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Wenhui He
Wenhui He
Senior Staff Scientist
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
H Yan, G Zhong, G Xu, W He, Z Jing, Z Gao, Y Huang, Y Qi, B Peng, ...
elife 1, e00049, 2012
22932012
Viral entry of hepatitis B and D viruses and bile salts transportation share common molecular determinants on sodium taurocholate cotransporting polypeptide
H Yan, B Peng, Y Liu, G Xu, W He, B Ren, Z Jing, J Sui, W Li
Journal of virology 88 (6), 3273-3284, 2014
2892014
Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense
X Wang, Y Li, S Liu, X Yu, L Li, C Shi, W He, J Li, L Xu, Z Hu, L Yu, Z Yang, ...
Proceedings of the National Academy of Sciences 111 (43), 15438-15443, 2014
2222014
Molecular determinants of hepatitis B and D virus entry restriction in mouse sodium taurocholate cotransporting polypeptide
H Yan, B Peng, W He, G Zhong, Y Qi, B Ren, Z Gao, Z Jing, M Song, G Xu, ...
Journal of virology 87 (14), 7977-7991, 2013
2162013
DNA polymerase κ is a key cellular factor for the formation of covalently closed circular DNA of hepatitis B virus
Y Qi, Z Gao, G Xu, B Peng, C Liu, H Yan, Q Yao, G Sun, Y Liu, D Tang, ...
PLoS pathogens 12 (10), e1005893, 2016
2032016
The SARS-CoV-2 receptor-binding domain elicits a potent neutralizing response without antibody-dependent enhancement
BD Quinlan, H Mou, L Zhang, Y Guo, W He, A Ojha, MS Parcells, G Luo, ...
Biorxiv, 2020.04. 10.036418, 2020
1482020
Hepatitis D virus infection of mice expressing human sodium taurocholate co-transporting polypeptide
W He, B Ren, F Mao, Z Jing, Y Li, Y Liu, B Peng, H Yan, Y Qi, Y Sun, ...
PLoS pathogens 11 (4), e1004840, 2015
1282015
A potent human neutralizing antibody Fc-dependently reduces established HBV infections
D Li, W He, X Liu, S Zheng, Y Qi, H Li, F Mao, J Liu, Y Sun, L Pan, K Du, ...
Elife 6, e26738, 2017
1082017
Sodium taurocholate cotransporting polypeptide mediates woolly monkey hepatitis B virus infection of Tupaia hepatocytes
G Zhong, H Yan, H Wang, W He, Z Jing, Y Qi, L Fu, Z Gao, Y Huang, G Xu, ...
Journal of virology 87 (12), 7176-7184, 2013
832013
A reversible RNA on-switch that controls gene expression of AAV-delivered therapeutics in vivo
G Zhong, H Wang, W He, Y Li, H Mou, ZJ Tickner, MH Tran, T Ou, Y Yin, ...
Nature biotechnology 38 (2), 169-175, 2020
732020
Modification of Three Amino Acids in Sodium Taurocholate Cotransporting Polypeptide Renders Mice Susceptible to Infection with Hepatitis D Virus In Vivo
W He, Z Cao, F Mao, B Ren, Y Li, D Li, H Li, B Peng, H Yan, Y Qi, Y Sun, ...
Journal of virology 90 (19), 8866-8874, 2016
512016
Silencing retinoid X receptor alpha expression enhances early-stage hepatitis B virus infection in cell cultures
M Song, Y Sun, J Tian, W He, G Xu, Z Jing, W Li
Journal of virology 92 (8), 10.1128/jvi. 01771-17, 2018
412018
Increased sulfation of bile acids in mice and human subjects with sodium taurocholate cotransporting polypeptide deficiency
F Mao, T Liu, X Hou, H Zhao, W He, C Li, Z Jing, J Sui, F Wang, X Liu, ...
Journal of Biological Chemistry 294 (31), 11853-11862, 2019
322019
microRNA expression in hepatitis B virus infected primary treeshrew hepatocytes and the independence of intracellular miR-122 level for de novo HBV infection in culture
G Xu, Z Gao, W He, Y Ma, X Feng, T Cai, F Lu, L Liu, W Li
Virology 448, 247-254, 2014
252014
Effect of mRNA-LNP components of two globally-marketed COVID-19 vaccines on efficacy and stability
L Zhang, KR More, A Ojha, CB Jackson, BD Quinlan, H Li, W He, ...
npj Vaccines 8 (1), 156, 2023
232023
A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium MA2020
MH Tran, H Park, CL Nobles, P Karunadharma, L Pan, G Zhong, H Wang, ...
Molecular Therapy-Nucleic Acids 24, 40-53, 2021
232021
An engineered receptor-binding domain improves the immunogenicity of multivalent SARS-CoV-2 vaccines
Y Guo, W He, H Mou, L Zhang, J Chang, S Peng, A Ojha, R Tavora, ...
Mbio 12 (3), 10.1128/mbio. 00930-21, 2021
192021
Potent and specific inhibition of NTCP-mediated HBV/HDV infection and substrate transporting by a novel, oral-available cyclosporine A analogue
Y Liu, H Ruan, Y Li, G Sun, X Liu, W He, F Mao, M He, L Yan, G Zhong, ...
Journal of medicinal chemistry 64 (1), 543-565, 2020
172020
Reprogramming of the heavy-chain CDR3 regions of a human antibody repertoire
T Ou, W He, BD Quinlan, Y Guo, MH Tran, P Karunadharma, H Park, ...
Molecular Therapy 30 (1), 184-197, 2022
102022
NTCP Deficiency causes gallbladder abnormalities in mice and human beings
F Mao, MX Wang, X Hou, Z Zhou, YY Yan, LJ Fang, Z Tan, WY Fang, T Liu, ...
Cellular and Molecular Gastroenterology and Hepatology 11 (3), 831-839, 2021
102021
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