Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans. CD Link Proceedings of the National Academy of Sciences 92 (20), 9368-9372, 1995 | 795 | 1995 |
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity YJ Zhang, YF Xu, C Cook, TF Gendron, P Roettges, CD Link, WL Lin, ... Proceedings of the National Academy of Sciences 106 (18), 7607-7612, 2009 | 668 | 2009 |
Oxidative stress precedes fibrillar deposition of Alzheimer’s disease amyloid β-peptide (1–42) in a transgenic Caenorhabditis elegans model J Drake, CD Link, DA Butterfield Neurobiology of aging 24 (3), 415-420, 2003 | 464 | 2003 |
Amyloid-β-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans Y Wu, Z Wu, P Butko, Y Christen, MP Lambert, WL Klein, CD Link, Y Luo Journal of Neuroscience 26 (50), 13102-13113, 2006 | 456 | 2006 |
A global analysis of Caenorhabditis elegans operons T Blumenthal, D Evans, CD Link, A Guffanti, D Lawson, J Thierry-Mieg, ... Nature 417 (6891), 851-854, 2002 | 446 | 2002 |
In vitro and in vivo oxidative stress associated with Alzheimer's amyloid beta-peptide (1-42) SM Yatin, S Varadarajan, CD Link, DA Butterfield Neurobiology of aging 20 (3), 325-30; discussion 339, 1999 | 440 | 1999 |
RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome B Van Treeck, DSW Protter, T Matheny, A Khong, CD Link, R Parker Proceedings of the National Academy of Sciences 115 (11), 2734-2739, 2018 | 432 | 2018 |
Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS M Prudencio, VV Belzil, R Batra, CA Ross, TF Gendron, LJ Pregent, ... Nature neuroscience 18 (8), 1175-1182, 2015 | 378 | 2015 |
Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer’s disease model CD Link, A Taft, V Kapulkin, K Duke, S Kim, Q Fei, DE Wood, BG Sahagan Neurobiology of aging 24 (3), 397-413, 2003 | 366 | 2003 |
C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins YJ Zhang, TF Gendron, JC Grima, H Sasaguri, K Jansen-West, YF Xu, ... Nature neuroscience 19 (5), 668-677, 2016 | 317 | 2016 |
Neurotoxic effects of TDP-43 overexpression in C. elegans PEA Ash, YJ Zhang, CM Roberts, T Saldi, H Hutter, E Buratti, L Petrucelli, ... Human molecular genetics 19 (16), 3206-3218, 2010 | 283 | 2010 |
Interaction of intracellular β amyloid peptide with chaperone proteins V Fonte, WJ Kapulkin, A Taft, A Fluet, D Friedman, CD Link Proceedings of the National Academy of Sciences 99 (14), 9439-9444, 2002 | 273 | 2002 |
C. elegans models of age-associated neurodegenerative diseases: lessons from transgenic worm models of Alzheimer’s disease CD Link Experimental gerontology 41 (10), 1007-1013, 2006 | 260 | 2006 |
Utility of an improved model of amyloid-beta (Aβ1-42) toxicity in Caenorhabditis elegansfor drug screening for Alzheimer’s disease G McColl, BR Roberts, TL Pukala, VB Kenche, CM Roberts, CD Link, ... Molecular neurodegeneration 7, 1-9, 2012 | 253 | 2012 |
Direct observation of stress response in Caenorhabditis elegans using a reporter transgene CD Link, JR Cypser, CJ Johnson, TE Johnson Cell stress & chaperones 4 (4), 235, 1999 | 251 | 1999 |
A stress-responsive glutathione S-transferase confers resistance to oxidative stress in Caenorhabditis elegans B Leiers, A Kampkötter, CG Grevelding, CD Link, TE Johnson, ... Free Radical Biology and Medicine 34 (11), 1405-1415, 2003 | 226 | 2003 |
Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease TE Johnson, S Henderson, S Murakami, E De Castro, SH de Castro, ... Journal of inherited metabolic disease 25, 197-206, 2002 | 224 | 2002 |
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity YJ Zhang, L Guo, PK Gonzales, TF Gendron, Y Wu, K Jansen-West, ... Science 363 (6428), eaav2606, 2019 | 205 | 2019 |
Identification of a novel cis-regulatory element involved in the heat shock response in Caenorhabditis elegans using microarray gene expression and computational methods D GuhaThakurta, L Palomar, GD Stormo, P Tedesco, TE Johnson, ... Genome research 12 (5), 701-712, 2002 | 205 | 2002 |
In vivo aggregation of β‐Amyloid peptide variants DS Fay, A Fluet, CJ Johnson, CD Link Journal of neurochemistry 71 (4), 1616-1625, 1998 | 200 | 1998 |