A rapid in vivo test for chromosomal damage JA Heddle Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 18 (2 …, 1973 | 1182 | 1973 |
The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes PI Countryman, JA Heddle Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 41 (2 …, 1976 | 1099 | 1976 |
The induction of micronuclei as a measure of genotoxicity: A report of the US Environmental Protection Agency Gene-Tox Program JA Heddle, M Hite, B Kirkhart, K Mavournin, JT MacGregor, GW Newell, ... Mutation Research/Reviews in Genetic Toxicology 123 (1), 61-118, 1983 | 1049 | 1983 |
Micronuclei as an index of cytogenetic damage: past, present, and future JA Heddle, MC Cimino, M Hayashi, F Romagna, MD Shelby, JD Tucker, ... Environmental and molecular mutagenesis 18 (4), 277-291, 1991 | 775 | 1991 |
The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the US Environmental Protection Agency Gene-Tox Program KH Mavournin, DH Blakey, MC Cimino, MF Salamone, JA Heddle Mutation Research/Reviews in Genetic Toxicology 239 (1), 29-80, 1990 | 609 | 1990 |
Guidelines for the conduct of micronucleus assays in mammalian bone marrow erythrocytes JT MacGregor, JA Heddle, M Hite, BH Margolin, C Ramel, MF Salamone, ... Mutation Research/Genetic Toxicology 189 (2), 103-112, 1987 | 473 | 1987 |
Mammalian in vivo and in vitro cytogenetic assays: A report of the US EPA's Gene-Tox Program RJ Preston, W Au, MA Bender, JG Brewen, AV Carrano, JA Heddle, ... Mutation Research/Reviews in Genetic Toxicology 87 (2), 143-188, 1981 | 387 | 1981 |
THE MUTAGENIC ACTIVITY OF 61 AGENTS AS DETERMINED BY THE MICRONUCLEUS, SALMONELLA, AND SPERM ABNORMALITY ASSAYS WR Bruce, JA Heddle Canadian Journal of Genetics and Cytology 21 (3), 319-333, 1979 | 361 | 1979 |
The DNA content of micronuclei induced in mouse bone marrow by γ-irradiation: evidence that micronuclei arise from acentric chromosomal fragments JA Heddle, AV Carrano Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 44 (1 …, 1977 | 333 | 1977 |
DNA polymerase ε and δ proofreading suppress discrete mutator and cancer phenotypes in mice TM Albertson, M Ogawa, JM Bugni, LE Hays, Y Chen, Y Wang, ... Proceedings of the National Academy of Sciences 106 (40), 17101-17104, 2009 | 255 | 2009 |
The fate of chromosome aberrations AV Carrano, JA Heddle Journal of theoretical biology 38 (2), 289-304, 1973 | 206 | 1973 |
Towards an improved micronucleus test Studies on 3 model agents, mitomycin C, cyclophosphamide and dimethylbenzanthracene M Salamone, J Heddle, E Stuart, M Katz Mutation Research/Environmental Mutagenesis and Related Subjects 74 (5), 347-356, 1980 | 203 | 1980 |
Recommended protocols based on a survey of current practice in genotoxicity testing laboratories, IV. Chromosome aberration and sister-chromatid exchange in Chinese hamster … SHH Swierenga, JA Heddle, EA Sigal, JPW Gilman, RL Brillinger, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 246 (2 …, 1991 | 180 | 1991 |
Comparison of tests for mutagenicity or carcinogenicity using assays for sperm abnormalities, formation of micronuclei, and mutations in Salmonella JA Heddle, WR Bruce Origins of human cancer 100, 1549-1557, 1977 | 154 | 1977 |
In vivo transgenic mutation assays V Thybaud, S Dean, T Nohmi, J de Boer, GR Douglas, BW Glickman, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 540 (2 …, 2003 | 153 | 2003 |
Comparison of somatic mutation in a transgenic versus host locus. KS Tao, C Urlando, JA Heddle Proceedings of the National Academy of Sciences 90 (22), 10681-10685, 1993 | 152 | 1993 |
Proliferation is necessary for both repair and mutation in transgenic mouse cells JH Bielas, JA Heddle Proceedings of the National Academy of Sciences 97 (21), 11391-11396, 2000 | 128 | 2000 |
In vivo transgenic mutation assays JA Heddle, S Dean, T Nohmi, M Boerrigter, D Casciano, GR Douglas, ... Environmental and molecular mutagenesis 35 (3), 253-259, 2000 | 127 | 2000 |
Sensitivity to five mutagens in Fanconi's anemia as measured by the micronucleus method JA Heddle, CB Lue, EF Saunders, RD Benz Cancer research 38 (9), 2983-2988, 1978 | 127 | 1978 |
The bone marrow micronucleus assay: rationale for a revised protocol MF Salamone, JA Heddle Chemical Mutagens: Principles and Methods for Their Detection Volume 8, 111-149, 1983 | 124 | 1983 |