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Sorin Tunaru
Sorin Tunaru
Institute of Biochemistry, Romanian Academy
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Year
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
S Tunaru, J Kero, A Schaub, C Wufka, A Blaukat, K Pfeffer, S Offermanns
Nature medicine 9 (3), 352-355, 2003
8982003
An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81
K Ahmed, S Tunaru, C Tang, M Müller, A Gille, A Sassmann, J Hanson, ...
Cell metabolism 11 (4), 311-319, 2010
4032010
Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes
C Tang, K Ahmed, A Gille, S Lu, HJ Gröne, S Tunaru, S Offermanns
Nature medicine 21 (2), 173-177, 2015
3282015
Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors
S Tunaru, TF Althoff, RM Nüsing, M Diener, S Offermanns
Proceedings of the National Academy of Sciences 109 (23), 9179-9184, 2012
2632012
GPR109A, GPR109B and GPR81, a family of hydroxy-carboxylic acid receptors
K Ahmed, S Tunaru, S Offermanns
Trends in pharmacological sciences 30 (11), 557-562, 2009
2602009
Nicotinic acid–and monomethyl fumarate–induced flushing involves GPR109A expressed by keratinocytes and COX-2–dependent prostanoid formation in mice
J Hanson, A Gille, S Zwykiel, M Lukasova, BE Clausen, K Ahmed, ...
The Journal of clinical investigation 120 (8), 2910-2919, 2010
2152010
Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development
J Kero, K Ahmed, N Wettschureck, S Tunaru, T Wintermantel, E Greiner, ...
The Journal of clinical investigation 117 (9), 2399-2407, 2007
1512007
Characterization of determinants of ligand binding to the nicotinic acid receptor GPR109A (HM74A/PUMA-G)
S Tunaru, J Lättig, J Kero, G Krause, S Offermanns
Molecular Pharmacology 68 (5), 1271-1280, 2005
1462005
Conserved MIP receptor–ligand pair regulates Platynereis larval settlement
M Conzelmann, EA Williams, S Tunaru, N Randel, R Shahidi, A Asadulina, ...
Proceedings of the National Academy of Sciences 110 (20), 8224-8229, 2013
1222013
Nicotinic acid (niacin): new lipid-independent mechanisms of action and therapeutic potentials
M Lukasova, J Hanson, S Tunaru, S Offermanns
Trends in pharmacological sciences 32 (12), 700-707, 2011
1082011
Deorphanization of GPR109B as a receptor for the β-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis
K Ahmed, S Tunaru, CD Langhans, J Hanson, CW Michalski, S Kölker, ...
Journal of Biological Chemistry 284 (33), 21928-21933, 2009
962009
20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1
S Tunaru, R Bonnavion, I Brandenburger, J Preussner, D Thomas, ...
Nature communications 9 (1), 177, 2018
812018
Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63
A Niedernberg, S Tunaru, A Blaukat, A Ardati, E Kostenis
Cellular signalling 15 (4), 435-446, 2003
722003
Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis
K Schmitz, R Brunkhorst, N De Bruin, CA Mayer, A Häussler, N Ferreiros, ...
Acta neuropathologica communications 5, 1-18, 2017
502017
The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity
SW Hohmann, C Angioni, S Tunaru, S Lee, CJ Woolf, S Offermanns, ...
Scientific Reports 7 (1), 446, 2017
492017
Comparative analysis of functional assays for characterization of agonist ligands at G protein-coupled receptors
A Niedernberg, S Tunaru, A Blaukat, B Harris, E Kostenis
Journal of biomolecular screening 8 (5), 500-510, 2003
362003
A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development
CSM Helker, ST Mullapudi, LM Mueller, J Preussner, S Tunaru, O Skog, ...
Development 146 (14), dev172569, 2019
342019
Arachidonic acid metabolite 19 (S)-HETE induces vasorelaxation and platelet inhibition by activating prostacyclin (IP) receptor
S Tunaru, R Chennupati, RM Nüsing, S Offermanns
PloS one 11 (9), e0163633, 2016
302016
The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons
S Zinn, M Sisignano, K Kern, S Pierre, S Tunaru, H Jordan, J Suo, ...
Journal of Biological Chemistry 292 (15), 6123-6134, 2017
272017
A novel luminescence-based method for the detection of functionally active antibodies to muscarinic acetylcholine receptors of the M3 type (mAchR3) in patients' sera
B Preuss, S Tunaru, J Henes, S Offermanns, R Klein
Clinical & Experimental Immunology 177 (1), 179-189, 2014
272014
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Articles 1–20