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Jean C. Dinh
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Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy
JT Brown, JR Bishop, K Sangkuhl, EL Nurmi, DJ Mueller, JC Dinh, ...
Clinical Pharmacology & Therapeutics 106 (1), 94-102, 2019
1822019
Ten years’ experience with the CYP2D6 activity score: a perspective on future investigations to improve clinical predictions for precision therapeutics
A Gaedigk, JC Dinh, H Jeong, B Prasad, JS Leeder
Journal of personalized medicine 8 (2), 15, 2018
1372018
Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo
BS Raccor, AJ Claessens, JC Dinh, JR Park, DS Hawkins, SS Thomas, ...
Drug Metabolism and Disposition 40 (1), 54-63, 2012
592012
Molecular regulation of bile acid homeostasis
S Choudhuri, CD Klaassen
Drug Metabolism and Disposition 50 (4), 425-455, 2022
282022
Characterization of atomoxetine biotransformation and implications for development of PBPK models for dose individualization in children
JC Dinh, RE Pearce, L Van Haandel, A Gaedigk, JS Leeder
Drug Metabolism and Disposition 44 (7), 1070-1079, 2016
262016
Genetic determinants of fetal opiate exposure and risk of neonatal abstinence syndrome: knowledge deficits and prospects for future research
T Lewis, J Dinh, JS Leeder
Clinical Pharmacology & Therapeutics 98 (3), 309-320, 2015
242015
Is this the end for ranitidine? NDMA presence continues to confound
JA Wagner, JC Dinh, JR Lightdale, BD Gold, JM Colombo
Clinical and Translational Science 14 (4), 1197, 2021
142021
Ontogeny of scaling factors for pediatric physiology-based pharmacokinetic modeling and simulation: microsomal protein per gram of liver
JS Leeder, JC Dinh, A Gaedigk, VS Staggs, B Prasad, RE Pearce
Drug Metabolism and Disposition 50 (1), 24-32, 2022
82022
Description of an innovative pediatric individualized therapeutics clinic: working toward precision drug therapy
TL Sandritter, JC Dinh, JA Wagner, JA Lowry
Children 6 (2), 35, 2019
62019
Impact of CYP2C:TG Haplotype on CYP2C19 Substrates Clearance In Vivo, Protein Content, and In Vitro Activity
P Zubiaur, P Soria‐Chacartegui, EC Boone, B Prasad, J Dinh, WY Wang, ...
Clinical Pharmacology & Therapeutics 114 (5), 1033-1042, 2023
42023
The impact of the CYP2D6 “enhancer” single nucleotide polymorphism on CYP2D6 activity
JC Dinh, EC Boone, VS Staggs, RE Pearce, WY Wang, R Gaedigk, ...
Clinical Pharmacology & Therapeutics 111 (3), 646-654, 2022
42022
The respective roles of CYP3A4 and CYP2D6 in the metabolism of pimozide to established and novel metabolites
BD Chapron, JC Dinh, PC Toren, A Gaedigk, JS Leeder
Drug Metabolism and Disposition 48 (11), 1113-1120, 2020
42020
Pediatric clinical endpoint and pharmacodynamic biomarkers: limitations and opportunities
JC Dinh, CM Hosey-Cojocari, BL Jones
Pediatric Drugs 22, 55-71, 2020
32020
Cardiac disease alters myocardial tissue levels of epoxyeicosatrienoic acids and key proteins involved in their biosynthesis and degradation
T Aliwarga, JC Dinh, S Heyward, B Prasad, SA Gharib, RN Lemaitre, ...
International Journal of Molecular Sciences 23 (20), 12433, 2022
22022
PROSPECTIVE VALIDATION OF A POPULATION PHARMACOKINETIC MODEL DERIVED DOSING ALGORITHM OF ATOMOXETINE, A CYP2D6 MODEL SUBSTRATE.
JC Dinh, BT Black, BJ Matzuka, KT Gibson, L Van Haandel, A Gaedigk, ...
CLINICAL PHARMACOLOGY & THERAPEUTICS 103, S29-S30, 2018
22018
Principles of drug metabolism 3: enzymes and tissues
BS Raccor, AM Teitelbaum, JC Dinh, RA Totah
Elsevier, 2014
22014
Physiologically Based Pharmacokinetics Modeling in the Neonatal Population—Current Advances, Challenges, and Opportunities
J Dinh, TN Johnson, M Grimstein, T Lewis
Pharmaceutics 15 (11), 2579, 2023
12023
Aggregate bottom-up PBPK models for drug exposure individualization
JC Dinh, B Prasad, JS Leeder
CLINICAL PHARMACOLOGY & THERAPEUTICS 101 (S 1), S7-S7, 2017
12017
Managing Drug Interactions Involving the Over-the-Counter Opioid Loperamide through Physiologically Based Pharmacokinetic Modeling
Z Zhou, M Li, P Zhao, J Dinh, M Paine
Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023
2023
Selective deuteration of bupropion slows epimerization and reduces metabolism
Y Shi, J Dinh, R Pelletier, B Raccor, N Yusuff, AJ Morgan, S Harbeson, ...
Bioorganic & Medicinal Chemistry Letters 76, 129009, 2022
2022
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