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Shinya Tasaki
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A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease
S Mostafavi, C Gaiteri, SE Sullivan, CC White, S Tasaki, J Xu, M Taga, ...
Nature neuroscience 21 (6), 811-819, 2018
4002018
Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission
S Tasaki, K Suzuki, Y Kassai, M Takeshita, A Murota, Y Kondo, T Ando, ...
Nature communications 9 (1), 2755, 2018
1552018
Multiomic disease signatures converge to cytotoxic CD8 T cells in primary Sjögren’s syndrome
S Tasaki, K Suzuki, A Nishikawa, Y Kassai, M Takiguchi, R Kurisu, ...
Annals of the Rheumatic Diseases 76 (8), 1458-1466, 2017
1012017
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors
VN Lagomarsino, RV Pearse, L Liu, YC Hsieh, MA Fernandez, EA Vinton, ...
Neuron 109 (21), 3402-3420. e9, 2021
812021
Cortical proteins associated with cognitive resilience in community-dwelling older persons
L Yu, S Tasaki, JA Schneider, K Arfanakis, DM Duong, AP Wingo, ...
JAMA psychiatry 77 (11), 1172-1180, 2020
722020
Temporal perturbation of tyrosine phosphoproteome dynamics reveals the system-wide regulatory networks
M Oyama, H Kozuka-Hata, S Tasaki, K Semba, S Hattori, S Sugano, ...
Molecular & Cellular Proteomics 8 (2), 226-231, 2009
652009
Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer’s dementia
K Kaneshwaran, M Olah, S Tasaki, L Yu, EM Bradshaw, JA Schneider, ...
Science advances 5 (12), eaax7331, 2019
632019
Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts
ASP Lim, C Gaiteri, L Yu, S Sohail, W Swardfager, S Tasaki, JA Schneider, ...
PLoS medicine 15 (9), e1002647, 2018
612018
CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor
T Funnell, S Tasaki, A Oloumi, S Araki, E Kong, D Yap, Y Nakayama, ...
Nature Communications 8 (1), 7, 2017
522017
The molecular and neuropathological consequences of genetic risk for Alzheimer's dementia
S Tasaki, C Gaiteri, S Mostafavi, PL De Jager, DA Bennett
Frontiers in neuroscience 12, 699, 2018
482018
Modeling and estimation of dynamic EGFR pathway by data assimilation approach using time series proteomic data
S Tasaki, M Nagasaki, M Oyama, H Hata, K Ueno, R Yoshida, T Higuchi, ...
Genome Informatics 17 (2), 226-238, 2006
402006
Deep learning decodes the principles of differential gene expression
S Tasaki, C Gaiteri, S Mostafavi, Y Wang
Nature Machine Intelligence 2 (7), 376-386, 2020
372020
Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks
S Tasaki, J Xu, DR Avey, L Johnson, VA Petyuk, RJ Dawe, DA Bennett, ...
Nature Communications 13 (1), 655, 2022
332022
Failure to confirm CNVs as of aetiological significance in twin pairs discordant for schizophrenia
S Ono, A Imamura, S Tasaki, N Kurotaki, H Ozawa, K Yoshiura, Y Okazaki
Twin Research and Human Genetics 13 (5), 455-460, 2010
322010
Identification of novel genes associated with dysregulation of B cells in patients with primary Sjögren’s syndrome
J Inamo, K Suzuki, M Takeshita, Y Kassai, M Takiguchi, R Kurisu, ...
Arthritis Research & Therapy 22, 1-11, 2020
312020
Association of cortical β-amyloid protein in the absence of insoluble deposits with Alzheimer disease
L Yu, VA Petyuk, S Tasaki, PA Boyle, C Gaiteri, JA Schneider, ...
JAMA neurology 76 (7), 818-826, 2019
302019
Transgenic mice overexpressing miR-137 in the brain show schizophrenia-associated behavioral deficits and transcriptome profiles
Y Arakawa, K Yokoyama, S Tasaki, J Kato, K Nakashima, M Takeyama, ...
PloS one 14 (7), e0220389, 2019
292019
Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling
S Tasaki, M Nagasaki, H Kozuka-Hata, K Semba, N Gotoh, S Hattori, ...
PloS one 5 (11), e13926, 2010
282010
Identification of novel schizophrenia loci by homozygosity mapping using DNA microarray analysis
N Kurotaki, S Tasaki, H Mishima, S Ono, A Imamura, T Kikuchi, N Nishida, ...
PLoS One 6 (5), e20589, 2011
252011
Bayesian network reconstruction using systems genetics data: comparison of MCMC methods
S Tasaki, B Sauerwine, B Hoff, H Toyoshiba, C Gaiteri, E Chaibub Neto
Genetics 199 (4), 973-989, 2015
232015
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Articles 1–20