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Laura Sipe
Laura Sipe
Verified email at umw.edu
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Year
Microbiome, bile acids, and obesity: How microbially modified metabolites shape anti‐tumor immunity
LM Sipe, M Chaib, AK Pingili, JF Pierre, L Makowski
Immunological Reviews 295 (1), 220-239, 2020
502020
Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
AK Pingili, M Chaib, LM Sipe, EJ Miller, B Teng, R Sharma, JR Yarbro, ...
Cell reports 35 (12), 2021
492021
Dopamine signaling in the suprachiasmatic nucleus enables weight gain associated with hedonic feeding
RM Grippo, Q Tang, Q Zhang, SR Chadwick, Y Gao, EB Altherr, L Sipe, ...
Current Biology 30 (2), 196-208. e8, 2020
482020
Sphingosine-1-phosphate Phosphatase 1 Regulates Keratinocyte Differentiation and Epidermal Homeostasis*♦
ML Allende, LM Sipe, G Tuymetova, KL Wilson-Henjum, W Chen, ...
Journal of Biological Chemistry 288 (25), 18381-18391, 2013
472013
Differential sympathetic outflow to adipose depots is required for visceral fat loss in response to calorie restriction
LM Sipe, C Yang, J Ephrem, E Garren, J Hirsh, CD Deppmann
Nutrition & Diabetes 7 (4), e260-e260, 2017
292017
The p75 neurotrophin receptor in AgRP neurons is necessary for homeostatic feeding and food anticipation
B Podyma, DA Johnson, L Sipe, TP Remcho, K Battin, Y Liu, SO Yoon, ...
Elife 9, e52623, 2020
172020
The role of obesity and bariatric surgery-induced weight loss in breast cancer
MS Bohm, LM Sipe, ME Pye, MJ Davis, JF Pierre, L Makowski
Cancer and Metastasis Reviews 41 (3), 673-695, 2022
132022
Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery
LM Sipe, M Chaib, EB Korba, H Jo, MC Lovely, BR Counts, U Tanveer, ...
Elife 11, e79143, 2022
122022
PKC agonism restricts innate immune suppression, promotes antigen cross-presentation and synergizes with agonistic CD40 antibody therapy to activate CD8+ T cells in breast cancer
M Chaib, LM Sipe, JR Yarbro, MS Bohm, BR Counts, U Tanveer, ...
Cancer letters 531, 98-108, 2022
82022
Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer
M Chaib, JR Holt, EL Fisher, LM Sipe, MS Bohm, SC Joseph, ...
Science Advances 9 (51), eadd3231, 2023
32023
Myeloid PKCd activation inhibits innate immune suppression and promotes antigen cross-presentation in triple negative breast cancer
M Chaib, J Holt, L Sipe, A Pingili, TJ Hollingsworth, D Daria, N Hayes, ...
Cancer Research 81 (13_Supplement), 118-118, 2021
12021
Novel pre-clinical model to identify genetic modifiers of triple negative breast cancer
LM Sipe, EB Korba, L Lu, RW Williams, DG Ashbrook, L Makowski
Cancer Research 81 (13_Supplement), 2919-2919, 2021
12021
SAT-602 Hypothalamic P75 Neurotrophin Receptor Regulates Homeostatic Feeding and Food Anticipation
B Podyma, D Johnson, L Sipe, K Battin, P Remcho, CD Deppmann, ...
Journal of the Endocrine Society 4 (Supplement_1), SAT-602, 2020
12020
FXR agonism with bile acid mimetic reduces pre-clinical triple-negative breast cancer burden
SC Joseph, S Eugin Simon, MS Bohm, M Kim, ME Pye, BW Simmons, ...
Cancers 16 (7), 1368, 2024
2024
Determining susceptibility loci in triple negative breast cancer using a novel pre-clinical model
SE Simon, BW Simmons, M Kim, SC Joseph, E Korba, SJ Marathe, ...
bioRxiv, 2024.02. 08.579359, 2024
2024
1325 Bariatric surgery-induced modulation of gut microbiota improves response to αPD-1 immunotherapy in preclinical model of breast cancer after bariatric surgery
MS Bohm, LM Sipe, SC Joseph, BW Simmons, ME Pye, AM Sidebottom, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
PKC AGONISM RESTRICTS INNATE IMMUNE SUPPRESSION, PROMOTES ANTIGEN CROSS-PRESENTATION AND SYNERGIZES WITH AGONISTIC CD40 THERAPY IN BREAST CANCER
M Chaib, L Makowski, J Yarbro, L Sipe, D Daria
JOURNAL FOR IMMUNOTHERAPY OF CANCER 9, A710-A710, 2021
2021
682 PKC agonism restricts innate immune suppression, promotes antigen cross-presentation and synergizes with agonistic CD40 therapy in breast cancer
M Chaib, L Makowski, J Yarbro, L Sipe, D Daria
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021
2021
Abstract PS17-29: Surgically induced weight loss corrects obesity associated tumor progression and improves responsiveness to immunotherapy
L Sipe, M Chaib, EB Korba, MC Lovely, JC Clements, NA John, AK Pingili, ...
Cancer Research 81 (4_Supplement), PS17-29-PS17-29, 2021
2021
Abstract PS17-46: Pkc agonism restricts immune suppression and promotes antigen cross-presentation in triple negative breast cancer
M Chaib, J Holt, L Sipe, A Pingili, D Daria, L Makowski
Cancer Research 81 (4_Supplement), PS17-46-PS17-46, 2021
2021
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