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Lin Xiao, PhD
Lin Xiao, PhD
Alexion Pharmaceuticals
Verified email at alexion.com
Title
Cited by
Cited by
Year
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma
LD Gamble, S Purgato, J Murray, L Xiao, DMT Yu, KM Hanssen, ...
Science Translational Medicine 11 (477), eaau1099, 2019
1072019
The role of hypoxia-inducible factor 1α in determining the properties of castrate-resistant prostate cancers
WKB Ranasinghe, L Xiao, S Kovac, M Chang, C Michiels, D Bolton, ...
PloS one 8 (1), e54251, 2013
922013
Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β–induced Serpine1
JV McCann, L Xiao, DJ Kim, OF Khan, PS Kowalski, DG Anderson, ...
The Journal of clinical investigation 129 (4), 1654-1670, 2019
762019
Vascular channels formed by subpopulations of PECAM1+ melanoma cells
JM Dunleavey, L Xiao, J Thompson, MM Kim, JM Shields, SE Shelton, ...
Nature communications 5 (1), 5200, 2014
752014
Fine‐tuning vascular fate during endothelial–mesenchymal transition
L Xiao, AC Dudley
The Journal of pathology 241 (1), 25-35, 2017
742017
Tumor endothelial cells with distinct patterns of TGFβ-driven endothelial-to-mesenchymal transition
L Xiao, DJ Kim, CL Davis, JV McCann, JM Dunleavey, AK Vanderlinden, ...
Cancer research 75 (7), 1244-1254, 2015
712015
Variants of rab GTPase–effector binding protein-2 cause variation in the collateral circulation and severity of stroke
JL Lucitti, R Sealock, BK Buckley, H Zhang, L Xiao, AC Dudley, JE Faber
Stroke 47 (12), 3022-3031, 2016
652016
Suppression of TGFβ-mediated conversion of endothelial cells and fibroblasts into cancer associated (myo) fibroblasts via HDAC inhibition
DJ Kim, JM Dunleavey, L Xiao, DW Ollila, MA Troester, CA Otey, W Li, ...
British Journal of Cancer 118 (10), 1359-1368, 2018
532018
Protective effect of zinc preconditioning against renal ischemia reperfusion injury is dose dependent
K Rao, K Sethi, J Ischia, L Gibson, L Galea, L Xiao, M Yim, M Chang, ...
PLoS One 12 (7), e0180028, 2017
472017
A mussel-inspired strategy for CNT/carbon fiber reinforced epoxy composite by hierarchical surface modification
N Xu, Y Li, T Zheng, L Xiao, Y Liu, S Chen, D Zhang
Colloids and Surfaces A: Physicochemical and Engineering Aspects 635, 128085, 2022
422022
Gastrin increases its own synthesis in gastrointestinal cancer cells via the CCK2 receptor
S Kovac, L Xiao, A Shulkes, O Patel, GS Baldwin
FEBS letters 584 (21), 4413-4418, 2010
352010
Identification of a stable molecular signature in mammary tumor endothelial cells that persists in vitro
L Xiao, JC Harrell, CM Perou, AC Dudley
Angiogenesis 17, 511-518, 2014
282014
Induction of gastrin expression in gastrointestinal cells by hypoxia or cobalt is independent of hypoxia-inducible factor (HIF)
L Xiao, S Kovac, M Chang, A Shulkes, GS Baldwin, O Patel
Endocrinology 153 (7), 3006-3016, 2012
212012
Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma
L Xiao, K Somers, J Murray, R Pandher, M Karsa, E Ronca, A Bongers, ...
Clinical Cancer Research 27 (15), 4338-4352, 2021
172021
Isolation and Culture Expansion of Tumor-specific Endothelial Cells
L Xiao, JV McCann, AC Dudley
Journal of Visualized Experiments (JoVE), 2015
142015
Zinc ions upregulate the hormone gastrin via an E-box motif in the proximal gastrin promoter
L Xiao, S Kovac, M Chang, A Shulkes, GS Baldwin, O Patel
J Mol Endocrinol 52 (1), 29-42, 2014
142014
Immunometabolism: a ‘hot’switch for ‘cold’pediatric solid tumors
L Xiao, H Yeung, M Haber, MD Norris, K Somers
Trends in Cancer 7 (8), 751-777, 2021
102021
Zinc ions mediate gastrin expression, proliferation, and migration downstream of the cholecystokinin-2 receptor
M Chang, L Xiao, A Shulkes, GS Baldwin, O Patel
Endocrinology 157 (12), 4706-4719, 2016
102016
The combination of curaxin CBL0137 and histone deacetylase inhibitor panobinostat delays KMT2A-rearranged leukemia progression
L Xiao, M Karsa, E Ronca, A Bongers, A Kosciolek, A El-Ayoubi, ...
Frontiers in Oncology 12, 863329, 2022
92022
Curing behaviors and thermomechanical properties of novolac cyanate–polyhedral oligomeric silsesquioxane copolymers
X Li, W Huang, Y Sui, G Wang, L Xiao, D Zhang
Composites Communications 28, 100932, 2021
52021
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