| A novel bivalent HIV-1 entry inhibitor reveals fundamental differences in CCR5-μ-opioid receptor interactions between human astroglia and microglia N El-Hage, SM Dever, EM Podhaizer, CK Arnatt, Y Zhang, KF Hauser Aids 27 (14), 2181-2190, 2013 | 45 | 2013 |
| A bivalent ligand targeting the putative mu opioid receptor and chemokine receptor CCR5 heterodimer: binding affinity versus functional activities Y Yuan, CK Arnatt, N El-Hage, SM Dever, JC Jacob, DE Selley, ... Medchemcomm 4 (5), 847-851, 2013 | 42 | 2013 |
| Design and synthesis of a bivalent ligand to explore the putative heterodimerization of the mu opioid receptor and the chemokine receptor CCR5 Y Yuan, CK Arnatt, G Li, KM Haney, D Ding, JC Jacob, DE Selley, ... Organic & biomolecular chemistry 10 (13), 2633-2646, 2012 | 38 | 2012 |
| G Protein‐Coupled Estrogen Receptor (GPER) Agonist Dual Binding Mode Analyses Toward Understanding of Its Activation Mechanism: A Comparative Homology Modeling Approach CK Arnatt, Y Zhang Molecular informatics 32 (7), 647-658, 2013 | 36 | 2013 |
| Exploration of bivalent ligands targeting putative mu opioid receptor and chemokine receptor CCR5 dimerization CK Arnatt, BA Falls, Y Yuan, TJ Raborg, RR Masvekar, N El-Hage, ... Bioorganic & medicinal chemistry 24 (22), 5969-5987, 2016 | 32 | 2016 |
| G protein-coupled estrogen receptor, GPER1, offers a novel target for the treatment of digestive diseases C DeLeon, DQH Wang, CK Arnatt Frontiers in Endocrinology 11, 578536, 2020 | 24 | 2020 |
| Asymmetric dibenzothiophene sulfones as fluorescent nuclear stains JT Petroff, KN Skubic, CK Arnatt, RD McCulla The Journal of Organic Chemistry 83 (22), 14063-14068, 2018 | 24 | 2018 |
| Binding mode characterization of 6α-and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis … SA Zaidi, CK Arnatt, H He, DE Selley, PD Mosier, GE Kellogg, Y Zhang Bioorganic & medicinal chemistry 21 (21), 6405-6413, 2013 | 24 | 2013 |
| Design, syntheses, and characterization of piperazine based chemokine receptor CCR5 antagonists as anti prostate cancer agents CK Arnatt, JL Adams, Z Zhang, KM Haney, G Li, Y Zhang Bioorganic & Medicinal Chemistry Letters 24 (10), 2319-2323, 2014 | 23 | 2014 |
| The potential role of anibamine, a natural product CCR5 antagonist, and its analogues as leads toward development of anti-ovarian cancer agents Y Zhang, CK Arnatt, F Zhang, J Wang, KM Haney, X Fang Bioorganic & medicinal chemistry letters 22 (15), 5093-5097, 2012 | 23 | 2012 |
| A series of indole-thiazole derivatives act as GPER agonists and inhibit breast cancer cell growth A O’Dea, C Sondergard, P Sweeney, CK Arnatt ACS medicinal chemistry letters 9 (9), 901-906, 2018 | 22 | 2018 |
| Design, syntheses, and characterization of pharmacophore based chemokine receptor CCR5 antagonists as anti prostate cancer agents CK Arnatt, SA Zaidi, Z Zhang, G Li, AC Richardson, JL Ware, Y Zhang European journal of medicinal chemistry 69, 647-658, 2013 | 21 | 2013 |
| GPR183-oxysterol axis in spinal cord contributes to neuropathic pain K Braden, LA Giancotti, Z Chen, C DeLeon, N Latzo, T Boehm, ... Journal of Pharmacology and Experimental Therapeutics 375 (2), 367-375, 2020 | 20 | 2020 |
| A novel GPER antagonist protects against the formation of estrogen-induced cholesterol gallstones in female mice C DeLeon, HH Wang, J Gunn, MK Wilhelm, A Cole, S Arnett, DQH Wang, ... Journal of Lipid Research 61 (5), 767-777, 2020 | 19 | 2020 |
| Structure activity relationship studies of natural product chemokine receptor CCR5 antagonist anibamine toward the development of novel anti prostate cancer agents F Zhang, CK Arnatt, KM Haney, HC Fang, JE Bajacan, AC Richardson, ... European journal of medicinal chemistry 55, 395-408, 2012 | 19 | 2012 |
| Bivalent ligands targeting chemokine receptor dimerization: molecular design and functional studies C Kent Arnatt, Y Zhang Current topics in medicinal chemistry 14 (13), 1606-1618, 2014 | 18 | 2014 |
| Proteolytic targeting chimeras with specificity for plasma membrane and intracellular estrogen receptors AS Lu, M Rouhimoghadam, CK Arnatt, EJ Filardo, AK Salem Molecular pharmaceutics 18 (3), 1455-1469, 2021 | 17 | 2021 |
| Activation of estrogen receptor G protein–coupled receptor 30 enhances cholesterol cholelithogenesis in female mice HH Wang, O de Bari, CK Arnatt, M Liu, P Portincasa, DQH Wang Hepatology 72 (6), 2077-2089, 2020 | 17 | 2020 |
| The natural product CCR5 antagonist anibamine and its analogs as anti-prostate cancer agents KM Haney, F Zhang, CK Arnatt, Y Yuan, G Li, JL Ware, DA Gewirtz, ... Bioorganic & medicinal chemistry letters 21 (18), 5159-5163, 2011 | 16 | 2011 |
| Sphingosine-1-phosphate receptor 1 activation in the central nervous system drives cisplatin-induced cognitive impairment S Squillace, ML Niehoff, TM Doyle, M Green, E Esposito, S Cuzzocrea, ... The Journal of Clinical Investigation 132 (17), 2022 | 13 | 2022 |
