CTCF binding sites promote transcription initiation and prevent DNA methylation on the maternal allele at the imprinted H19/Igf2 locus N Engel, JL Thorvaldsen, MS Bartolomei Human molecular genetics 15 (19), 2945-2954, 2006 | 186 | 2006 |
The Kcnq1ot1 Long Non-Coding RNA Affects Chromatin Conformation and Expression of Kcnq1, but Does Not Regulate Its Imprinting in the Developing Heart L Korostowski, N Sedlak, N Engel Public Library of Science 8 (9), e1002956, 2012 | 169 | 2012 |
Antagonism between DNA hypermethylation and enhancer-blocking activity at the H19 DMD is uncovered by CpG mutations N Engel, AG West, G Felsenfeld, MS Bartolomei Nature genetics 36 (8), 883-888, 2004 | 148 | 2004 |
Conserved DNA methylation in Gadd45a-/- mice N Engel, JS Tront, T Erinle, N Nguyen, KE Latham, C Sapienza, ... Epigenetics 4 (2), 98-99, 2009 | 102 | 2009 |
Histamine as an autocrine growth factor: an unusual role for a widespread mediator ES Rivera, GP Cricco, NI Engel, CP Fitzsimons, GA Martı́n, RM Bergoc Seminars in cancer biology 10 (1), 15-23, 2000 | 100 | 2000 |
Histamine as an autocrine growth factor in experimental mammary carcinomas GP Cricco, CA Davio, G Martin, N Engel, CP Fitzsimons, RM Bergoc, ... Agents and actions 43, 17-20, 1994 | 77 | 1994 |
The epigenetic lorax: gene–environment interactions in human health KE Latham, C Sapienza, N Engel Epigenomics 4 (4), 383-402, 2012 | 76 | 2012 |
Three-dimensional conformation at the H19 / Igf2 locus supports a model of enhancer tracking N Engel, AK Raval, JL Thorvaldsen, SM Bartolomei Human molecular genetics 17 (19), 3021-3029, 2008 | 70 | 2008 |
A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer CR Good, J Madzo, B Patel, S Maegawa, N Engel, J Jelinek, JPJ Issa Nucleic Acids Research 45 (14), 8269-8281, 2017 | 65 | 2017 |
Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells RJ Werner, BM Schultz, JM Huhn, J Jelinek, J Madzo, N Engel Biology of sex differences 8 (1), 1-18, 2017 | 54 | 2017 |
Enhancer-driven chromatin interactions during development promote escape from silencing by a long non-coding RNA L Korostowski, A Raval, G Breuer, N Engel Epigenetics & chromatin 4, 1-11, 2011 | 41 | 2011 |
Enhancers compete with a long non-coding RNA for regulation of the Kcnq1 domain BM Schultz, GA Gallicio, M Cesaroni, LN Lupey, N Engel Nucleic Acids Research 43 (2), 745-759, 2015 | 40 | 2015 |
Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation L Barrio-Real, LG Benedetti, N Engel, Y Tu, S Cho, S Sukumar, ... Breast Cancer Research 16 (5), 1-13, 2014 | 39 | 2014 |
Expression of c-myc and c-fos protooncogenes in the anterior pituitary gland of the rat. Effect of estrogen I Szijan, DL Parma, NI Engel Hormone and metabolic research 24 (04), 154-157, 1992 | 37 | 1992 |
Sexual dimorphism in the age of genomics: how, when, where DF Deegan, N Engel Frontiers in cell and developmental biology 7, 186, 2019 | 36 | 2019 |
Experimental evidence for structure-activity features in common between mammalian histidine decarboxylase and ornithine decarboxylase N Engel, MT Olmo, CS Coleman, MA Medina, AE Pegg, ... Biochemical Journal 320 (2), 365-368, 1996 | 35 | 1996 |
The developmental origins of sex-biased expression in cardiac development DF Deegan, R Karbalaei, J Madzo, RJ Kulathinal, N Engel Biology of sex Differences 10, 1-20, 2019 | 34 | 2019 |
Novel cis-regulatory function in ICR-mediated imprinted repression of H19 FY Ideraabdullah, LK Abramowitz, JL Thorvaldsen, C Krapp, SC Wen, ... Developmental biology 355 (2), 349-357, 2011 | 33 | 2011 |
Regulation of phospholipase C activation by the number of H2 receptors during Ca2+-induced differentiation of mouse keratinocytes C Fitzsimons, N Engel, L Policastro, H Durán, B Molinari, E Rivera Biochemical pharmacology 63 (10), 1785-1796, 2002 | 31 | 2002 |
Mechanisms of insulator function in gene regulation and genomic imprinting N Engel, MS Bartolomei International review of cytology 232, 89-128, 2003 | 29 | 2003 |