Total synthesis of a functional designer eukaryotic chromosome N Annaluru, H Muller, LA Mitchell, S Ramalingam, G Stracquadanio, ... science 344 (6179), 55-58, 2014 | 650 | 2014 |
TH1 signatures are present in the lower airways of children with severe asthma, regardless of allergic status JA Wisniewski, LM Muehling, JD Eccles, BJ Capaldo, R Agrawal, ... Journal of Allergy and Clinical Immunology 141 (6), 2048-2060. e13, 2018 | 107 | 2018 |
Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL KD Jayappa, CA Portell, VL Gordon, BJ Capaldo, S Bekiranov, ... Blood advances 1 (14), 933-946, 2017 | 92 | 2017 |
Nascent prostate cancer heterogeneity drives evolution and resistance to intense hormonal therapy S Wilkinson, H Ye, F Karzai, SA Harmon, NT Terrigino, DJ VanderWeele, ... European urology 80 (6), 746-757, 2021 | 53 | 2021 |
Human TH1 and TH2 cells targeting rhinovirus and allergen coordinately promote allergic asthma LM Muehling, PW Heymann, PW Wright, JD Eccles, R Agrawal, ... Journal of Allergy and Clinical Immunology 146 (3), 555-570, 2020 | 41 | 2020 |
Targeting the PI3K/AKT pathway overcomes enzalutamide resistance by inhibiting induction of the glucocorticoid receptor R Adelaiye-Ogala, BE Gryder, YTM Nguyen, AN Alilin, AR Grayson, ... Molecular cancer therapeutics 19 (7), 1436-1447, 2020 | 40 | 2020 |
Synthetic lethal screening with small-molecule inhibitors provides a pathway to rational combination therapies for melanoma DG Roller, M Axelrod, BJ Capaldo, K Jensen, A Mackey, MJ Weber, ... Molecular cancer therapeutics 11 (11), 2505-2515, 2012 | 40 | 2012 |
Synergistic cytotoxicity of ibrutinib and the BCL2 antagonist, ABT-199 (GDC-0199) in mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL): molecular analysis … CA Portell, M Axelrod, LK Brett, VL Gordon, B Capaldo, JC Xing, ... Blood 124 (21), 509, 2014 | 34 | 2014 |
Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas DG Roller, B Capaldo, S Bekiranov, AJ Mackey, MR Conaway, ... Oncotarget 7 (3), 2734, 2016 | 25 | 2016 |
MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity NC Whitlock, SY Trostel, S Wilkinson, NT Terrigino, ST Hennigan, R Lake, ... Oncogene 39 (34), 5663-5674, 2020 | 18 | 2020 |
RUNX3 levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance P Balogh, ER Adelman, JV Pluvinage, BJ Capaldo, KC Freeman, S Singh, ... Haematologica 105 (4), 905, 2020 | 16 | 2020 |
Systems analysis of adaptive responses to MAP kinase pathway blockade in BRAF mutant melanoma BJ Capaldo, D Roller, MJ Axelrod, AF Koeppel, EF Petricoin, ... PLoS One 10 (9), e0138210, 2015 | 15 | 2015 |
Cardiac resynchronization therapy reduces expression of inflammation-promoting genes related to interleukin-1β in heart failure K Bilchick, H Kothari, A Narayan, J Garmey, A Omar, B Capaldo, ... Cardiovascular Research 116 (7), 1311-1322, 2020 | 14 | 2020 |
Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma MM Melssen, W Olson, NA Wages, BJ Capaldo, IS Mauldin, ... Oncoimmunology 7 (10), e1490855, 2018 | 14 | 2018 |
Identification of a new target of miR-16, Vacuolar Protein Sorting 4a N Adhikari, W Guan, B Capaldo, AJ Mackey, M Carlson, S Ramakrishnan, ... PloS one 9 (7), e101509, 2014 | 14 | 2014 |
An integrated framework using high‐dimensional mass cytometry and fluorescent flow cytometry identifies discrete B cell subsets in patients with red meat allergy KM Cox, SP Commins, BJ Capaldo, LJ Workman, TAE Platts‐Mills, ... Clinical & Experimental Allergy 49 (5), 615-625, 2019 | 11 | 2019 |
Synergistic apoptosis in head and neck squamous cell carcinoma cells by co‐inhibition of insulin‐like growth factor‐1 receptor signaling and compensatory signaling pathways MJ Axelrod, RE Mendez, A Khalil, SS Leimgruber, ER Sharlow, ... Head & neck 37 (12), 1722-1732, 2015 | 9 | 2015 |
Metastatic castration-resistant prostate cancer remains dependent on oncogenic drivers found in primary tumors DJ Einstein, S Arai, C Calagua, F Xie, O Voznesensky, BJ Capaldo, ... JCO Precision Oncology 5, 1514-1522, 2021 | 8 | 2021 |
Implementation of mass cytometry as a tool for mechanism of action studies in inflammatory bowel disease CJ Tyler, T Pérez-Jeldres, E Ehinger, B Capaldo, T Karuppuchamy, ... Inflammatory bowel diseases 24 (11), 2366-2376, 2018 | 7 | 2018 |
Progression of prostate cancer reprograms MYC-mediated lipid metabolism via lysine methyltransferase 2A NC Whitlock, ME White, BJ Capaldo, AT Ku, S Agarwal, L Fang, ... Discover Oncology 13 (1), 97, 2022 | 3 | 2022 |