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Steffen Kutter
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Evolutionary drivers of thermoadaptation in enzyme catalysis
V Nguyen, C Wilson, M Hoemberger, JB Stiller, RV Agafonov, S Kutter, ...
Science 355 (6322), 289-294, 2017
1922017
Using ancient protein kinases to unravel a modern cancer drug’s mechanism
C Wilson, RV Agafonov, M Hoemberger, S Kutter, A Zorba, J Halpin, ...
Science 347 (6224), 882-886, 2015
1862015
The energy landscape of adenylate kinase during catalysis
SJ Kerns, RV Agafonov, YJ Cho, F Pontiggia, R Otten, DV Pachov, ...
Nature Structural & Molecular Biology 22 (2), 124-131, 2015
1722015
Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2
A Zorba, V Buosi, S Kutter, N Kern, F Pontiggia, YJ Cho, D Kern
Elife 3, e02667, 2014
1472014
Covalently bound substrate at the regulatory site of yeast pyruvate decarboxylases triggers allosteric enzyme activation
S Kutter, MS Weiss, G Wille, R Golbik, M Spinka, S König
Journal of Biological Chemistry 284 (18), 12136-12144, 2009
512009
Dynamics of human protein kinase Aurora A linked to drug selectivity
W Pitsawong, V Buosi, R Otten, RV Agafonov, A Zorba, N Kern, S Kutter, ...
eLife 7, e36656, 2018
392018
Allosteric modulation of a human protein kinase with monobodies
A Zorba, V Nguyen, A Koide, M Hoemberger, Y Zheng, S Kutter, C Kim, ...
Proceedings of the National Academy of Sciences 116 (28), 13937-13942, 2019
352019
The crystal structure of pyruvate decarboxylase from Kluyveromyces lactis: Implications for the substrate activation mechanism of this enzyme
S Kutter, G Wille, S Relle, MS Weiss, G Hübner, S König
The FEBS Journal 273 (18), 4199-4209, 2006
312006
The crystal structure of pyruvate decarboxylase from Kluyveromyces lactis. Implications for the substrate activation mechanism of this enzyme
S Kutter, G Wille, MS Weiss, G Hübner, S König
Hasylab Annual Report 2006, 229-230, 2006
312006
The crystal structure of pyruvate decarboxylase from Kluyveromyces lactis
S Kutter, S Relle, G Wille, MS Weiss, G Hübner, S König
Hasylab Annual Report 2005, 307-308, 2005
31*2005
Regulation of microtubule assembly by tau and not by Pin1
S Kutter, T Eichner, AM Deaconescu, D Kern
Journal of Molecular Biology 428 (9), 1742-1759, 2016
252016
Molecular Mechanism of Pin1–Tau Recognition and Catalysis
T Eichner, S Kutter, W Labeikovsky, V Buosi, D Kern
Journal of Molecular Biology 428 (9), 1760-1775, 2016
252016
Allosteric activation of pyruvate decarboxylases. A never-ending story?
S König, M Spinka, S Kutter
Journal of Molecular Catalysis B: Enzymatic 61 (1-2), 100-110, 2009
242009
The influence of protein concentration on oligomer structure and catalytic function of two pyruvate decarboxylases
S Kutter, M Spinka, MHJ Koch, S König
The Protein Journal 26 (8), 585-591, 2007
112007
Catalytically active filaments–pyruvate decarboxylase from Neurospora crassa. pH‐controlled oligomer structure and catalytic function
S Hüttl, J Fiebig, S Kutter, G Hause, H Lilie, M Spinka, S König
The FEBS Journal 279 (2), 275-284, 2012
32012
Die Regulation der Pyruvatdecarboxylasen aus den Schlauchpilzen Kluyveromyces lactis, Saccharomyces cerevisiae und Neurospora crassa
S Kutter
Martin-Luther-Universität Halle-Wittenberg, Institut für Biochemie …, 2009
22009
Covalently bound substrate at the regulatory site triggers allosteric enzyme activation
S Kutter, M Weiss, G Wille, R Golbik, M Spinka, S König
Nature Precedings, 10101/npre.2008.1639.1, 2008
12008
Determination of binding constants for activating ligands of pyruvate decarboxylase from Kluyveromyces lactis using SAXS parameters
S Kutter, R Golbik, P Konarev, DI Svergun, S König
Hasylab Annual Report 2006, 319-320, 2006
12006
The crystal structures of pyruvate decarboxylase from Kluyveromyces lactis in the absence of ligands and in the presence of the substrate surrogate pyruvamide
S Kutter, S Köning
https://zenodo.org/record/1327432, 2018
2018
Dynamics of human protein kinases linked to drug selectivity [preprint]
D Kern, W Pitsawong, R Otten, RV Agafonov, A Zorba, N Kern, S Kutter, ...
2018
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Articles 1–20