| PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer C Pantelidou, O Sonzogni, M De Oliveria Taveira, AK Mehta, A Kothari, ... Cancer discovery 9 (6), 722-737, 2019 | 521 | 2019 |
| Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages JL Guerriero, A Sotayo, HE Ponichtera, JA Castrillon, AL Pourzia, ... Nature 543 (7645), 428-432, 2017 | 497 | 2017 |
| The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 402 | 2020 |
| Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma K Bi, MX He, Z Bakouny, A Kanodia, S Napolitano, J Wu, G Grimaldi, ... Cancer cell 39 (5), 649-661. e5, 2021 | 352 | 2021 |
| Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma O Zavidij, NJ Haradhvala, TH Mouhieddine, R Sklavenitis-Pistofidis, S Cai, ... Nature cancer 1 (5), 493-506, 2020 | 266 | 2020 |
| Macrophages: the road less traveled, changing anticancer therapy JL Guerriero Trends in molecular medicine 24 (5), 472-489, 2018 | 264 | 2018 |
| Macrophages: their untold story in T cell activation and function JL Guerriero International Review of Cell and Molecular Biology 342, 73-93, 2019 | 186 | 2019 |
| Genomic evolution and chemoresistance in germ-cell tumours A Taylor-Weiner, T Zack, E O’Donnell, JL Guerriero, B Bernard, A Reddy, ... Nature 540 (7631), 114-118, 2016 | 159 | 2016 |
| BH3 profiling identifies heterogeneous dependency on Bcl-2 family members in multiple myeloma and predicts sensitivity to BH3 mimetics C Touzeau, J Ryan, J Guerriero, P Moreau, TN Chonghaile, S Le Gouill, ... Leukemia 30 (3), 761-764, 2016 | 156 | 2016 |
| Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer AK Mehta, EM Cheney, CA Hartl, C Pantelidou, M Oliwa, JA Castrillon, ... Nature cancer 2 (1), 66-82, 2021 | 154 | 2021 |
| Synergistic immunostimulatory effects and therapeutic benefit of combined histone deacetylase and bromodomain inhibition in non–small cell lung cancer DO Adeegbe, Y Liu, PH Lizotte, Y Kamihara, AR Aref, C Almonte, R Dries, ... Cancer discovery 7 (8), 852-867, 2017 | 138 | 2017 |
| Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes A Marusyk, DP Tabassum, M Janiszewska, AE Place, A Trinh, AI Rozhok, ... Cancer research 76 (22), 6495-6506, 2016 | 131 | 2016 |
| Design, synthesis, and biological evaluation of new-generation taxoids I Ojima, J Chen, L Sun, CP Borella, T Wang, ML Miller, S Lin, X Geng, ... Journal of medicinal chemistry 51 (11), 3203-3221, 2008 | 126 | 2008 |
| The prognostic role of macrophage polarization in the colorectal cancer microenvironment JP Väyrynen, K Haruki, MC Lau, SA Väyrynen, R Zhong, A Dias Costa, ... Cancer immunology research 9 (1), 8-19, 2021 | 121 | 2021 |
| Macrophage biology and mechanisms of immune suppression in breast cancer AK Mehta, S Kadel, MG Townsend, M Oliwa, JL Guerriero Frontiers in immunology 12, 643771, 2021 | 114 | 2021 |
| The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy Z Dou, M Chattopadhyay, JA Pan, JL Guerriero, YP Jiang, LM Ballou, ... Journal of Cell Biology 191 (4), 827-843, 2010 | 104 | 2010 |
| Immune escape during breast tumor progression CR Gil Del Alcazar, M Alečković, K Polyak Cancer immunology research 8 (4), 422-427, 2020 | 101 | 2020 |
| DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity JL Guerriero, D Ditsworth, JM Catanzaro, G Sabino, MB Furie, RR Kew, ... The Journal of Immunology 186 (6), 3517-3526, 2011 | 98 | 2011 |
| The immunology of hormone receptor positive breast cancer J Goldberg, RG Pastorello, T Vallius, J Davis, YX Cui, J Agudo, AG Waks, ... Frontiers in immunology 12, 674192, 2021 | 95 | 2021 |
| Antibody-dependent cellular phagocytosis by macrophages is a novel mechanism of action of elotuzumab AT Kurdi, SV Glavey, NA Bezman, A Jhatakia, JL Guerriero, S Manier, ... Molecular cancer therapeutics 17 (7), 1454-1463, 2018 | 95 | 2018 |
