| A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing A Edraki, A Mir, R Ibraheim, I Gainetdinov, Y Yoon, CQ Song, Y Cao, ... Molecular cell 73 (4), 714-726. e4, 2019 | 232 | 2019 |
| NmeCas9 is an intrinsically high-fidelity genome-editing platform N Amrani, XD Gao, P Liu, A Edraki, A Mir, R Ibraheim, A Gupta, KE Sasaki, ... Genome Biology 19, 1-25, 2018 | 130 | 2018 |
| All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo R Ibraheim, CQ Song, N Mir, Aamir, Amrani, EJ Xue, Sontheimer, Wen Genome Biology 19 (137), 2018 | 108 | 2018 |
| Potent Cas9 inhibition in bacterial and human cells by AcrIIC4 and AcrIIC5 anti-CRISPR proteins J Lee, A Mir, A Edraki, B Garcia, N Amrani, HE Lou, I Gainetdinov, ... MBio 9 (6), 10.1128/mbio. 02321-18, 2018 | 92 | 2018 |
| Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins J Lee, H Mou, R Ibraheim, SQ Liang, P Liu, W Xue, EJ Sontheimer Rna 25 (11), 1421-1431, 2019 | 89 | 2019 |
| Structures of Neisseria meningitidis Cas9 complexes in catalytically poised and anti-CRISPR-inhibited states W Sun, J Yang, Z Cheng, N Amrani, C Liu, K Wang, R Ibraheim, A Edraki, ... Molecular cell 76 (6), 938-952. e5, 2019 | 83 | 2019 |
| Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo R Ibraheim, PWL Tai, A Mir, N Javeed, J Wang, TC Rodríguez, ... Nature communications 12 (1), 6267, 2021 | 65 | 2021 |
| A scalable and accurate method for quantifying vector genomes of recombinant adeno-associated viruses in crude lysate J Ai, R Ibraheim, PWL Tai, G Gao Human gene therapy methods 28 (3), 139-147, 2017 | 47 | 2017 |
| CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease E Tsagkaraki, SM Nicoloro, T DeSouza, J Solivan-Rivera, A Desai, ... Nature Communications 12 (1), 6931, 2021 | 44 | 2021 |
| Syntheses, characterization, density functional theory calculations, and activity of tridentate SNS zinc pincer complexes based on bis-imidazole or bis-triazole precursors JR Miecznikowski, W Lo, MA Lynn, S Jain, LC Keilich, NF Kloczko, ... Inorganica Chimica Acta 387, 25-36, 2012 | 41 | 2012 |
| Efficient homology-directed repair with circular single-stranded DNA donors S Iyer, A Mir, J Vega-Badillo, BP Roscoe, R Ibraheim, LJ Zhu, J Lee, P Liu, ... The CRISPR Journal 5 (5), 685-701, 2022 | 18 | 2022 |
| Efficient homology-directed repair with circular ssDNA donors S Iyer, A Mir, J Vega-Badillo, BP Roscoe, R Ibraheim, LJ Zhu, J Lee, P Liu, ... bioRxiv, 864199, 2019 | 11 | 2019 |
| Targeted CRISPR Delivery Platforms EJ Sontheimer, R Ibraheim, W Xue, A Mir, A Edraki, I Gainetdinov US Patent App. 16/186,352, 2022 | 1 | 2022 |
| Correction of the Human Wilson’s Disease Mutation in an Engineered Disease Mouse Model Using RNA Gene Writers R Ibraheim, M Bedekar, L Apponi, E English, S Sun, M Caldwell, CZ Cai, ... 27th Annual Meeting of the American Society of Gene & Cell Therapy 32 (4), 306, 2024 | | 2024 |
| LNP-AAV Hybrid Delivery of a DNA Gene Writer System Corrects Severe Ornithine Transcarbamylase Deficiency in Neonatal Mice and Improves AAV Potency in Adult Mouse and NHP Livers 26th Annual Meeting of the American Society of Gene & Cell Therapy 31 (4), 619, 2023 | | 2023 |
| Direct ITR-To-ITR Nanopore Sequencing of Plasmid and Vector Preparations and Their Implications for In Vivo Gene-Editing Vector Performance S Namkung, R Ibraheim, NT Tran, E Sontheimer, G Gao, P Tai MOLECULAR THERAPY 30 (4), 22-23, 2022 | | 2022 |
| Genome Engineering Goes Viral: Repurposing of Adeno-associated Viral Vectors for CRISPR-mediated in Vivo Genome Engineering RR Ibraheim | | 2020 |
| Tissue-specific Genome Editing in vivo by MicroRNA-repressible Anti-CRISPR Proteins [preprint] J Lee, H Mou, R Ibraheim, SQ Liang, W Xue, EJ Sontheimer | | 2019 |
| Tissue-specific Genome Editing in vivo by MicroRNA-repressible Anti-CRISPR Proteins J Lee, H Mou, R Ibraheim, SQ Liang, W Xue, E Sontheimer bioRxiv, 631689, 2019 | | 2019 |
| Advances in Genome Editing Using Adeno-Associated Virus Delivery of a Compact, Hyper-Accurate Cas9 with a Dinucleotide PAM RR Ibraheim, A Edraki, A Mir, I Gainetdinov, Y Yoon, CQ Song, W Xue, ... MOLECULAR THERAPY 27 (4), 447-447, 2019 | | 2019 |
Erik SontheimerRNA Therapeutics Institute, UMass Medical SchoolVerified email at umassmed.edu
