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Sema Kurtulus
Sema Kurtulus
Postdoctoral Fellow, Harvard Medical School
Verified email at research.bwh.harvard.edu
Title
Cited by
Cited by
Year
TIGIT predominantly regulates the immune response via regulatory T cells
S Kurtulus, K Sakuishi, SF Ngiow, N Joller, DJ Tan, MWL Teng, MJ Smyth, ...
The Journal of clinical investigation 125 (11), 4053-4062, 2015
5482015
Checkpoint blockade immunotherapy induces dynamic changes in PD-1− CD8+ tumor-infiltrating T cells
S Kurtulus, A Madi, G Escobar, M Klapholz, J Nyman, E Christian, ...
Immunity 50 (1), 181-194. e6, 2019
5132019
TIGIT and CD 96: new checkpoint receptor targets for cancer immunotherapy
WC Dougall, S Kurtulus, MJ Smyth, AC Anderson
Immunological reviews 276 (1), 112-120, 2017
4142017
A distinct gene module for dysfunction uncoupled from activation in tumor-infiltrating T cells
M Singer, C Wang, L Cong, ND Marjanovic, MS Kowalczyk, H Zhang, ...
Cell 166 (6), 1500-1511. e9, 2016
4012016
Induction and transcriptional regulation of the co-inhibitory gene module in T cells
N Chihara, A Madi, T Kondo, H Zhang, N Acharya, M Singer, J Nyman, ...
Nature 558 (7710), 454-459, 2018
3842018
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells
M Guimond, RG Veenstra, DJ Grindler, H Zhang, Y Cui, RD Murphy, ...
Nature immunology 10 (2), 149-157, 2009
2802009
STAT5 is critical to maintain effector CD8+ T cell responses
P Tripathi, S Kurtulus, S Wojciechowski, A Sholl, K Hoebe, SC Morris, ...
The Journal of Immunology 185 (4), 2116-2124, 2010
1482010
Functional anti-TIGIT antibodies regulate development of autoimmunity and antitumor immunity
KO Dixon, M Schorer, J Nevin, Y Etminan, Z Amoozgar, T Kondo, ...
The Journal of Immunology 200 (8), 3000-3007, 2018
1352018
Bcl-2 allows effector and memory CD8+ T cells to tolerate higher expression of Bim
S Kurtulus, P Tripathi, ME Moreno-Fernandez, A Sholl, JD Katz, ...
The Journal of Immunology 186 (10), 5729-5737, 2011
1172011
Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus
TM McCaughtry, R Etzensperger, A Alag, X Tai, S Kurtulus, JH Park, ...
Journal of Experimental Medicine 209 (12), 2263-2276, 2012
982012
Efficacy and safety of sabatolimab (MBG453) in combination with hypomethylating agents (HMAs) in patients with acute myeloid leukemia (AML) and high-risk myelodysplastic …
AM Brunner, J Esteve, K Porkka, S Knapper, N Vey, S Scholl, ...
Blood 136, 1-2, 2020
762020
Protecting and rescuing the effectors: roles of differentiation and survival in the control of memory T cell development
S Kurtulus, P Tripathi, DA Hildeman
Frontiers in immunology 3, 404, 2013
532013
Contracting the ‘mus cells’–does down‐sizing suit us for diving into the memory pool?
S Kurtulus, P Tripathi, JT Opferman, DA Hildeman
Immunological reviews 236 (1), 54-67, 2010
402010
Inhibition of MDM2 promotes antitumor responses in p53 wild-type cancer cells through their interaction with the immune and stromal microenvironment
HQ Wang, IJ Mulford, F Sharp, J Liang, S Kurtulus, G Trabucco, DS Quinn, ...
Cancer Research 81 (11), 3079-3091, 2021
362021
Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors
K Conlon, DC Watson, TA Waldmann, A Valentin, C Bergamaschi, ...
Journal for immunotherapy of cancer 9 (11), 2021
262021
CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1
DL Ligons, C Tuncer, BA Linowes, IM Akcay, S Kurtulus, E Deniz, ...
Journal of Biological Chemistry 287 (41), 34386-34399, 2012
262012
T-cell receptor signal strength and epigenetic control of Bim predict memory CD8+ T-cell fate
KP Li, BH Ladle, S Kurtulus, A Sholl, S Shanmuganad, DA Hildeman
Cell Death & Differentiation 27 (4), 1214-1224, 2020
212020
Bim controls IL-15 availability and limits engagement of multiple BH3-only proteins
S Kurtulus, A Sholl, J Toe, P Tripathi, J Raynor, KP Li, M Pellegrini, ...
Cell Death & Differentiation 22 (1), 174-184, 2015
202015
Assessment of CD4+ and CD8+ T Cell Responses Using MHC Class I and II Tetramers
S Kurtulus, D Hildeman
Immune Homeostasis: Methods and Protocols, 71-79, 2013
182013
Mechanisms of TIGIT-driven immune suppression in cancer
S Kurtulus, K Sakuishi, H Zhang, N Joller, D Tan, M Smyth, V Kuchroo, ...
Journal for Immunotherapy of Cancer 2, 1-1, 2014
122014
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