Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming A Ebrahimi, K Sevinç, G Gürhan Sevinç, AP Cribbs, M Philpott, F Uyulur, ... Nature chemical biology 15 (5), 519-528, 2019 | 84 | 2019 |
Sulfated levan from Halomonas smyrnensis as a bioactive, heparin-mimetic glycan for cardiac tissue engineering applications M Erginer, A Akcay, B Coskunkan, T Morova, D Rende, S Bucak, N Baysal, ... Carbohydrate polymers 149, 289-296, 2016 | 83 | 2016 |
Androgen receptor-binding sites are highly mutated in prostate cancer T Morova, DR McNeill, N Lallous, M Gönen, K Dalal, DM Wilson III, ... Nature communications 11 (1), 832, 2020 | 53 | 2020 |
Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancer H Saraç, T Morova, E Pires, J McCullagh, A Kaplan, A Cingöz, ... Oncogene 39 (10), 2187-2201, 2020 | 32 | 2020 |
Drug-induced epigenomic plasticity reprograms circadian rhythm regulation to drive prostate cancer toward androgen independence S Linder, M Hoogstraat, S Stelloo, N Eickhoff, K Schuurman, H de Barros, ... Cancer discovery 12 (9), 2074-2097, 2022 | 25 | 2022 |
Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation SC Baca, C Singler, S Zacharia, JH Seo, T Morova, F Hach, Y Ding, ... Nature genetics 54 (9), 1364-1375, 2022 | 22 | 2022 |
Functional mapping of androgen receptor enhancer activity CCF Huang, S Lingadahalli, T Morova, D Ozturan, E Hu, IPL Yu, S Linder, ... Genome biology 22 (1), 149, 2021 | 20 | 2021 |
Androgen receptor-mediated transcription in prostate cancer D Özturan, T Morova, NA Lack Cells 11 (5), 898, 2022 | 18 | 2022 |
EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities O Yedier-Bayram, B Gokbayrak, A Kayabolen, AC Aksu, AD Cavga, ... Cell Death & Disease 13 (8), 710, 2022 | 9 | 2022 |
Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential J Kneppers, TM Severson, JC Siefert, P Schol, SEP Joosten, IPL Yu, ... Nature Communications 13 (1), 7367, 2022 | 7 | 2022 |
DNA binding alters ARv7 dimer interactions F Özgün, Z Kaya, T Morova, B Geverts, TE Abraham, AB Houtsmuller, ... Journal of cell science 134 (14), jcs258332, 2021 | 7 | 2021 |
Specific cannabinoids revive adaptive immunity by reversing immune evasion mechanisms in metastatic tumours S Dada, SLS Ellis, C Wood, LL Nohara, C Dreier, NH Garcia, ... Frontiers in Immunology 13, 982082, 2023 | 6 | 2023 |
Optimized high-throughput screening of non-coding variants identified from genome-wide association studies T Morova, Y Ding, CCF Huang, F Sar, T Schwarz, C Giambartolomei, ... Nucleic Acids Research 51 (3), e18-e18, 2023 | 4 | 2023 |
Differentiation of peritubular myoid‐like cells from human induced pluripotent stem cells M Robinson, A Haegert, YY Li, T Morova, AYY Zhang, L Witherspoon, ... Advanced Biology 7 (7), 2200322, 2023 | 3 | 2023 |
Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic) 2-like protein (ASH2L) as a regulator of glioblastoma cell survival E Ozyerli-Goknar, EY Kala, AC Aksu, I Bulut, A Cingöz, S Nizamuddin, ... Cell Communication and Signaling 21 (1), 328, 2023 | 1 | 2023 |
Curcuphenol possesses an unusual histone deacetylase enhancing activity that counters immune escape in metastatic tumours SLS Ellis, S Dada, LL Nohara, I Saranchova, L Munro, CG Pfeifer, ... Frontiers in Pharmacology 14, 1119620, 2023 | 1 | 2023 |
Sulfated Halomonas levan as a heparin-mimetic bioactive glycan M Erginer, B Coskunkan, T Morova, D Rende, S Bucak, N Baysal, ... New Biotechnology, S151-S152, 2016 | 1 | 2016 |
Inference of Transcriptional Regulation From STARR-seq Data A Safaeesirat, H Taeb, E Tekoglu, T Morova, N Lack, E Emberly bioRxiv, 2024.03. 06.583826, 2024 | | 2024 |
Breast cancer risk SNPs converge on estrogen receptor binding sites commonly shared between breast tumors to locally alter estrogen signalling output SEP Joosten, S Gregoricchio, S Stelloo, E Yapici, F Huang, ... bioRxiv, 2023.10. 30.564691, 2023 | | 2023 |
HOXB13 alters chromatin accessibility in prostate cancer through interactions with the SWI/SNF complex S Lingadahalli, BE Fazlioglu, UB Altintas, A Cingoz, E Tekoglu, IPL Yu, ... bioRxiv, 2023.09. 04.556101, 2023 | | 2023 |