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Prabhu Thirusangu
Prabhu Thirusangu
Mayo Clinic, Rochester, MN
Verified email at mayo.edu - Homepage
Title
Cited by
Cited by
Year
Synthesis and tumor inhibitory activity of novel coumarin analogs targeting angiogenesis and apoptosis
BRV Avin, P Thirusangu, VL Ranganatha, A Firdouse, BT Prabhakar, ...
European journal of medicinal chemistry 75, 211-221, 2014
1172014
Repurposing quinacrine for treatment-refractory cancer
DB Oien, CL Pathoulas, U Ray, P Thirusangu, E Kalogera, V Shridhar
Seminars in Cancer Biology 68, 21-30, 2021
682021
BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation
P Thirusangu, V Vigneshwaran, T Prashanth, BRV Avin, VH Malojirao, ...
Angiogenesis 20 (1), 55–71, 2017
502017
Synthesis and evaluation of novel benzophenone-thiazole derivatives as potent VEGF-A inhibitors
T Prashanth, P Thirusangu, BRV Avin, VL Ranganatha, BT Prabhakar, ...
European journal of medicinal chemistry 87, 274-283, 2014
492014
Synthesis, angiopreventive activity, and in vivo tumor inhibition of novel benzophenone–benzimidazole analogs
VL Ranganatha, BRV Avin, P Thirusangu, T Prashanth, BT Prabhakar, ...
Life sciences 93 (23), 904-911, 2013
482013
Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma
T Prashanth, BRV Avin, P Thirusangu, VL Ranganatha, BT Prabhakar, ...
Biomedicine & Pharmacotherapy 112, 108707, 2019
452019
A tumoural angiogenic gateway blocker, Benzophenone-1B represses the HIF-1α nuclear translocation and its target gene activation against neoplastic progression
P Thirusangu, V Vigneshwaran, VL Ranganatha, BRV Avin, SA Khanum, ...
Biochemical Pharmacology 125, 26-40, 2017
442017
Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer
Y Xiao, L Jin, C Deng, Y Guan, E Kalogera, U Ray, P Thirusangu, J Staub, ...
Oncogene, 1-16, 2021
382021
DAO-9 (2, 5-di (4-aryloylaryloxymethyl)-1, 3, 4-oxadiazole) exhibits p53 induced apoptogenesis through caspase-3 mediated endonuclease activity in murine carcinoma
HD Gurupadaswamy, P Thirusangu, BRV Avin, V Vigneshwaran, ...
Biomedicine & Pharmacotherapy 68 (6), 791-797, 2014
362014
New role of lupeol in reticence of angiogenesis, the cellular parameter of neoplastic progression in tumorigenesis models through altered gene expression
BRV Avin, T Prabhu, CK Ramesh, V Vigneshwaran, M Riaz, K Jayashree, ...
Biochemical and Biophysical Research Communications 448 (2), 139-144, 2014
362014
PFKFB3 inhibition reprograms malignant pleural mesothelioma to nutrient stress-induced macropinocytosis and ER stress as independent binary adaptive responses
S Sarkar Bhattacharya, P Thirusangu, L Jin, D Roy, D Jung, Y Xiao, ...
Cell Death & Disease 10 (10), 725, 2019
352019
Synthesis and antiproliferative activity of benzophenone tagged pyridine analogues towards activation of caspase activated DNase mediated nuclear fragmentation in Dalton’s lymphoma
M Al-Ghorbani, P Thirusangu, HD Gurupadaswamy, V Girish, ...
Bioorganic chemistry 65, 73-81, 2016
342016
The Novel 4-Phenyl-2-Phenoxyacetamide Thiazoles modulates the tumor hypoxia leading to the crackdown of neoangiogenesis and evoking the cell death
YHE Mohammed, VH Malojirao, P Thirusangu, M Al-Ghorbani, ...
European journal of medicinal chemistry 143, 1826-1839, 2018
312018
Targeting LRRC15 inhibits metastatic dissemination of ovarian cancer
U Ray, DB Jung, L Jin, Y Xiao, S Dasari, S Sarkar Bhattacharya, ...
Cancer research 82 (6), 1038-1054, 2022
292022
Scutellarein antagonizes the tumorigenesis by modulating cytokine VEGF mediated neoangiogenesis and DFF-40 actuated nucleosomal degradation
P Thirusangu, V Vigneshwaran, BRV Avin, H Rakesh, HM Vikas, ...
Biochemical and biophysical research communications 484 (1), 85-92, 2017
292017
PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinoma
P Thirusangu, U Ray, S Sarkar Bhattacharya, DB Oien, L Jin, J Staub, ...
Oncogene 41 (33), 4003-4017, 2022
282022
Immunomodulatory glc/man-directed Dolichos lablab lectin (DLL) evokes anti-tumour response in vivo by counteracting angiogenic gene expressions
V Vigneshwaran, P Thirusangu, BR Vijay Avin, V Krishna, SN Pramod, ...
Clinical & Experimental Immunology 189 (1), 21-35, 2017
262017
The latex sap of the ‘Old World Plant’Lagenaria siceraria with potent lectin activity mitigates neoplastic malignancy targeting neovasculature and cell death
V Vigneshwaran, P Thirusangu, S Madhusudana, V Krishna, SN Pramod, ...
International Immunopharmacology 39, 158-171, 2016
252016
Synthesis and an angiolytic role of novel piperazine–benzothiazole analogues on neovascularization, a chief tumoral parameter in neoplastic development
M Al-Ghorbani, GS Pavankumar, P Naveen, P Thirusangu, BT Prabhakar, ...
Bioorganic chemistry 65, 110-117, 2016
242016
Quinacrine-induced autophagy in ovarian cancer triggers cathepsin-l mediated lysosomal/mitochondrial membrane permeabilization and cell death
P Thirusangu, CL Pathoulas, U Ray, Y Xiao, J Staub, L Jin, A Khurana, ...
Cancers 13 (9), 2004, 2021
202021
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