagonism between saturated and unsaturated fatty acids in ROS mediated lipotoxicity in rat insulin-producing cells W Gehrmann, W Würdemann, T Plötz, A Jörns, S Lenzen, M Elsner Cellular Physiology and Biochemistry 36 (3), 852-865, 2015 | 80 | 2015 |
| Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines E Gurgul-Convey, I Mehmeti, T Plötz, A Jörns, S Lenzen Diabetologia 59, 2125-2133, 2016 | 69 | 2016 |
| Gradual loss of pancreatic beta-cell insulin, glucokinase and GLUT2 glucose transporter immunoreactivities during the time course of nutritionally induced type-2 diabetes in … A Jörns, M Tiedge, E Ziv, E Shafrir, S Lenzen Virchows Archiv 440, 63-69, 2002 | 69 | 2002 |
| Chromostatin, a chromogranin A-derived bioactive peptide, is present in human pancreatic insulin (beta) cells. Y Cetin, D Aunis, MF Bader, E Galindo, A Jörns, G Bargsten, D Grube Proceedings of the National Academy of Sciences 90 (6), 2360-2364, 1993 | 68 | 1993 |
| The central role of glutathione peroxidase 4 in the regulation of ferroptosis and its implications for pro-inflammatory cytokine-mediated beta-cell death B Krümmel, T Plötz, A Jörns, S Lenzen, I Mehmeti Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1867 (6), 166114, 2021 | 65 | 2021 |
| Interleukin 17, produced by γδ T cells, contributes to hepatic inflammation in a mouse model of biliary atresia and is increased in livers of patients C Klemann, A Schröder, A Dreier, N Möhn, S Dippel, T Winterberg, ... Gastroenterology 150 (1), 229-241. e5, 2016 | 63 | 2016 |
| Thyroxine induces pancreatic beta-cell apoptosis in rats A Jörns, M Tiedge, S Lenzen Diabetologia 45, 851-855, 2002 | 62 | 2002 |
| Reversal of diabetes through gene therapy of diabetic rats by hepatic insulin expression via lentiviral transduction M Elsner, T Terbish, A Jörns, O Naujok, D Wedekind, HJ Hedrich, ... Molecular Therapy 20 (5), 918-926, 2012 | 60 | 2012 |
| Desensitization of insulin secretion by depolarizing insulin secretagogues I Rustenbeck, A Wienbergen, C Bleck, A Jorns Diabetes 53 (suppl_3), S140-S150, 2004 | 60 | 2004 |
