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Brian J. Capaldo
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Total synthesis of a functional designer eukaryotic chromosome
N Annaluru, H Muller, LA Mitchell, S Ramalingam, G Stracquadanio, ...
science 344 (6179), 55-58, 2014
6502014
TH1 signatures are present in the lower airways of children with severe asthma, regardless of allergic status
JA Wisniewski, LM Muehling, JD Eccles, BJ Capaldo, R Agrawal, ...
Journal of Allergy and Clinical Immunology 141 (6), 2048-2060. e13, 2018
1072018
Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL
KD Jayappa, CA Portell, VL Gordon, BJ Capaldo, S Bekiranov, ...
Blood advances 1 (14), 933-946, 2017
922017
Nascent prostate cancer heterogeneity drives evolution and resistance to intense hormonal therapy
S Wilkinson, H Ye, F Karzai, SA Harmon, NT Terrigino, DJ VanderWeele, ...
European urology 80 (6), 746-757, 2021
532021
Human TH1 and TH2 cells targeting rhinovirus and allergen coordinately promote allergic asthma
LM Muehling, PW Heymann, PW Wright, JD Eccles, R Agrawal, ...
Journal of Allergy and Clinical Immunology 146 (3), 555-570, 2020
412020
Targeting the PI3K/AKT pathway overcomes enzalutamide resistance by inhibiting induction of the glucocorticoid receptor
R Adelaiye-Ogala, BE Gryder, YTM Nguyen, AN Alilin, AR Grayson, ...
Molecular cancer therapeutics 19 (7), 1436-1447, 2020
402020
Synthetic lethal screening with small-molecule inhibitors provides a pathway to rational combination therapies for melanoma
DG Roller, M Axelrod, BJ Capaldo, K Jensen, A Mackey, MJ Weber, ...
Molecular cancer therapeutics 11 (11), 2505-2515, 2012
402012
Synergistic cytotoxicity of ibrutinib and the BCL2 antagonist, ABT-199 (GDC-0199) in mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL): molecular analysis …
CA Portell, M Axelrod, LK Brett, VL Gordon, B Capaldo, JC Xing, ...
Blood 124 (21), 509, 2014
342014
Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas
DG Roller, B Capaldo, S Bekiranov, AJ Mackey, MR Conaway, ...
Oncotarget 7 (3), 2734, 2016
252016
MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity
NC Whitlock, SY Trostel, S Wilkinson, NT Terrigino, ST Hennigan, R Lake, ...
Oncogene 39 (34), 5663-5674, 2020
182020
RUNX3 levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance
P Balogh, ER Adelman, JV Pluvinage, BJ Capaldo, KC Freeman, S Singh, ...
Haematologica 105 (4), 905, 2020
162020
Systems analysis of adaptive responses to MAP kinase pathway blockade in BRAF mutant melanoma
BJ Capaldo, D Roller, MJ Axelrod, AF Koeppel, EF Petricoin, ...
PLoS One 10 (9), e0138210, 2015
152015
Cardiac resynchronization therapy reduces expression of inflammation-promoting genes related to interleukin-1β in heart failure
K Bilchick, H Kothari, A Narayan, J Garmey, A Omar, B Capaldo, ...
Cardiovascular Research 116 (7), 1311-1322, 2020
142020
Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma
MM Melssen, W Olson, NA Wages, BJ Capaldo, IS Mauldin, ...
Oncoimmunology 7 (10), e1490855, 2018
142018
Identification of a new target of miR-16, Vacuolar Protein Sorting 4a
N Adhikari, W Guan, B Capaldo, AJ Mackey, M Carlson, S Ramakrishnan, ...
PloS one 9 (7), e101509, 2014
142014
An integrated framework using high‐dimensional mass cytometry and fluorescent flow cytometry identifies discrete B cell subsets in patients with red meat allergy
KM Cox, SP Commins, BJ Capaldo, LJ Workman, TAE Platts‐Mills, ...
Clinical & Experimental Allergy 49 (5), 615-625, 2019
112019
Synergistic apoptosis in head and neck squamous cell carcinoma cells by co‐inhibition of insulin‐like growth factor‐1 receptor signaling and compensatory signaling pathways
MJ Axelrod, RE Mendez, A Khalil, SS Leimgruber, ER Sharlow, ...
Head & neck 37 (12), 1722-1732, 2015
92015
Metastatic castration-resistant prostate cancer remains dependent on oncogenic drivers found in primary tumors
DJ Einstein, S Arai, C Calagua, F Xie, O Voznesensky, BJ Capaldo, ...
JCO Precision Oncology 5, 1514-1522, 2021
82021
Implementation of mass cytometry as a tool for mechanism of action studies in inflammatory bowel disease
CJ Tyler, T Pérez-Jeldres, E Ehinger, B Capaldo, T Karuppuchamy, ...
Inflammatory bowel diseases 24 (11), 2366-2376, 2018
72018
Progression of prostate cancer reprograms MYC-mediated lipid metabolism via lysine methyltransferase 2A
NC Whitlock, ME White, BJ Capaldo, AT Ku, S Agarwal, L Fang, ...
Discover Oncology 13 (1), 97, 2022
32022
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