TIGIT predominantly regulates the immune response via regulatory T cells S Kurtulus, K Sakuishi, SF Ngiow, N Joller, DJ Tan, MWL Teng, MJ Smyth, ... The Journal of clinical investigation 125 (11), 4053-4062, 2015 | 548 | 2015 |
Checkpoint blockade immunotherapy induces dynamic changes in PD-1− CD8+ tumor-infiltrating T cells S Kurtulus, A Madi, G Escobar, M Klapholz, J Nyman, E Christian, ... Immunity 50 (1), 181-194. e6, 2019 | 513 | 2019 |
TIGIT and CD 96: new checkpoint receptor targets for cancer immunotherapy WC Dougall, S Kurtulus, MJ Smyth, AC Anderson Immunological reviews 276 (1), 112-120, 2017 | 414 | 2017 |
A distinct gene module for dysfunction uncoupled from activation in tumor-infiltrating T cells M Singer, C Wang, L Cong, ND Marjanovic, MS Kowalczyk, H Zhang, ... Cell 166 (6), 1500-1511. e9, 2016 | 401 | 2016 |
Induction and transcriptional regulation of the co-inhibitory gene module in T cells N Chihara, A Madi, T Kondo, H Zhang, N Acharya, M Singer, J Nyman, ... Nature 558 (7710), 454-459, 2018 | 384 | 2018 |
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells M Guimond, RG Veenstra, DJ Grindler, H Zhang, Y Cui, RD Murphy, ... Nature immunology 10 (2), 149-157, 2009 | 280 | 2009 |
STAT5 is critical to maintain effector CD8+ T cell responses P Tripathi, S Kurtulus, S Wojciechowski, A Sholl, K Hoebe, SC Morris, ... The Journal of Immunology 185 (4), 2116-2124, 2010 | 148 | 2010 |
Functional anti-TIGIT antibodies regulate development of autoimmunity and antitumor immunity KO Dixon, M Schorer, J Nevin, Y Etminan, Z Amoozgar, T Kondo, ... The Journal of Immunology 200 (8), 3000-3007, 2018 | 135 | 2018 |
Bcl-2 allows effector and memory CD8+ T cells to tolerate higher expression of Bim S Kurtulus, P Tripathi, ME Moreno-Fernandez, A Sholl, JD Katz, ... The Journal of Immunology 186 (10), 5729-5737, 2011 | 117 | 2011 |
Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus TM McCaughtry, R Etzensperger, A Alag, X Tai, S Kurtulus, JH Park, ... Journal of Experimental Medicine 209 (12), 2263-2276, 2012 | 98 | 2012 |
Efficacy and safety of sabatolimab (MBG453) in combination with hypomethylating agents (HMAs) in patients with acute myeloid leukemia (AML) and high-risk myelodysplastic … AM Brunner, J Esteve, K Porkka, S Knapper, N Vey, S Scholl, ... Blood 136, 1-2, 2020 | 76 | 2020 |
Protecting and rescuing the effectors: roles of differentiation and survival in the control of memory T cell development S Kurtulus, P Tripathi, DA Hildeman Frontiers in immunology 3, 404, 2013 | 53 | 2013 |
Contracting the ‘mus cells’–does down‐sizing suit us for diving into the memory pool? S Kurtulus, P Tripathi, JT Opferman, DA Hildeman Immunological reviews 236 (1), 54-67, 2010 | 40 | 2010 |
Inhibition of MDM2 promotes antitumor responses in p53 wild-type cancer cells through their interaction with the immune and stromal microenvironment HQ Wang, IJ Mulford, F Sharp, J Liang, S Kurtulus, G Trabucco, DS Quinn, ... Cancer Research 81 (11), 3079-3091, 2021 | 36 | 2021 |
Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors K Conlon, DC Watson, TA Waldmann, A Valentin, C Bergamaschi, ... Journal for immunotherapy of cancer 9 (11), 2021 | 26 | 2021 |
CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1 DL Ligons, C Tuncer, BA Linowes, IM Akcay, S Kurtulus, E Deniz, ... Journal of Biological Chemistry 287 (41), 34386-34399, 2012 | 26 | 2012 |
T-cell receptor signal strength and epigenetic control of Bim predict memory CD8+ T-cell fate KP Li, BH Ladle, S Kurtulus, A Sholl, S Shanmuganad, DA Hildeman Cell Death & Differentiation 27 (4), 1214-1224, 2020 | 21 | 2020 |
Bim controls IL-15 availability and limits engagement of multiple BH3-only proteins S Kurtulus, A Sholl, J Toe, P Tripathi, J Raynor, KP Li, M Pellegrini, ... Cell Death & Differentiation 22 (1), 174-184, 2015 | 20 | 2015 |
Assessment of CD4+ and CD8+ T Cell Responses Using MHC Class I and II Tetramers S Kurtulus, D Hildeman Immune Homeostasis: Methods and Protocols, 71-79, 2013 | 18 | 2013 |
Mechanisms of TIGIT-driven immune suppression in cancer S Kurtulus, K Sakuishi, H Zhang, N Joller, D Tan, M Smyth, V Kuchroo, ... Journal for Immunotherapy of Cancer 2, 1-1, 2014 | 12 | 2014 |