| Selective interactions between G protein subunits and RGS4 with the C-terminal domains of the μ-and δ-opioid receptors regulate opioid receptor signaling Z Georgoussi, L Leontiadis, G Mazarakou, M Merkouris, K Hyde, H Hamm Cellular signalling 18 (6), 771-782, 2006 | 117 | 2006 |
| Stably transformed insect cell lines: tools for expression of secreted and membrane‐anchored proteins and high‐throughput screening platforms for drug and insecticide discovery V Douris, L Swevers, V Labropoulou, E Andronopoulou, Z Georgoussi, ... Advances in virus research 68, 113-156, 2006 | 114 | 2006 |
| Expression and Membrane Topology of Anopheles gambiae Odorant Receptors in Lepidopteran Insect Cells P Tsitoura, E Andronopoulou, D Tsikou, A Agalou, MP Papakonstantinou, ... PloS one 5 (11), e15428, 2010 | 73 | 2010 |
| Identification of the critical domains of the delta-opioid receptor involved in G protein coupling using site-specific synthetic peptides. M Merkouris, I Dragatsis, G Megaritis, G Konidakis, C Zioudrou, G Milligan, ... Molecular Pharmacology 50 (4), 985-993, 1996 | 63 | 1996 |
| Regulator of G protein signaling 4 confers selectivity to specific G proteins to modulate μ-and δ-opioid receptor signaling LJ Leontiadis, MP Papakonstantinou, Z Georgoussi Cellular signalling 21 (7), 1218-1228, 2009 | 56 | 2009 |
| Selective interactions of μ-opioid receptors with pertussis toxin-sensitive G proteins: involvement of the third intracellular loop and the c-terminal tail in coupling Z Georgoussi, M Merkouris, I Mullaney, G Megaritis, C Carr, C Zioudrou, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1359 (3), 263-274, 1997 | 54 | 1997 |
| Regulation of spontaneous activity of the δ‐opioid receptor: Studies of inverse agonism in intact cells M Merkouris, I Mullaney, Z Georgoussi, G Milligan Journal of neurochemistry 69 (5), 2115-2122, 1997 | 54 | 1997 |
| The other side of opioid receptor signalling: regulation by protein-protein interaction Z Georgoussi, EM Georganta, G Milligan Current drug targets 13 (1), 80-102, 2012 | 49 | 2012 |
| Functional domains of delta-and mu-opioid receptors responsible for adenylyl cyclase inhibition. G Megaritis, M Merkouris, Z Georgoussi Receptors & channels 7 (3), 199-212, 2000 | 49 | 2000 |
| Evaluation of N-substitution in 6, 7-benzomorphan compounds L Pasquinucci, O Prezzavento, A Marrazzo, E Amata, S Ronsisvalle, ... Bioorganic & medicinal chemistry 18 (14), 4975-4982, 2010 | 46 | 2010 |
| Immunoprecipitation of opioid receptor-Go-protein complexes using specific GTP-binding-protein antisera Z Georgoussi, G Milligan, C Zioudrou Biochemical Journal 306 (1), 71-75, 1995 | 44 | 1995 |
| STAT5A interacts with and is phosphorylated upon activation of the µ‐opioid receptor G Mazarakou, Z Georgoussi Journal of neurochemistry 93 (4), 918-931, 2005 | 42 | 2005 |
| Expression of the third intracellular loop of the δ-opioid receptor inhibits signaling by opioid receptors and other G protein-coupled receptors E Morou, Z Georgoussi Journal of Pharmacology and Experimental Therapeutics 315 (3), 1368-1379, 2005 | 36 | 2005 |
| Direct measurements of in situ interactions of rat brain opioid receptors with the guanine nucleotide-binding protein Go. Z Georgoussi, C Carr, G Milligan Molecular pharmacology 44 (1), 62-69, 1993 | 34 | 1993 |
| The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment L Pasquinucci, C Parenti, R Turnaturi, G Aricò, A Marrazzo, ... Life sciences 90 (1-2), 66-70, 2012 | 32 | 2012 |
| Somatostatin receptors (sst2) are coupled to Go and modulate GTPase activity in the rabbit retina A Vasilaki, Z Georgoussi, K Thermos Journal of neurochemistry 84 (4), 625-632, 2003 | 30 | 2003 |
| Superpotent [Dmt1]Dermorphin Tetrapeptides Containing the 4-Aminotetrahydro-2-benzazepin-3-one Scaffold with Mixed μ/δ Opioid Receptor Agonistic Properties B Vandormael, DD Fourla, A Gramowski-Voß, P Kosson, DG Weiss, ... Journal of medicinal chemistry 54 (22), 7848-7859, 2011 | 28 | 2011 |
| Effect of δ-opioid antagonists on the functional coupling between opioid receptors and G-proteins in rat brain membranes Z Georgoussi, C Zioudrou Biochemical pharmacology 45 (12), 2405-2410, 1993 | 28 | 1993 |
| δ‐opioid receptor activation leads to neurite outgrowth and neuronal differentiation via a STAT 5B‐Gαi/o pathway EM Georganta, L Tsoutsi, M Gaitanou, Z Georgoussi Journal of Neurochemistry 127 (3), 329-341, 2013 | 25 | 2013 |
| Multi-component signaling complexes of the δ-opioid receptor with STAT5B and G proteins EM Georganta, A Agalou, Z Georgoussi Neuropharmacology 59 (3), 139-148, 2010 | 25 | 2010 |
