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Towards the introduction of the ‘Immunoscore’in the classification of malignant tumours J Galon, B Mlecnik, G Bindea, HK Angell, A Berger, C Lagorce, A Lugli, ... The Journal of pathology 232 (2), 199-209, 2014 | 1471 | 2014 |
Extracellular vesicle and particle biomarkers define multiple human cancers A Hoshino, HS Kim, L Bojmar, KE Gyan, M Cioffi, J Hernandez, ... Cell 182 (4), 1044-1061. e18, 2020 | 803 | 2020 |
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Sensitive tumour detection and classification using plasma cell-free DNA methylomes SY Shen, R Singhania, G Fehringer, A Chakravarthy, MHA Roehrl, ... Nature 563 (7732), 579-583, 2018 | 700 | 2018 |
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ... Nature 538 (7625), 378-382, 2016 | 553 | 2016 |
Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma MA Gillette, S Satpathy, S Cao, SM Dhanasekaran, SV Vasaikar, K Krug, ... Cell 182 (1), 200-225. e35, 2020 | 449 | 2020 |
Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs H Zhu, D Wang, DJ Kelvin, L Li, Z Zheng, SW Yoon, SS Wong, A Farooqui, ... Science 341 (6142), 183-186, 2013 | 357 | 2013 |
A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein− protein interactions by fluorescence … MHA Roehrl, JY Wang, G Wagner Biochemistry 43 (51), 16056-16066, 2004 | 306 | 2004 |
Scleraxis and NFATc regulate the expression of the pro-α1 (I) collagen gene in tendon fibroblasts V Leéjard, G Brideau, F Blais, R Salingcarnboriboon, G Wagner, ... Journal of Biological Chemistry 282 (24), 17665-17675, 2007 | 276 | 2007 |
Proteogenomic characterization of pancreatic ductal adenocarcinoma L Cao, C Huang, DC Zhou, Y Hu, TM Lih, SR Savage, K Krug, DJ Clark, ... Cell 184 (19), 5031-5052. e26, 2021 | 267 | 2021 |
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Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial TL Stockley, AM Oza, HK Berman, NB Leighl, JJ Knox, FA Shepherd, ... Genome medicine 8, 1-12, 2016 | 243 | 2016 |
Selective inhibition of calcineurin-NFAT signaling by blocking protein–protein interaction with small organic molecules MHA Roehrl, S Kang, J Aramburu, G Wagner, A Rao, PG Hogan Proceedings of the National Academy of Sciences 101 (20), 7554-7559, 2004 | 194 | 2004 |
Integration of genomic and transcriptional features in pancreatic cancer reveals increased cell cycle progression in metastases AA Connor, RE Denroche, GH Jang, M Lemire, A Zhang, ... Cancer Cell 35 (2), 267-282. e7, 2019 | 171 | 2019 |
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A dually active anthrax vaccine that confers protection against both bacilli and toxins GE Rhie, MH Roehrl, M Mourez, RJ Collier, JJ Mekalanos, JY Wang Proceedings of the National Academy of Sciences 100 (19), 10925-10930, 2003 | 158 | 2003 |
Single-cell mutation analysis of tumors from stained histologic slides. I Becker, KF Becker, MH Röhrl, G Minkus, K Schütze, H Höfler Laboratory investigation; a journal of technical methods and pathology 75 (6 …, 1996 | 139 | 1996 |
The dawn of the liquid biopsy in the fight against cancer IG Domínguez-Vigil, AK Moreno-Martínez, JY Wang, MHA Roehrl, ... Oncotarget 9 (2), 2912, 2018 | 135 | 2018 |