Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA KS Winther, K Gerdes Proceedings of the National Academy of Sciences 108 (18), 7403-7407, 2011 | 300 | 2011 |
VapC20 of Mycobacterium tuberculosis cleaves the Sarcin–Ricin loop of 23S rRNA KS Winther, DE Brodersen, AK Brown, K Gerdes Nature communications 4 (1), 2796, 2013 | 135 | 2013 |
Ribosome hibernation T Prossliner, K Skovbo Winther, MA Sørensen, K Gerdes Annual review of genetics 52, 321-348, 2018 | 129 | 2018 |
VapCs of Mycobacterium tuberculosis cleave RNAs essential for translation K Winther, JJ Tree, D Tollervey, K Gerdes Nucleic acids research 44 (20), 9860-9871, 2016 | 124 | 2016 |
Activation of the stringent response by loading of RelA-tRNA complexes at the ribosomal A-site KS Winther, M Roghanian, K Gerdes Molecular cell 70 (1), 95-105. e4, 2018 | 101 | 2018 |
Regulation of Enteric vapBC Transcription: Induction by VapC Toxin Dimer-Breaking KS Winther, K Gerdes Nucleic acids research 40 (10), 4347-4357, 2012 | 93 | 2012 |
Crystal Structure of the VapBC Toxin–Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly C Dienemann, A Bøggild, KS Winther, K Gerdes, DE Brodersen Journal of molecular biology 414 (5), 713-722, 2011 | 89 | 2011 |
Ectopic production of VapCs from Enterobacteria inhibits translation and trans‐activates YoeB mRNA interferase KS Winther, K Gerdes Molecular microbiology 72 (4), 918-930, 2009 | 81 | 2009 |
The RES domain toxins of RES‐Xre toxin‐antitoxin modules induce cell stasis by degrading NAD+ RB Skjerning, M Senissar, KS Winther, K Gerdes, DE Brodersen Molecular microbiology 111 (1), 221-236, 2019 | 47 | 2019 |
Fatty acid starvation activates RelA by depleting lysine precursor pyruvate AK Sinha, KS Winther, M Roghanian, K Gerdes Molecular Microbiology 112 (4), 1339-1349, 2019 | 32 | 2019 |
RNA decay by messenger RNA interferases M Christensen‐Dalsgaard, M Overgaard, KS Winther, K Gerdes Methods in enzymology 447, 521-535, 2008 | 32 | 2008 |
Hibernation factors directly block ribonucleases from entering the ribosome in response to starvation T Prossliner, K Gerdes, MA Sørensen, KS Winther Nucleic Acids Research 49 (4), 2226-2239, 2021 | 27 | 2021 |
Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding KL Bendtsen, K Xu, M Luckmann, KS Winther, SA Shah, CNS Pedersen, ... Nucleic acids research 45 (5), 2875-2886, 2017 | 21 | 2017 |
The RelA hydrolase domain acts as a molecular switch for (p) ppGpp synthesis AK Sinha, KS Winther Communications Biology 4 (1), 434, 2021 | 20 | 2021 |
Maintenance of the Shigella sonnei virulence plasmid is dependent on its repertoire and amino acid sequence of toxin-antitoxin systems JE Martyn, G Pilla, S Hollingshead, KS Winther, S Lea, G McVicker, ... Journal of Bacteriology 204 (3), e00519-21, 2022 | 9 | 2022 |
Polyamines are required for tRNA anticodon modification in Escherichia coli KS Winther, MA Sørensen, SL Svenningsen Journal of Molecular Biology 433 (15), 167073, 2021 | 9 | 2021 |
Protein expression, crystallization and preliminary X-ray crystallographic analysis of the isolated Shigella flexneri VapC toxin K Xu, E Dedic, P Cob-Cantal, C Dienemann, A Bøggild, KS Winther, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 7 | 2013 |
VapC20 of Mycobacterium tuberculosis cleaves the sarcin-ricin loop of 23S rRNA. Nat Commun 4: 2796 KS Winther, DE Brodersen, AK Brown, K Gerdes | 6 | 2013 |
Corrigendum to article ‘Hibernation factors directly block ribonucleases from entering the ribosome in response to starvation’ T Prossliner, K Gerdes, MA Sørensen, KS Winther Nucleic Acids Research 49 (6), 3599, 2021 | 1 | 2021 |
The RelA hydrolase domain: a molecular switch for (p) ppGpp synthesis AK Sinha, KS Winther bioRxiv, 2020.12. 14.421628, 2020 | | 2020 |