A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease S Mostafavi, C Gaiteri, SE Sullivan, CC White, S Tasaki, J Xu, M Taga, ... Nature neuroscience 21 (6), 811-819, 2018 | 400 | 2018 |
Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission S Tasaki, K Suzuki, Y Kassai, M Takeshita, A Murota, Y Kondo, T Ando, ... Nature communications 9 (1), 2755, 2018 | 155 | 2018 |
Multiomic disease signatures converge to cytotoxic CD8 T cells in primary Sjögren’s syndrome S Tasaki, K Suzuki, A Nishikawa, Y Kassai, M Takiguchi, R Kurisu, ... Annals of the Rheumatic Diseases 76 (8), 1458-1466, 2017 | 101 | 2017 |
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors VN Lagomarsino, RV Pearse, L Liu, YC Hsieh, MA Fernandez, EA Vinton, ... Neuron 109 (21), 3402-3420. e9, 2021 | 81 | 2021 |
Cortical proteins associated with cognitive resilience in community-dwelling older persons L Yu, S Tasaki, JA Schneider, K Arfanakis, DM Duong, AP Wingo, ... JAMA psychiatry 77 (11), 1172-1180, 2020 | 72 | 2020 |
Temporal perturbation of tyrosine phosphoproteome dynamics reveals the system-wide regulatory networks M Oyama, H Kozuka-Hata, S Tasaki, K Semba, S Hattori, S Sugano, ... Molecular & Cellular Proteomics 8 (2), 226-231, 2009 | 65 | 2009 |
Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer’s dementia K Kaneshwaran, M Olah, S Tasaki, L Yu, EM Bradshaw, JA Schneider, ... Science advances 5 (12), eaax7331, 2019 | 63 | 2019 |
Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts ASP Lim, C Gaiteri, L Yu, S Sohail, W Swardfager, S Tasaki, JA Schneider, ... PLoS medicine 15 (9), e1002647, 2018 | 61 | 2018 |
CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor T Funnell, S Tasaki, A Oloumi, S Araki, E Kong, D Yap, Y Nakayama, ... Nature Communications 8 (1), 7, 2017 | 52 | 2017 |
The molecular and neuropathological consequences of genetic risk for Alzheimer's dementia S Tasaki, C Gaiteri, S Mostafavi, PL De Jager, DA Bennett Frontiers in neuroscience 12, 699, 2018 | 48 | 2018 |
Modeling and estimation of dynamic EGFR pathway by data assimilation approach using time series proteomic data S Tasaki, M Nagasaki, M Oyama, H Hata, K Ueno, R Yoshida, T Higuchi, ... Genome Informatics 17 (2), 226-238, 2006 | 40 | 2006 |
Deep learning decodes the principles of differential gene expression S Tasaki, C Gaiteri, S Mostafavi, Y Wang Nature Machine Intelligence 2 (7), 376-386, 2020 | 37 | 2020 |
Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks S Tasaki, J Xu, DR Avey, L Johnson, VA Petyuk, RJ Dawe, DA Bennett, ... Nature Communications 13 (1), 655, 2022 | 33 | 2022 |
Failure to confirm CNVs as of aetiological significance in twin pairs discordant for schizophrenia S Ono, A Imamura, S Tasaki, N Kurotaki, H Ozawa, K Yoshiura, Y Okazaki Twin Research and Human Genetics 13 (5), 455-460, 2010 | 32 | 2010 |
Identification of novel genes associated with dysregulation of B cells in patients with primary Sjögren’s syndrome J Inamo, K Suzuki, M Takeshita, Y Kassai, M Takiguchi, R Kurisu, ... Arthritis Research & Therapy 22, 1-11, 2020 | 31 | 2020 |
Association of cortical β-amyloid protein in the absence of insoluble deposits with Alzheimer disease L Yu, VA Petyuk, S Tasaki, PA Boyle, C Gaiteri, JA Schneider, ... JAMA neurology 76 (7), 818-826, 2019 | 30 | 2019 |
Transgenic mice overexpressing miR-137 in the brain show schizophrenia-associated behavioral deficits and transcriptome profiles Y Arakawa, K Yokoyama, S Tasaki, J Kato, K Nakashima, M Takeyama, ... PloS one 14 (7), e0220389, 2019 | 29 | 2019 |
Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling S Tasaki, M Nagasaki, H Kozuka-Hata, K Semba, N Gotoh, S Hattori, ... PloS one 5 (11), e13926, 2010 | 28 | 2010 |
Identification of novel schizophrenia loci by homozygosity mapping using DNA microarray analysis N Kurotaki, S Tasaki, H Mishima, S Ono, A Imamura, T Kikuchi, N Nishida, ... PLoS One 6 (5), e20589, 2011 | 25 | 2011 |
Bayesian network reconstruction using systems genetics data: comparison of MCMC methods S Tasaki, B Sauerwine, B Hoff, H Toyoshiba, C Gaiteri, E Chaibub Neto Genetics 199 (4), 973-989, 2015 | 23 | 2015 |