Glutamate receptors as therapeutic targets for Parkinson's disease KA Johnson, PJ Conn, CM Niswender CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2009 | 314 | 2009 |
Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4 CM Niswender, KA Johnson, CD Weaver, CK Jones, Z Xiang, Q Luo, ... Molecular pharmacology 74 (5), 1345-1358, 2008 | 232 | 2008 |
Parallel, but dissociable, processing in discrete corticostriatal inputs encodes skill learning DA Kupferschmidt, K Juczewski, G Cui, KA Johnson, DM Lovinger Neuron 96 (2), 476-489. e5, 2017 | 180 | 2017 |
An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission JK Shirey, Z Xiang, D Orton, AE Brady, KA Johnson, R Williams, JE Ayala, ... Nature Chemical Biology 4 (1), nchembio. 2007.55, 2007 | 176 | 2007 |
A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors CM Niswender, KA Johnson, Q Luo, JE Ayala, C Kim, PJ Conn, ... Molecular pharmacology 73 (4), 1213-1224, 2008 | 132 | 2008 |
Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS S Yin, MJ Noetzel, KA Johnson, R Zamorano, N Jalan-Sakrikar, ... Journal of Neuroscience 34 (1), 79-94, 2014 | 131 | 2014 |
Biased mGlu5-positive allosteric modulators provide in vivo efficacy without potentiating mGlu5 modulation of NMDAR currents JM Rook, Z Xiang, X Lv, A Ghoshal, JW Dickerson, TM Bridges, ... Neuron 86 (4), 1029-1040, 2015 | 128 | 2015 |
Endocannabinoid Actions on Cortical Terminals Orchestrate Local Modulation of Dopamine Release in the Nucleus Accumbens Y Mateo, KA Johnson, DP Covey, BK Atwood, HL Wang, S Zhang, ... Neuron 96 (5), 1112-1126. e5, 2017 | 107 | 2017 |
Context-dependent pharmacology exhibited by negative allosteric modulators of metabotropic glutamate receptor 7 CM Niswender, KA Johnson, NR Miller, JE Ayala, Q Luo, R Williams, ... Molecular pharmacology 77 (3), 459-468, 2010 | 90 | 2010 |
Presynaptic G protein-coupled receptors: gatekeepers of addiction? KA Johnson, DM Lovinger Frontiers in cellular neuroscience 10, 264, 2016 | 53 | 2016 |
Metabotropic glutamate receptor 2 inhibits thalamically-driven glutamate and dopamine release in the dorsal striatum KA Johnson, Y Mateo, DM Lovinger Neuropharmacology 117, 114-123, 2017 | 45 | 2017 |
Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4) R Williams, KA Johnson, PR Gentry, CM Niswender, CD Weaver, ... Bioorganic & medicinal chemistry letters 19 (17), 4967-4970, 2009 | 38 | 2009 |
The metabotropic glutamate receptor 8 agonist (S)-3, 4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease KA Johnson, CK Jones, MN Tantawy, M Bubser, M Marvanova, MS Ansari, ... Neuropharmacology 66, 187-195, 2013 | 33 | 2013 |
Local modulation by presynaptic receptors controls neuronal communication and behaviour DM Lovinger, Y Mateo, KA Johnson, SA Engi, M Antonazzo, JF Cheer Nature Reviews Neuroscience 23 (4), 191-203, 2022 | 32 | 2022 |
Activation of group II metabotropic glutamate receptors induces long-term depression of excitatory synaptic transmission in the substantia nigra pars reticulata KA Johnson, CM Niswender, PJ Conn, Z Xiang Neuroscience letters 504 (2), 102-106, 2011 | 32 | 2011 |
Operant self-stimulation of thalamic terminals in the dorsomedial striatum is constrained by metabotropic glutamate receptor 2 KA Johnson, L Voyvodic, GC Loewinger, Y Mateo, DM Lovinger Neuropsychopharmacology 45 (9), 1454-1462, 2020 | 20 | 2020 |
Age-dependent impairment of metabotropic glutamate receptor 2-dependent long-term depression in the mouse striatum by chronic ethanol exposure KA Johnson, DJ Liput, GE Homanics, DM Lovinger Alcohol 82, 11-21, 2020 | 14 | 2020 |
Allosteric modulation of metabotropic glutamate receptors in alcohol use disorder: Insights from preclinical investigations KA Johnson, DM Lovinger Advances in Pharmacology 88, 193-232, 2020 | 12 | 2020 |
Impact of isoflurane anesthesia on D2 receptor occupancy by [18F] fallypride measured by microPET with a modified Logan plot MN Tantawy, TE Peterson, CK Jones, K Johnson, JM Rook, PJ Conn, ... Synapse 65 (11), 1173-1180, 2011 | 11 | 2011 |
Active zone proteins RIM1αβ are required for normal corticostriatal transmission and action control DA Kupferschmidt, SM Augustin, KA Johnson, DM Lovinger Journal of Neuroscience 39 (8), 1457-1470, 2019 | 10 | 2019 |