| Ipragliflozin improves hepatic steatosis in obese mice and liver dysfunction in type 2 diabetic patients irrespective of body weight reduction C Komiya, K Tsuchiya, K Shiba, Y Miyachi, S Furuke, N Shimazu, ... PloS one 11 (3), e0151511, 2016 | 240 | 2016 |
| FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis K Tsuchiya, J Tanaka, Y Shuiqing, CL Welch, RA DePinho, I Tabas, ... Cell metabolism 15 (3), 372-381, 2012 | 188 | 2012 |
| Canagliflozin, an SGLT2 inhibitor, attenuates the development of hepatocellular carcinoma in a mouse model of human NASH K Shiba, K Tsuchiya, C Komiya, Y Miyachi, K Mori, N Shimazu, ... Scientific Reports 5 (8), 2362, 2018 | 151 | 2018 |
| Aldosterone induces angiotensin converting enzyme gene expression via a JAK2-dependent pathway in rat endothelial cells T Sugiyama, T Yoshimoto, K Tsuchiya, N Gochou, Y Hirono, T Tateno, ... Endocrinology 146 (9), 3900-3906, 2005 | 126 | 2005 |
| FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures R Bouchi, KS Foo, H Hua, K Tsuchiya, Y Ohmura, PR Sandoval, ... Nature communications 5 (1), 4242, 2014 | 118 | 2014 |
| Deficiency of ATP-binding cassette transporters A1 and G1 in endothelial cells accelerates atherosclerosis in mice M Westerterp, K Tsuchiya, IW Tattersall, P Fotakis, AE Bochem, ... Arteriosclerosis, Thrombosis, and Vascular Biology 36 (7), 1328-1337, 2016 | 110 | 2016 |
| Clinicopathological features of primary aldosteronism associated with subclinical Cushing’s syndrome K Hiraishi, T Yoshimoto, K Tsuchiya, I Minami, M Doi, H Izumiyama, ... Endocrine journal 58 (7), 543-551, 2011 | 110 | 2011 |
| Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice K Tsuchiya, H Sakai, N Suzuki, F Iwashima, T Yoshimoto, M Shichiri, ... Endocrinology 148 (10), 4548-4556, 2007 | 100 | 2007 |
| Angiotensin II induces monocyte chemoattractant protein-1 expression via a nuclear factor-κB-dependent pathway in rat preadipocytes K Tsuchiya, T Yoshimoto, Y Hirono, T Tateno, T Sugiyama, Y Hirata American Journal of Physiology-Endocrinology And Metabolism 291 (4), E771-E778, 2006 | 89 | 2006 |
| Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice K Tsuchiya, M Westerterp, AJ Murphy, V Subramanian, A Ferrante, ... Circulation research 112 (7), 992-1003, 2013 | 74 | 2013 |
| Endothelial dysfunction is related to aldosterone excess and raised blood pressure K Tsuchiya, T Yoshimoto, Y Hirata Endocrine journal 56 (4), 553-559, 2009 | 74 | 2009 |
| Endothelial dysfunction aassociated with hypercortisolism is reversible in Cushing’s syndrome I Akaza, T Yoshimoto, K Tsuchiya, Y Hirata Endocrine journal 57 (3), 245-252, 2010 | 69 | 2010 |
| Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis C Komiya, M Tanaka, K Tsuchiya, N Shimazu, K Mori, S Furuke, Y Miyachi, ... Scientific reports 7 (1), 44754, 2017 | 62 | 2017 |
| Roles for cell-cell adhesion and contact in obesity-induced hepatic myeloid cell accumulation and glucose intolerance Y Miyachi, K Tsuchiya, C Komiya, K Shiba, N Shimazu, S Yamaguchi, ... Cell reports 18 (11), 2766-2779, 2017 | 62 | 2017 |
| Forkhead box class O family member proteins: The biology and pathophysiological roles in diabetes K Tsuchiya, Y Ogawa Journal of diabetes investigation 8 (6), 726-734, 2017 | 58 | 2017 |
| Advanced endothelial dysfunction in diabetic patients with multiple risk factors; importance of insulin resistance K Tsuchiya, C Nakayama, F Iwashima, H Sakai, H Izumiyama, M Doi, ... Journal of atherosclerosis and thrombosis 14 (6), 303-309, 2007 | 52 | 2007 |
| A reduced M1-like/M2-like ratio of macrophages in healthy adipose tissue expansion during SGLT2 inhibition Y Miyachi, K Tsuchiya, K Shiba, K Mori, C Komiya, N Ogasawara, ... Scientific reports 8 (1), 16113, 2018 | 50 | 2018 |
| Improvement of endothelial function in patients with hypertension and type 2 diabetes after treatment with telmisartan T Wago, T Yoshimoto, I Akaza, K Tsuchiya, H Izumiyama, Y Hirata Hypertension Research 33 (8), 796-801, 2010 | 50 | 2010 |
| Late-night salivary cortisol as a screening test for the diagnosis of Cushing's syndrome in Japan M Doi, N Sekizawa, Y Tani, K Tsuchiya, R Kouyama, T Tateno, ... Endocrine Journal 55 (1), 121-126, 2008 | 49 | 2008 |
| Integration of transcriptome and methylome analysis of aldosterone-producing adenomas M Murakami, T Yoshimoto, K Nakabayashi, K Tsuchiya, I Minami, ... European Journal of Endocrinology 173 (2), 185-195, 2015 | 47 | 2015 |
Alan R TallMedicine, Columbia UniversityVerified email at cumc.columbia.edu
