Microbiome, bile acids, and obesity: How microbially modified metabolites shape anti‐tumor immunity LM Sipe, M Chaib, AK Pingili, JF Pierre, L Makowski Immunological Reviews 295 (1), 220-239, 2020 | 50 | 2020 |
Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer AK Pingili, M Chaib, LM Sipe, EJ Miller, B Teng, R Sharma, JR Yarbro, ... Cell reports 35 (12), 2021 | 49 | 2021 |
Dopamine signaling in the suprachiasmatic nucleus enables weight gain associated with hedonic feeding RM Grippo, Q Tang, Q Zhang, SR Chadwick, Y Gao, EB Altherr, L Sipe, ... Current Biology 30 (2), 196-208. e8, 2020 | 48 | 2020 |
Sphingosine-1-phosphate Phosphatase 1 Regulates Keratinocyte Differentiation and Epidermal Homeostasis*♦ ML Allende, LM Sipe, G Tuymetova, KL Wilson-Henjum, W Chen, ... Journal of Biological Chemistry 288 (25), 18381-18391, 2013 | 47 | 2013 |
Differential sympathetic outflow to adipose depots is required for visceral fat loss in response to calorie restriction LM Sipe, C Yang, J Ephrem, E Garren, J Hirsh, CD Deppmann Nutrition & Diabetes 7 (4), e260-e260, 2017 | 29 | 2017 |
The p75 neurotrophin receptor in AgRP neurons is necessary for homeostatic feeding and food anticipation B Podyma, DA Johnson, L Sipe, TP Remcho, K Battin, Y Liu, SO Yoon, ... Elife 9, e52623, 2020 | 17 | 2020 |
The role of obesity and bariatric surgery-induced weight loss in breast cancer MS Bohm, LM Sipe, ME Pye, MJ Davis, JF Pierre, L Makowski Cancer and Metastasis Reviews 41 (3), 673-695, 2022 | 13 | 2022 |
Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery LM Sipe, M Chaib, EB Korba, H Jo, MC Lovely, BR Counts, U Tanveer, ... Elife 11, e79143, 2022 | 12 | 2022 |
PKC agonism restricts innate immune suppression, promotes antigen cross-presentation and synergizes with agonistic CD40 antibody therapy to activate CD8+ T cells in breast cancer M Chaib, LM Sipe, JR Yarbro, MS Bohm, BR Counts, U Tanveer, ... Cancer letters 531, 98-108, 2022 | 8 | 2022 |
Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer M Chaib, JR Holt, EL Fisher, LM Sipe, MS Bohm, SC Joseph, ... Science Advances 9 (51), eadd3231, 2023 | 3 | 2023 |
Myeloid PKCd activation inhibits innate immune suppression and promotes antigen cross-presentation in triple negative breast cancer M Chaib, J Holt, L Sipe, A Pingili, TJ Hollingsworth, D Daria, N Hayes, ... Cancer Research 81 (13_Supplement), 118-118, 2021 | 1 | 2021 |
Novel pre-clinical model to identify genetic modifiers of triple negative breast cancer LM Sipe, EB Korba, L Lu, RW Williams, DG Ashbrook, L Makowski Cancer Research 81 (13_Supplement), 2919-2919, 2021 | 1 | 2021 |
SAT-602 Hypothalamic P75 Neurotrophin Receptor Regulates Homeostatic Feeding and Food Anticipation B Podyma, D Johnson, L Sipe, K Battin, P Remcho, CD Deppmann, ... Journal of the Endocrine Society 4 (Supplement_1), SAT-602, 2020 | 1 | 2020 |
FXR agonism with bile acid mimetic reduces pre-clinical triple-negative breast cancer burden SC Joseph, S Eugin Simon, MS Bohm, M Kim, ME Pye, BW Simmons, ... Cancers 16 (7), 1368, 2024 | | 2024 |
Determining susceptibility loci in triple negative breast cancer using a novel pre-clinical model SE Simon, BW Simmons, M Kim, SC Joseph, E Korba, SJ Marathe, ... bioRxiv, 2024.02. 08.579359, 2024 | | 2024 |
1325 Bariatric surgery-induced modulation of gut microbiota improves response to αPD-1 immunotherapy in preclinical model of breast cancer after bariatric surgery MS Bohm, LM Sipe, SC Joseph, BW Simmons, ME Pye, AM Sidebottom, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
PKC AGONISM RESTRICTS INNATE IMMUNE SUPPRESSION, PROMOTES ANTIGEN CROSS-PRESENTATION AND SYNERGIZES WITH AGONISTIC CD40 THERAPY IN BREAST CANCER M Chaib, L Makowski, J Yarbro, L Sipe, D Daria JOURNAL FOR IMMUNOTHERAPY OF CANCER 9, A710-A710, 2021 | | 2021 |
682 PKC agonism restricts innate immune suppression, promotes antigen cross-presentation and synergizes with agonistic CD40 therapy in breast cancer M Chaib, L Makowski, J Yarbro, L Sipe, D Daria Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | | 2021 |
Abstract PS17-29: Surgically induced weight loss corrects obesity associated tumor progression and improves responsiveness to immunotherapy L Sipe, M Chaib, EB Korba, MC Lovely, JC Clements, NA John, AK Pingili, ... Cancer Research 81 (4_Supplement), PS17-29-PS17-29, 2021 | | 2021 |
Abstract PS17-46: Pkc agonism restricts immune suppression and promotes antigen cross-presentation in triple negative breast cancer M Chaib, J Holt, L Sipe, A Pingili, D Daria, L Makowski Cancer Research 81 (4_Supplement), PS17-46-PS17-46, 2021 | | 2021 |