Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids. JC Rodriguez, G Gil-Gómez, FG Hegardt, D Haro Journal of Biological Chemistry 269 (29), 18767-18772, 1994 | 466 | 1994 |
Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor C Mascaró, E Acosta, JA Ortiz, PF Marrero, FG Hegardt, D Haro Journal of Biological Chemistry 273 (15), 8560-8563, 1998 | 430 | 1998 |
Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation AL De Sousa-Coelho, PF Marrero, D Haro Biochemical Journal 443 (1), 165-171, 2012 | 257 | 2012 |
FGF21 mediates the lipid metabolism response to amino acid starvation AL De Sousa-Coelho, J Relat, E Hondares, A Pérez-Martí, F Ribas, ... Journal of lipid research 54 (7), 1786-1797, 2013 | 138 | 2013 |
Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression in HepG2 cell line A Vilà-Brau, AL De Sousa-Coelho, C Mayordomo, D Haro, PF Marrero Journal of Biological Chemistry 286 (23), 20423-20430, 2011 | 136 | 2011 |
Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75 T Puig, A Vázquez-Martín, J Relat, J Pétriz, JA Menéndez, R Porta, ... Breast cancer research and treatment 109, 471-479, 2008 | 133 | 2008 |
Novel inhibitors of fatty acid synthase with anticancer activity T Puig, C Turrado, B Benhamú, H Aguilar, J Relat, S Ortega-Gutiérrez, ... Clinical Cancer Research 15 (24), 7608-7615, 2009 | 130 | 2009 |
Rat mitochondrial and cytosolic 3-hydroxy-3-methylglutaryl-CoA synthases are encoded by two different genes. J Ayte, G Gil-Gomez, D Haro, PF Marrero, FG Hegardt Proceedings of the National Academy of Sciences 87 (10), 3874-3878, 1990 | 112 | 1990 |
Ketogenic HMGCS2 Is a c-Myc target gene expressed in differentiated cells of human colonic epithelium and down-regulated in colon cancer N Camarero, C Mascaro, C Mayordomo, F Vilardell, D Haro, PF Marrero Molecular Cancer Research 4 (9), 645-653, 2006 | 100 | 2006 |
Different fatty acid metabolism effects of (−)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer J Relat, A Blancafort, G Oliveras, S Cufí, D Haro, PF Marrero, T Puig BMC cancer 12, 1-8, 2012 | 99 | 2012 |
An intronic peroxisome proliferator-activated receptor-binding sequence mediates fatty acid induction of the human carnitine palmitoyltransferase 1A L Napal, PF Marrero, D Haro Journal of molecular biology 354 (4), 751-759, 2005 | 90 | 2005 |
Cholesterol and bile acids regulate cholesterol 7 α-hydroxylase expression at the transcriptional level in culture and in transgenic mice MI Ramirez, D Karaoglu, D Haro, C Barillas, R Bashirzadeh, G Gil Molecular and cellular biology, 1994 | 89 | 1994 |
Down-regulation of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by insulin: the role of the forkhead transcription factor FKHRL1 A Nadal, PF Marrero, D Haro Biochemical Journal 366 (1), 289-297, 2002 | 82 | 2002 |
New synthetic inhibitors of fatty acid synthase with anticancer activity C Turrado, T Puig, J García-Cárceles, M Artola, B Benhamú, ... Journal of medicinal chemistry 55 (11), 5013-5023, 2012 | 79 | 2012 |
Control of human carnitine palmitoyltransferase II gene transcription by peroxisome proliferator-activated receptor through a partially conserved peroxisome proliferator … MJ Barrero, N Camarero, PF Marrero, D Haro Biochemical Journal 369 (3), 721-729, 2003 | 79 | 2003 |
Green tea catechin inhibits fatty acid synthase without stimulating carnitine palmitoyltransferase-1 or inducing weight loss in experimental animals T Puig, J Relat, PF Marrero, D Haro, J Brunet, R Colomer Anticancer research 28 (6A), 3671-3676, 2008 | 75 | 2008 |
Fibroblast growth factor 21 and the adaptive response to nutritional challenges Ú Martínez-Garza, D Torres-Oteros, A Yarritu-Gallego, PF Marrero, ... International journal of molecular sciences 20 (19), 4692, 2019 | 72 | 2019 |
Metabolic impact of flavonoids consumption in obesity: From central to peripheral V Sandoval, H Sanz-Lamora, G Arias, PF Marrero, D Haro, J Relat Nutrients 12 (8), 2393, 2020 | 62 | 2020 |
Nutritional regulation of gene expression: Carbohydrate-, fat-and amino acid-dependent modulation of transcriptional activity D Haro, PF Marrero, J Relat International journal of molecular sciences 20 (6), 1386, 2019 | 60 | 2019 |
Histone deacetylase inhibitors stimulate mitochondrial HMG‐CoA synthase gene expression via a promoter proximal Sp1 site N Camarero, A Nadal, MJ Barrero, D Haro, PF Marrero Nucleic acids research 31 (6), 1693-1703, 2003 | 60 | 2003 |